New York – February 28, 2019 – Creative Biolabs, a service provider of innovative and sophisticated bispecific antibody (BsAb) development services, now releases cost-efficient bispecific antibody (BsAb) sequencing services tailored to customer’s exact needs.
BsAbs refer to artificially designed molecules that enable simultaneously identify two or more different antigens, reportedly applied in guiding effector cells to disease cells, targeting disease pathway, blocking cytokines/receptors, etc.
At the beginning of BsAb development, Creative Biolabs can offer customized BsAb design and experimental workflows based on target, applications and MOA, either for fundamental research or clinical trials. Then BsAb engineering services are provided to adjust their properties including size, valency, flexibility, half-life, biodistribution, etc., or other specific requirements. For BsAbs manufacturing, genetic engineering, hybrid-hybridoma technology, chemical conjugation are three practical strategies to develop BsAbs and achieve large-scale generation. In addition, BsAb analysis services of basic and clinical research, such as biochemistry characterization, pharmacokinetic analysis, stability analysis, preclinical research functional analysis, can be customized for further developing.
The antibody expert in Creative Biolabs added, “Besides the comprehensive list of BsAbs development services, we also provide high-precision bispecific antibody sequencing services on the basis of database assisted shotgun sequencing (DASS) technology. We make use of a high-field facility (Orbitrap Elite hybrid MS) with 240.000 resolution.
“With years of experience and our complete BsAb Sequencing Platform, we can guarantee sequence validation results in the first attempt and at least 5 folds coverage for the complete V(D)J-region. Our mapping algorithm has error tolerance that could reliably match the “mutated” peptides to the corresponding germline. The system generates quantities of overlapping peptides during the fragmentation process, enabling to sequence long chains. Meanwhile, most isobaric amino acid combinations can be distinguished by our techniques. For instance, W can be differentiated from GE, AD, and SV by mass accuracy.”
Creative Biolabs can help clients with BsAbs development when there is no record of amino acid sequences of specific antibody in database, and ensure superb accuracy with almost no risk to get real sequencing result, a fast turn-around time within 10 working days, and 100% powerful coverage for the VJ and VDJ region. More detailed information in any BsAb format from any species (mouse, rat, rabbit, llama, etc.) can be found at https://www.creative-biolabs.com/bsab.
About Creative Biolabs
Creative Biolabs was established in 2004 by scientists who are dedicated to conquering of cancer. Over the past 10 years, Creative Biolabs has grown into a recognized world leader in antibody (rAb) discovery, engineering, production, and analysis. Standing on the shoulder of a giant, the bispecific antibody (BsAb) team has a collective of experienced scientists committed to providing high-quality services to customers all over the world. Now, with the cutting-edge platforms and methods (quadroma development, chemical conjugation, and genetic engineering), a comprehensive list of bispecific antibody products is available to customers in academia and industry fields.
Company Name: Creative Biolabs
Contact Person: Candy Swift
Email: Send Email
Address:45-1 Ramsey Road
State: New York
Country: United States