Fluorescent in situ hybridization (FISH) is a technique that helps visualize the location of a particular gene or DNA sequence in a person’s genome. This information assists a scientist in identifying specific chromosomal alterations that could have caused specific genetic conditions.
The fluorescent in situ hybridization probe market was worth USD 995 million in 2014. It would grow at a CAGR of 6.9% from 2015 to 2022 (forecast period). Rising target diseases are fueling the demand for in-vitro diagnostics (IVD), and consequently FISH probes.
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Other factors favoring the market include healthcare deployments and awareness of FISH probe-based assays. Adoption of FISH in molecular diagnostic studies is also beneficial. The market is categorized on the basis of RNAs – Ribonucleic Acids, technologies, end-users, applications, and regions. RNAs comprise mRNA (messenger RNA), miRNA (micro RNA), and others.
mRNA, with 34% shares, was the leader of the fluorescent in situ hybridization probe market in 2014. Demand for molecular profiling and escalating applications of mRNA in the detection & validation of cytogenetic diseases are its drivers. This segment will also benefit from innovations in molecular pathology. These innovations facilitate accurate disease prognosis & suitable treatment. miRNA is set to grow at a CAGR exceeding 6.9% during the forecast period.
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Technology segments comprise FISH, Flow FISH, CISH, Q FISH, and DISH. FISH was the dominant technology in 2014. It fetched around USD 305 million that year. CISH should grow at a CAGR of 7.4% over the next seven years. Flow FISH is also expected to grow lucratively in the future.
Research, companion diagnostics, and clinical procedures constitute the end-users of the fluorescent in situ hybridization probe market. Clinical procedures accounted for around 41% of the market in 2014. The wide applications of FISH probes in detecting genetic disorders, cancer, and infectious diseases are the main reason for the dominance of FISH probes in clinical procedures.
Application segments include lung cancer, breast cancer, cancer diagnostics, and genetic diseases. Cancer diagnostics and genetic diseases occupied significant spots in 2014. Cancer diagnostics held a share of 41% in terms of incomes the same year.
Regions of the fluorescent in situ hybridization probe market comprise North America, Asia Pacific, Europe, and Rest of the World (RoW). North America led the market in 2014. Asia Pacific would grow owing to untapped nations, improving healthcare infrastructure, economic growth, and higher patient awareness.
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