Global 3D Cell Culture Market Research Report 2017 Analysis and Forecast to 2021

“”3D Cell Culture Global Market””
WiseGuyReports.com adds “3D Cell Culture Market 2017 Global Analysis, Growth, Trends and Opportunities Research Report Forecasting to 2021”reports to its database.

Executive Summary

3D cell culture is accepted as a new dimension of cell culture sector in biomedical research field. Cells grown on two-dimensional (2D) substrates do not represent true in-vivo cell environment and lack extracellular components, cell-cell and cell-matrix interactions necessary for differentiation, proliferation and cell-based functions. Hence, now-a-days three-dimensional (3D) cell culture methods are much preferred over 2D models as they provide a matrix support that encourages cells to organize into structures more indicative of the in–vivo environment and help to overcome 2D related shortcomings.Increased use of 3D cell culture systems bring the hope of lowering lead molecule attrition rates but however, these models restricts huge data reproducibility, challenge assay readout systems and do not contain all cells relevant for tumour environment. In addition, the favourable artificial environment created by 3D model enables longer-term dosing experiments for analyzing drug’s cumulative effects.

According to analysis, the 3D cell culture global market is poised to grow at a double digit CAGR to reach $3,702.2 million by 2021. The 3D cell culture market is classified based on types, applications, end-users and geography.

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The 3D cell culture by technology is segmented into scaffold based platform, scaffold free platform, bioreactors, microchips and hydrogels. Scaffold based platform is sub-segmented into natural scaffold, synthetic scaffold and hybrid composite. Natural scaffold is in-turn classified into protein based biomaterials (collagen, fibrin, silk, gelatin, elastin, keratin, actin and myosin, laminin and vitronectin) and polysaccharide based biomaterials (Agarose, alginate, hyaluronan, chitosan, amylase, dextran, cellulose and glycosaminoglycans). The synthetic scaffold is divided into polymer based biomaterials (Poly (lactic-co-glycolic acid), Polyethylene glycol, Polylactic acid, Polyglycolic acid, Polycapro lactone and polystyrene), peptide based biomaterials, ceramic based biomaterials (hydroxyapatite and bioactive glass) and metal based biomaterials (aluminium and titanium). 

Scaffold free platform is sub-divided into low attachment surface, hanging drop method and microfluidics. The bioreactors segment consists of spinner flask, rotating wall vessel and perfusion bioreactors. The 3D cell culture consumables section contains cells and tissues, media and sera and reagent. 

Further, the 3D culture market by application includes basic research, toxicity and drug safety screening, tissue engineering, stem cell research, drug discovery, gene therapy and cancer research. The 3D cell culture market is segmented into research laboratories and institutes, biotechnology and pharmaceutical industries, hospitals and diagnostic centers and others. 

Finally, the 3D cell culture market is classified by geographical regions into North America, Europe, Asia-pacific and Rest of the World.

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Table of Content:

1 EXECUTIVE SUMMARY 25 
2 INTRODUCTION 29 
    2.1 KEY TAKE AWAYS 29 
    2.2 REPORT DESCRIPTION 29 
    2.3 MARKETS COVERED 31 
    2.4 STAKEHOLDERS 33 
    2.5 RESEARCH METHODOLOGY 34 
      2.5.1 MARKET SIZE ESTIMATION 36 
      2.5.2 MARKET CRACKDOWN AND DATA TRIANGULATION 38 
      2.5.3 SECONDARY SOURCES 39 
      2.5.4 KEY DATA POINTS FROM SECONDARY SOURCES 40 
      2.5.5 PRIMARY SOURCES 41 
      2.5.6 KEY DATA POINTS FROM PRIMARY SOURCES 41 
      2.5.7 ASSUMPTIONS 41 
3 MARKET ANALYSIS 43 
    3.1 INTRODUCTION 43 
    3.2 MARKET SEGMENTATION 44 
    3.3 FACTORS INFLUENCING MARKET 46 
      3.3.1 DRIVERS AND OPPORTUNITIES 47 
          3.3.1.1 Rise in research and development investments 47 
          3.3.1.2 Rising need for organ transplantation 47 
          3.3.1.3 Use of 3D cell culture models as a tool against animal testing 48 
          3.3.1.4 Use of microfluidic technology 48 
          3.3.1.5 Increasing focus on regenerative medicine 49 
      3.3.2 RESTRAINTS AND THREATS 50 
          3.3.2.1 Lack of experienced and skilled professionals 50 
          3.3.2.2 Budget restriction for small and medium sized laboratories. 50 
          3.3.2.3 Lack of consistency in 3D cell culture products 50 
          3.3.2.4 Stringent process controls for advanced handling capabilities 51 
          3.3.2.5 Ethical concern over use of animal sources 51 
    3.4 REGULATORY AFFAIRS 52 
      3.4.1 UNITED STATES 52 
      3.4.2 EUROPE 53 
      3.4.3 INDIA 54 
      3.4.4 JAPAN 55 
    3.5 TECHNOLOGICAL ADVANCEMENTS 56 
      3.5.1 INTRODUCTION 56 
      3.5.2 ORGAN-ON-CHIP 56 
      3.5.3 3D BIOPRINTING 57 
      3.5.4 3D VASCULARIZED ORGANS 57 
      3.5.5 MIMETIX 3D CELL CULTURE SCAFFOLDS 58 
      3.5.6 NANO CULTURE PLATES 58 
    3.6 UPCOMING TECHNOLOGIES 59 
    3.7 APPROVED BIOMATERIALS 62 
    3.8 PORTER’S FIVE FORCE ANALYSIS 64 
      3.8.1 THREAT OF NEW ENTRANTS 65 
      3.8.2 THREAT OF SUBSTITUTES 65 
      3.8.3 BARGAINING POWER OF SUPPLIERS 65 
      3.8.4 BARGAINING POWER OF BUYERS 66 
      3.8.5 RIVALRY AMONG EXISTING COMPETITORS 66 
    3.9 MARKET SHARE ANALYSIS BY MAJOR PLAYERS 67

