Worldwide: The new report, entitled GLOBAL PRENATAL AND MATERNAL DIAGNOSTIC MARKET ANALYSIS to 2021 indicates that the launch of noninvasive prenatal screening tests (NIPTs) in 2011 dramatically altered the market dynamic, and this sub-section of the market will see an 18% CAGR to 2021. This is at the expense of more invasive techniques as chorionic villus sampling (CVS) or amniocentesis.
Since the 1960s, technologies for testing fetuses for conditions including trisomies have been continually advancing. The initial nongenetic testing such as ultrasound and serum screening for protein level markers, have developed remarkably throughout the years. Yet, these conventional tests are limited in sensitivity and specificity. Parallel to the development of these conventional technologies, two invasive techniques called amniocentesis and chorionic villus sampling (CVS) were introduced in 1980s to offer near 100% detection rates for trisomies. Yet, the chances of injury to the fetus and the consequence of miscarriages deterred both patients and obstetricians from using these techniques and to this date the techniques are used in high-risk pregnancies for the confirmation of positive results from screening tests.
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When human genome sequencing was successfully accomplished, experts in the healthcare industry expected that DNA sequencing would mainly focus on genetic diseases in adults. Instead, the impact of sequencing technology has been primarily on prenatal, newborn and preimplantation genetic diagnosis (PGD) tests (prior to in vitro fertilization). In a short span of four years, the different types of maternal serum screening tests and fetal ultrasound tests are getting gradually replaced by the new technology of non-invasive prenatal tests (NIPTs). In the past four years, hundreds and thousands of these new tests have been performed in screening cffDNA from maternal blood.
The objective of this report is to provide an overview of the various technologies being employed for detecting genetic diseases in embryos, fetuses and newborns. The various chapters describe common pregnancy disorders, numerical chromosome disorders and structural chromosome disorders, single gene disorders inherited by fetuses, newborns and embryos. The global prenatal and maternal diagnostic test market is assessed with respect to:
• Fetal Ultrasound
• Prenatal MRI Screening
• Maternal Serum Screening Tests
• Noninvasive Prenatal Tests (NIPTs) using cffDNA
• NIPTs by Product
• Prenatal Diagnostic Invasive Tests
• Newborn Screening for Genetic Diseases
• Newborn Screening Market by Technology
• Preimplantation Screening/Diagnosis (PGS/PGD) and carrier screening tests
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SWOT and merger/acquisition analysis is also performed as is a comprehensive documentation of the legislation pertaining to newborn screening by geography and how clinical programs are implemented in developed and developing markets.
Emerging trends in associated markets are also analysed in order to give the reader a comprehensive overview of how prenatal and maternal diagnostic testing is affected by the following industries:
• Molecular Diagnostics Market
• Liquid Biopsy Market
• Personalized Medicine Diagnostics Market
• In vitro Diagnostics (IVD) Market
This is a comprehensive 390 page report strengthened with over 280 figures and tables. Published in September 2016, the GLOBAL PRENATAL & MATERNAL DIAGNOSTIC MARKET TO 2021 has a detailed overview of 114 companies in the market with specifics pertaining to financial and business strategy, current products on the market and pipeline products.
For more information on report visit https://marketreportscenter.com/reports/386361/global-prenatal-maternal-diagnostic-market-to-2021
Key Questions Answered in this Report
• What are the major prenatal pregnancy complications?
• What are the major genetic diseases detected in fetuses?
• What are the appropriate technologies for the detection of aneuploidies, microdeletions, duplications, copy number variations and translocations?
• How far is genetic counselling important in educating pregnant women and healthcare professionals?
• What is the impact of recent advances in clinical genomics on genetic counselling?
• What different noninvasive and invasive prenatal screening tests are performed during a pregnancy?
• What are the detection rate, true positive rate and true negative rate for NIPTs?
• Currently, in which countries are the NIPTs available?
• What is the cost of NIPTs region-wise?
• What is the uptake of conventional maternal serum tests, NIPTs and invasive diagnostic tests in the U.S.?
• What is the average cost of maternal serum screening, NIPTs, fetal ultrasound screening and invasive diagnostic tests in the U.S.?
• What are the strategies to be adopted for clinical implementation of NIPTs for all pregnancies?
• What is the “patient directed model” for the integration of NIPTs into healthcare systems?
• How does the detection rate of NIPTs compare with the rates of conventional maternal serum screening tests?
• What are the genetic disorders detectable by different prenatal screening and diagnostic tests?
• What is the reliability of amniocentesis and CVS results?
• Is the future of invasive diagnostic tests uncertain?
• Do the intact fetal cells in maternal blood have use in noninvasive prenatal diagnosis (NIPD)?
• What about the use of trophoblast cells obtained from cervix in NIPD?
• How many genetic conditions are detected during newborn genetic screening in the U.S.?
• What is the status of newborn genetic screening in developed, developing and other countries?
• What are the different preimplantation genetic screening (PGS) and preimplantation genetic diagnosis (PGD)?
• What are the currently available PGS/PGD testing products available in the market?
• What are the currently used advanced technologies in prenatal, newborn and PGD testing?
• What is the global market for fetal ultrasound screening, through 2021?
• Who are the market leaders in fetal ultrasound systems?
• What is the global and regional market for prenatal screening by fetal MRI, through 2021?
• What is the global and regional market for maternal screening tests, through 2021?
• What is the global and regional market for NIPTs using cffDNA, through 2021?
• What is the global and regional market for invasive prenatal diagnostic tests, through 2021?
• What is the global and regional market for newborn screening tests, through 2021?
• What is the global market for newborn screening tests by technology, through 2021?
• What is the global and regional market for pre-implantation genetic diagnosis (PGD), through 2021?
• What is the global market for molecular diagnostics, through 2021?
• What is the global market for liquid biopsy tests, through 2021?
• What is the overall global market for personalized medicine diagnostics, through 2021?
• What is the overall global market for in vitro diagnostics (IVD), through 2021?
• What are the recent acquisition activities in prenatal screening industry?
• What are the important factors that drive the growth of prenatal & newborn genetic testing industry?
• What are the challenges faced by the prenatal screening industry?
• What are the possible future developments in prenatal screening industry?
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