New York, July 01, 2019 Creative Biolabs, one of the most highly respected vaccine testing laboratories, now provides a comprehensive vaccine preclinical assay to help clients through the assessment stages of development with excellent GLP reproductive toxicology studies.
Vaccine preclinical assay is a highly efficient approach that assesses the potency and safety of human vaccines, and offers valuable information on the availability of appropriate animal models during vaccine development. For studying disease pathogenesis, host-pathogen interactions and protection mechanisms after vaccination, infections or disease treatment, Creative Biolabs offers natural and surrogate animal models, in which natural disease models help understand the immunopathogenesis, analyze the virulence factors and their roles in invasion, penetration, and toxicity as well as host’s immune responses to pathogens, while surrogate models provide a useful tool for studying specific aspects of disease pathogenesis and host immune response.
In order to detect any potential reproductive toxicology of all components contained in the vaccine including antigens, vehicles, preservatives, and adjuvants, Creative Biolabs also offers a series of GLP reproductive toxicology studies according to internationally recognized guidelines, which plays a significant role to determine the risk of the test vaccines to humans by integrating the investigations and the interpretation of the results and other pharmacological and toxicological data, including:
- Female reproduction: Oogenesis (histology), menstrual cyclicity, endocrine status (LH, FSH, CG, prolactin, estrogens, progesterone, androgens, inhibins), and fertility;
- Male reproduction: Spermatogenesis (histology, daily sperm production, spermatogenic stages), sperm maturation, semen parameters, testis size/biopsy, endocrine status (LH, FSH, prolactin, estrogens, progesterone, androgens, inhibins), prostate status, and fertility;
- Developmental toxicity (embryo-fetal development);
- Pre- and post-natal development toxicity studies;
- Multigenerational studies.
As one of the most leading vaccines service provider, Creative Biolabs dedicates itself to enlightening the long and grueling path of vaccine development through a series of in vivo assays. Experts in Creative Biolabs with over 10 years of experience are enough competent to customize the best services at a competitive price with a fast turnaround time. More information can be reached at https://www.creative-biolabs.com/vaccine/.
Creative Biolabs, headquartered in New York, is a leading custom service provider in the field of vaccine development, preclinical assessment and GMP manufacturing. The technical and regulatory experts can provide vaccine developers with a full range of products and vaccine related services. Traditional and the most updated genetic engineering technologies are combined to efficiently produce highly immunogenic and safe vaccines to address emergency unmet medical needs. The service portfolio includes a full range of vaccine design for client’s specific requirements that covers vaccine target validation, vaccines targeting bacterial, viral, fungal, parasites, cancer markers and more. Formulation optimization services are also available for maximum potency, including improving delivery systems, a great variety of adjuvant products and services like PRR Ligands scanning and adjuvants synthesis.
Company Name: Creative Biolabs
Contact Person: Candy Swift
Email: Send Email
Address:45-1 Ramsey Road
State: New York
Country: United States