5 3D CELL CULTURE GLOBAL MARKET, BY APPLICATIONS 134 
    5.1 INTRODUCTION 134 
    5.2 BASIC RESEARCH 137 
    5.3 TOXICITY AND DRUG SAFETY SCREENING 139 
    5.4 TISSUE ENGINEERING 141 
    5.5 STEM CELL RESEARCH 143 
    5.6 DRUG DISCOVERY 145 
    5.7 CANCER RESEARCH 147 
    5.8 GENE THERAPY 149 
6 3D CELL CULTURE GLOBAL MARKET, BY END USERS 151 
    6.1 INTRODUCTION 151 
    6.2 ACADEMIC INSTITUTES 154 
    6.3 BIOTECHNOLOGY AND PHARMACEUTICAL INDUSTRIES 156 
    6.4 HOSPITALS AND DIAGNOSTIC CENTERS 158 
    6.5 OTHERS 160 
7 REGIONAL ANALYSIS 162 
    7.1 INTRODUCTION 162 
    7.2 NORTH AMERICA 165 
    7.3 EUROPE 175 
    7.4 ASIA-PACIFIC 185 
    7.5 REST OF THE WORLD 195 
8 COMPETITIVE LANDSCAPE 205 
    8.1 INTRODUCTION 205 
    8.2 NEW PRODUCT LAUNCHES 207 
    8.3 AGREEMENTS, PARTNERSHIP, COLLABORATION & JOINT VENTURES 215 
    8.4 EXPANSIONS, APPOVALS AND SERVICE LAUNCHES 221 
    8.5 MERGERS & ACQUISITIONS 222 

 

LIST OF TABLES

TABLE 1 3D CELL CULTURE GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 28 
TABLE 2 3D CELL CULTURE GLOBAL MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 71 
TABLE 3 3D CELL CULTURE TECHNOLOGY GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 74 
TABLE 4 3D CELL CULTURE TECHNOLOGY GLOBAL MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 75 
TABLE 5 3D CELL CULTURE SCAFFOLD BASED PLATFORM GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 77 
TABLE 6 3D CELL CULTURE SCAFFOLD BASED PLATFORM GLOBAL MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 78 
TABLE 7 3D CELL CULTURE NATURAL SCAFFOLDS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 81 
TABLE 8 3D CELL CULTURE SYNTHETIC SCAFFOLDS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 89 
TABLE 9 3D CELL CULTURE HYBRID COMPOSITE SCAFFOLDS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 97 
TABLE 10 3D CELL CULTURE SCAFFOLD FREE PLATFORMS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 99 
TABLE 11 3D CELL CULTURE SCAFFOLD FREE PLATFORMS GLOBAL MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 100 
TABLE 12 LOW ATTACHMENT SURFACE SCAFFOLD FREE PLATFORMS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 103 
TABLE 13 HANGING DROP METHOD SCAFFOLD FREE PLATFORMS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 105 
TABLE 14 MICROFLUIDICS SCAFFOLD FREE PLATFORMS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 107 
TABLE 15 3D CELL CULTURE BIORECTORS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 109 
TABLE 16 3D CELL CULTURE BIOREACTORS GLOBAL MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 110 
TABLE 17 3D CELL CULTURE SPINNER FLASK BIOREACTORS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 112 
TABLE 18 3D CELL CULTURE ROTATING WALL VESSEL BIOREACTORS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 114 
TABLE 19 3D CELL CULTURE PERFUSION BIOREACTORS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 116 
TABLE 20 3D CELL CULTURE MICROCHIPS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 118 
TABLE 21 3D CELL CULTURE HYDROGELS GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 120

TABLE 22 3D CELL CULTURE CONSUMABLES GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 121
TABLE 23 3D CELL CULTURE CONSUMABLES GLOBAL MARKET REVENUE, BY TYPE, (2013-2021) ($MN) 122 
TABLE 24 3D CELL CULTURE CELLS AND TISSUE CONSUMABLES GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 125 
TABLE 25 3D CELL CULTURE MEDIA AND SERA CONSUMABLES GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 128 
TABLE 26 3D CELL CULTURE MICROPLATE AND REAGENT CONSUMABLES GLOBAL MARKET REVENUE, BY REGION, (2013-2021) ($MN) 131

…CONTINUED

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