New York, US – July 24, 2018 – Creative Biolabs, a world-leading biotech company occupied in antibody-drug conjugates, released two high-quality ADC Toxins including podophyllotoxin and polyketomycin.
Antibody-drug conjugates (ADCs) inherit high specificity and affinity towards well-defined targets from monoclonal antibodies and more remarkably, expand the therapeutic window of the conjugated drugs (payloads), which are usually highly toxic and diverse in their biochemical nature.
ADC toxins target crucial intracellular pathways to induce cell death and they can be over 1000-fold more potent than chemotherapeutic agents. Based on the original and highly effective DrugLnk service platform, Creative Biolabs is capable of offering a large collection of highly potent toxins and toxin derivatives targeting a variety of cellular pathways, including but not limited to podophyllotoxin and polyketomycin for antibody drug conjugate (ADC) development.
Podophyllotoxin is a potent inhibitor of microtubule assembly an DNA topoisomerase II
· Classification: Microtubule Inhibitors
· Cat. No: ADC-P-126
· CAS NO: 518-28-5
· Molecular Weight: 414.41
· Purity: 95%
Polyketomycin is a tetracyclic quinone glycoside that shows antibacterial, antimalarial and antitumor activity.
· Cat. No: ADC-P-127
· CAS NO: 200625-47-4
· Classification: Others
· Molecular Weight: 864.9
· Purity: 95%
Meanwhile, Creative Biolabs also provides microtubule assemble and dynamics (microtubule toxins), DNA biochemistry and structure (DNA toxins), and gene transcription (transcription toxins) for global clients. The toxins from Creative Biolabs are of high purity (>95%) and defined structure as often characterized by LC-MS and 1HNMR.
With professional Ph.D. level scientists and over a decade of experience in antibody-drug conjugates, Creative Biolabs is dedicated to serve our clients the best suitable toxins in terms of their unique needs in ADC development projects by providing customized services that are tailored to meet your R&D timeline and budget.
About Creative Biolabs
Established in 2004, Creative Biolabs is highly specialized in advanced antibody biochemistry and engineering. With more than a decade of exploration and expansion, our current research and service capacity covers the entire new drug discovery and development pipeline, ranging from early discovery, pre-clinical evaluations, cGMP manufacturing, to clinical trials. As an international cooperation, we have established offices all around the globe with more than 200 well-trained full-time scientists and technicians, who work closely with our customers and research partners to develop new medicines for a better, healthier world.
Company Name: Creative Biolabs
Contact Person: Bella Smith
Email: Send Email
Address:45-1 Ramsey Road
State: New York
Country: United States