Oligonucleiotide Synthesis Market Size, Share, Growth, Trends Market Benefits, Business Opportunities & Future Investments 2025

Oligonucleotides synthesis is defined as building up smaller chunks of nucleic acid artificially with the help of enzyme chemistry and genetic engineering. These chemically synthesized oligonucleotides are composed of defined chemical structures or sequences in various sizes. They are typically made up of 13 to 25 nucleotides and are constructed to incorporate particularly to DNA or RNA sequences.

Oligonucleotide Synthesis: blocks of nucleic acid assist in research, diagnostic and therapeutic purposes 

Market Overview

According to a new report published by Reports Monitor titled, “Oligonucleotide Synthesis Market by Component, Application, and End-User: Global Opportunity Analysis and Industry Forecast, 2017–2025,” the Oligonucleotide Synthesis market was valued at XX million in 2016, and is projected to reach at XX million by 2025, growing at a CAGR of XX% from 2017 to 2025. 

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Oligonucleotide synthesis is referred to construction of nucleic acids such DNA and RNA  with specific chemical structure or sequences. Oligonucleotides are predominantly used in laboratory applications such as diagnostic, therapeutic, research & development as well as industrial and academic. They are applied since initial research and screening until target validation and drug development. Forward movement made in recent years in contemporary solid phase based synthesis technologies have made possible the synthesis of automated high-through-put custom oligonucleotide. 

Growing usage of synthesized oligonucleotides in molecular diagnostics and in clinical application as well as increasing emphasis on genetics & genomics has led the oligonucleotide synthesis market to propel in last couple of years. Moreover, successive improvements in synthesis procedures, amplification and automation have entirely transformed biological research leading the market to grow further.  In addition, rising expenditure on R&D, increasing government investment and rise in venture capital funding is fuelling the growth of the market. 

However, lack of consolidated set of guidelines for therapeutic oligonucleotides and price erosion of synthesized oligonucleotides may restraint the growth of the market.  Swiftly growing healthcare sector leveraging oligonucleotides in research, therapeutics and diagnostics, huge investment by pharma and biotech companies and existence of key market players strongly supports the growth of the market in North America. 

The global oligonucleotide synthesis market is segmented on the basis of product, application, end-user and region. Based on product type the market is differentiated into synthesized oligonucleotides, reagents and equipment’s. Synthesized oligonucleotides are further divided into primers, probes, linkers & adopters. Application wise the market is categorized into research, diagnostics and therapeutics. 

Research is further separated into Sequencing, PCR, OPCR, gene synthesis and others. Therapeutics is segmented into nucleic acid aptamers, RNAi, DNA/antisense oligonucleotide and immunotherapy applications. Depending upon end-user the market is classified into pharmaceutical & biotechnological companies, diagnostic laboratories, academic research institutes and other end-users.  

Competitive Analysis

The global market for oligonucleotide synthesis appears to be highly fragmented in terms of competition. Partnership, product launch, and channel integration are some of the other strategies adopted by market players. Major players in the market of oligonucleotide synthesis are Sigma-Aldrich Corporation Thermo Fisher Scientific, Integrated DNA Technologies, Agilent Technologies, GE Healthcare, BioAutomation, Eurofins Genomics, GeneDesign, Eurogentec and GenScript.

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In December 2016, Ajinomoto Co., Inc. acquired all shares of a major Japanese contract development and manufacturing organization GeneDesign, Inc. The company primarily engages nucleic acid drug production. After this acquisition Ajinomoto Co. has planned to create collaborations in order to accelerate expansion of the oligonucleotide manufacturing technologies and pharmaceutical manufacturing capabilities.  

Research Scope

The study for Global Oligonucleotide Synthesis Market will provide market size, estimates and forecast based on the following years:

Historic data: 2015 Base Year Estimate: 2016 Forecast: 2017 to 2025

The report has been categorized in two distinctive sections, where the first category titled as Market Overview provides a holistic view of the market, key trends, drivers, challenges/restraints or opportunities with their current and expected impact on the overall industry sales.

Our analyst implement several qualitative tools such as Ansoff’s Matrix, PESTEL analysis, Porter’s five force analysis among other to interpret and represent key industry findings.

The second section of the study provides market size, estimates and forecast for key market segments and regional market. The final part of the report highlights key manufacturers/vendors operating in the associated market.

1. Introduction

1.1. Market Definition

1.2. Market Scope

2. Research Methodology

2.1. Primary Research

2.2. Secondary Sources

2.3. Assumptions & Exclusions

3. Market Overview

3.1. Research Report Segmentation & Scope

3.2. Key Market Trend Analysis

3.2.1. Market Drivers

3.2.2. Market Restraint/Challenges

3.2.3. Market Opportunities

3.3. Porter’s Five Forces Analysis

3.4. Potential Venture Avenues

3.5. Market Share Analysis, 2016 

4. Product Overview

4.1. Introduction

4.2. Market Size & Forecast, 2015 to 2025

4.2.1. Synthesized Oligonucleotides Product Primers Probes Linkers & Adopters

4.2.2. Reagents

4.2.3. Equipment

(Note: The segments mentioned above are tentative in nature and are subject to change as the research progresses)

5. Application Overview

5.1. Introduction

5.2. Market Size & Forecast, 2015 to 2025

5.2.1. Research Sequencing PCR qPCR Gene Synthesis

5.2.2. Diagnostics

5.2.3. Therapeutics Nucleic Acid Aptamers RNAi DNA/Antisense Oligonucleotide Immunotherapy Applications

(Note: The segments mentioned above are tentative in nature and are subject to change as the research progresses)

6. End-User Overview

6.1. Introduction

6.2. Market Size & Forecast, 2015 to 2025

6.2.1. Pharmaceutical & Biotechnological Companies

6.2.2. Diagnostic Laboratories

6.2.3. Academic Research Institutes 

6.2.4. Other End-Users

(Note: The segments mentioned above are tentative in nature and are subject to change as the research progresses)

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