New York, US, August 29 Creative Biolabs, an outstanding service provider in the field of T cell immunotherapy development, releases comprehensive TAC Engineered T Cell Development Services from discovery to commercialization based on the proprietary CellRapeutics™ T Cell Antigen Coupler (TAC) Technology.
Over these years, T cell immunotherapy has been a hot topic that attracts extensive attention from either academic researchers or biological companies, of which T cell antigen coupler (TAC) technology emerged as one of the most highly effective methods that overcomes the conventional limitations of chimeric antigen receptor and T cell receptor technolog
y with a more effective induction of anti-tumor response and a reduction of toxicity.
For the sake of a shorter turnaround time and a lower drug development cost, scientists specialized in TAC technology at Creative Biolabs focus on developing a comprehensive list of TAC Engineered T Cell Development Services, covering the whole process from biomarker identification to in vitro assays.
1 TAC Biomarker Identification & Selection
Experts with years of experienced in Creative Biolabs can provide global clients with a full list of services to target immunogenic epitope, thereby identifying and selecting the biomarkers of T Cell receptor Antigen Coupler in different disease, such as liquid tumors, solid tumors, and autoimmune diseases. The target antigen will bind and interact with the TAC antigen binding domain, expressed at high levels by most of tumor cells to trigger sufficient immune response.
2 TAC Generation & Optimization
For TAC generation and optimization, which plays an important role in TAC-T cell development, Creative Biolabs can provide multiple approaches to generate TACs that are specific for the antigens expressed by a wider variety of disease-associated cell types, reducing the potential toxicities and enhancing the treatment effect, by redirecting T cells in a TCR-dependent, MHC-independent manner.
3 TAC Design & Construction
A standard TAC consists of an antigen-binding domain, T cell receptor recruiting domain, and co-receptor domain, in which each domain can be designed by Creative Biolabs to utilize a variety of proteins, allowing the T cell antigen coupler to be modified for a more efficient response to a large number of different antigens.
4 TAC In Vitro Assay
A wide range of in vitro assays are available in Creative Biolabs to evaluate the safety and efficacy of TAC-T cells, including cytokine level analysis services with high-quality animal models, in vitro cytotoxicity assays for detecting the cell viability and cytotoxicity, T cell activation services to monitor the proliferation and differentiation. At the same time, a panel of state-of-art technologies have been established to support the above assays, including but not limited to enzyme-linked immunosorbent assay (ELISA) and polymerase chain reaction (PCR) as well as flow cytometry (FCM).
The client-focused team from Creative Biolabs is capable of customizing a detailed drug development plan in terms of each unique need of clients. More information can be reached at https://www.creative-biolabs.com/tac-t.
About Creative Biolabs
Creative Biolabs was founded by scientists who are dedicated to the conquering of cance and believe that building up a custom-service-centered business model is important for optimizing the drug development process, leveraging accessible resources, and forming a team of various background to conduct drug discovery in future. Creative Biolabs provides a comprehensive, high-quality, single-source value chain from discovery to commercialization in T cell antigen coupler (TAC) technology. As a research-driven and customer-focus company, Creative Biolabs is dedicated to helping worldwide customers shorten the discovery and development time as well as lower the cost of T cell antigen coupler (TAC) development process.
Company Name: Creative Biolabs
Contact Person: Candy Swift
Email: Send Email
Address:45-1 Ramsey Road
State: New York
Country: United States