As one of the world’s largest producers of synthetic peptides, Creative Peptides announced the launch of neoantigen peptides vaccine synthesis service for both academic and industrial community on March 22, 2018, adding to its already existing services like custom peptide synthesis, process development, GMP manufacturing as well as catalog products.
Neoantigens is a class of HLA-bound peptides that arise from tumor-specific mutations. They are highly immunogenic because they are not present in normal tissues, thus can be used as biomarkers to differentiate cancer cells from normal ones. Such recognition of these individual-specific neoantigens could very possibly open a new door for cancer immunotherapy.
“Several clinical studies indicated that vaccination with neoantigens could both expand pre-existing neoantigen-specific T-cell populations and induce a broader repertoire of new T-cell specificities in cancer patients. This finding brings great hope for people suffering from cancer,” says Dr. Robert Martinez, head of Creative Peptides’ synthesis businesses. “Since these neoantigen peptides are patient specific, developing personalized vaccine would target cancer cells of an individual specifically and effectively.”
Another point is that producing vaccines containing multiple individual-specific neoantigens can minimize the chance of tumor escape by loss of antigen.
Equipped with cGMP certified manufacturing facilities and more than 20 years of expertise, Creative Peptides offer the following neoantigen peptides vaccine synthesis services:
• DNA and RNA sequencing of peripheral blood mononuclear cells of a cancer patient for detection of tumor-specific mutations.
• Translation of these mutations to human leukocyte antigen (HLA) molecules.
• Prediction of personalized peptides with high affinity binding to HLA molecules.
• Manufacture of personalized vaccine with pools of these synthetic personalized peptides.
“We believe that with advantages of good services, Creative Peptides is able to offer various research peptides from milligram to multi-kilogram and at competitive price. Fast delivery are guaranteed in that many of our API peptides are in stock. Also, personalized consultation with experienced peptide experts is available,” further adds Dr. Robert Martinez.
About Creative Peptides
With over a dozen of years’ unremitting efforts in the pharmaceutical industry, Creative Peptides has achieved considerably in not only providing a comprehensive collection of research peptides, cosmetic peptides, but also offering related services like custom peptide synthesis, chiral synthesis, cell penetrating peptides synthesis, etc. With the advantage of world-class scientific teams consisting of experts in multiple fields like peptide technology, antibodies as well as synthetic chemistry, Creative Peptides now focus more on satisfying different needs of customers and a series of measures are to be taken in the near future.
Company Name: Creative Peptides
Contact Person: Caroline Miller
Email: Send Email
Address:45-16 Ramsey Road
Country: United States