New York, USA – August 26, 2019 – As a professional provider occupied in the antibody field for over 10 years, Creative Biolabs is committed to offering highly efficient bispecific antibodies (BsAbs) for industrial and scientific clients all round the world for the BsAbs applications in Oncology, Immunology, Diagnostics, Gene Therapy, Hematology, Ophthalmology, and Osteology.
As engineered macromolecules with two or more distinct binding specificities within one molecule, bispecific antibodies are mostly known for its application in cancer treatment by interfering with signaling pathways, redirecting cytotoxic immune cells, or delivering radioactive therapeutics, most of which act through T cell recruitment and NK cell recruitment, designed to bind tumor-associated antigens and CD3 or CD16/CD56. As an experienced antibody expert, Creative Biolabs is capable of offering BiTE, Triomab, DART, TandAb, and Tandem scFv-Fc BsAb in oncology to block a signaling pathway and its backup pathway, or one pathway at two points.
The ability of BsAbs to interfere with more than one receptor or ligand in one or two pathways at the same time make a huge difference in avoiding immune escape mechanisms and increasing drug efficacy. Therefore, bispecific antibodies also play a significant role in the treatment of common immune diseases, such as rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, Behcet’s disease, psoriasis, inflammatory bowel disease, allergy, and cardiovascular diseases. The superior BsAb production platforms in Creative Biolabs guarantee customers to develop or provide high-quality BsAbs for immune disease within a fast-turnaround time and a satisfying budget.
On the other hand, bispecific antibody also shows a promising effect in the field of gene therapy, developed as an adapter molecule to recognize the vector and a specific marker on target cell surface, insuring against modification of the virus and disruption of vector assembly, stability, or activity. Scientists in Creative Biolabs are able to develop genetic, biological and chemical methods for BsAb engineering in immunology, and have established a comprehensive target cell-BsAb-vector system to deliver any other therapeutic gene to the target cell.
As for BsAbs diagnostic applications such as immunoassays, radioimmunodiagnosis, and immunohistochemistry, BsAbs can help researchers obtain a more sensitive, rapid and specific detection while avoiding batch to batch variations in a simpler process. Comparing to conventional reagents, BsAbs have unique advantages that ensure a precise ratio of antibody to detection moiety and the uniformity of the products. Also, BsAbs for diagnostic applications are purified along with tagging, which simplifies the production procedure. With an in-depth knowledge reverse, the team at Creative Biolabs can provide customers versatile bispecific antibodies with higher sensitivity and reproductively.
About Creative Biolabs
Creative Biolabs was established in 2004 by scientists who are dedicated to conquering of cancer. Over the past 10 years, Creative Biolabs has grown into a recognized world leader in antibody (rAb) discovery, engineering, production, and analysis. Standing on the shoulder of a giant, the bispecific antibody (BsAb) team has a collective of experienced scientists committed to providing high-quality services to customers all over the world. Now, with the cutting-edge platforms and methods (quadroma development, chemical conjugation, and genetic engineering), a comprehensive list of bispecific antibody products is available to customers in academia and industry fields.
Company Name: Creative Biolabs
Contact Person: Candy Swift
Email: Send Email
Address:45-1 Ramsey Road
State: New York
Country: United States