SHIRLEY, NY, UNITED STATES – Feb 18, 2018 – Creative Proteomics, an integrated CRO company that provides a full range of drug development services, announces that it has improved its five services related to proteomics bioinformatics. With years of experience and advanced experiment equipment, the scientists in Creative Proteomics are confident to provide premier proteomics bioinformatics services to customers. The products in the great upgrade include functional annotation and enrichment analysis, clustering analysis, network analysis, statistical analysis and proteomic analysis of post-translational modifications.
Functional annotation is the process of attaching biological information to a gene or protein sequence. The basic level of annotation is to use the sequence alignment tool BLAST to find similarities and then annotate genes or proteins based on that. As many genomes are sequenced, computational annotation methods are becoming increasingly important to characterize genes and proteins from their sequences. Functional enrichment analysis is a method of determining the classes of genes or proteins that are over-expressed in a large group of genes or proteins and may be associated with a disease phenotype. This method uses statistical methods to determine significantly enriched genomes. In GSEA, DNA microarrays or RNA-Seq are still performed and compared between two different categories, but in a long list focus on gene sets rather than individual genes. Currently, functional annotation and enrichment analysis have been widely used in bioinformatics of omics research.
In data mining of bioinformatics, clustering analysis is used to classify a set of observations into two or more mutually exclusive unknown groups based on a combination of interval variables. The goal is to discover a system in which observations, usually genes and proteins, are organized into groups, where members of the group share properties in common. Creative Proteomics can use a typical set of clustering methods, algorithms, and applications to interpret the data you collect, including partitioning methods such as k-means, layered methods, and density-based methods.
Network analysis services have also widely used in bioinformatics research, as are statistical analysis. Correlation networks facilitate network-based gene screening methods that can be applied to identify candidate biomarkers or therapeutic targets. Statistical analysis is the study of the collection, organization, examination, summarization, manipulation, interpretation and presentation of quantitative data. It handles all aspects of data, including data collection planning based on surveys and experimental designs. Statistical analysis is part of the data analysis. The purpose of statistical analysis is to determine trends.
Post-translational modification (PTM) refers to the covalent and usually enzymatic modification of proteins during or after protein biosynthesis. PTMs play an important role in many cellular processes. Living cells are constantly exposed to environmental stimuli and must adapt to rapidly changing conditions. Due to the large static nature of the genome, highly dynamic and well-regulated systems are required to maintain cellular homeostasis. Through proteomic analysis of post-translational modifications, a variety of different protein species can be produced, compensating for the inconsistency between a relatively low number of coding genes and the large number of variable modulators required in complex organisms.
“Creative Proteomics is committed to providing high-quality services and products to laboratories and research institutes. Our improved proteomics bioinformatics services are customized to meet the needs of our customers who believe in our scientists and creative proteomics”, said Dr. Charlie.
About Creative Proteomics
Creative Proteomics, as an experienced proteomics, metabolomics, and bioinformatics services supplier, has been well equipped with advanced technologies, in order to meet the increasing needs from researchers and scientists in their proteomics and metabolomics related researches.
Company Name: Creative Proteomics
Contact Person: Dora West
Email: Send Email
Address:45-1 Ramsey Road
State: New York
Country: United States