(Albany, US) DelveInsight has launched a new report on Acute Heart failure Epidemiology
DelveInsight’s ‘Acute Heart failure (AHF) – Epidemiology Forecast to 2030′ report delivers an in-depth understanding of the disease, historical and forecasted Acute Heart failure (AHF) epidemiology in the 7MM, i.e., the United States, EU5 (Germany, Spain, Italy, France, and the United Kingdom), and Japan.
Heart Failure (HF), also known as congestive HF, is bifurcated as left-side HF (when the heart is unable to pump enough oxygen in the blood to the body) and right-side HF (when the heart is unable to fill itself with enough blood). Acute heart failure (AHF) is broadly defined as a rapid onset of new or worsening signs and symptoms of HF. It is often a potentially life-threatening condition requiring hospitalization, and emergency treatment aim to manage fluid overload and hemodynamic compromise. This umbrella term includes patients presenting for the first time with typical symptoms and signs of heart failure (de novo AHF) and those with worsening of their pre-existing cardiomyopathy (acute decompensated heart failure).
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Acute Heart failure Epidemiology
A less common precipitant to AHF is one of a several possible non-ischemia myocardial insults. This includes the onset of acute myocardial dysfunction with inflammatory insults, toxic insults, and insults of an undefined nature such as peripartum cardiomyopathy. Admission to hospital with AHF can often herald a diagnosis of chronic HF as these acute insults may have long-term sequelae on myocardial function. Acute HF severity can be measured using known predictors of poor outcome, such as hypotension, renal dysfunction, hyponatremia, elevated biomarkers, respiratory distress, or concomitant comorbidities. The large majority of patients presenting with AHF do so in the context of pre-existing cardiomyopathy, a situation described as acute decompensated heart failure (ADHF). There are several key differences between this group of patients and those presenting with de novo AHF. Unlike with de novo AHF, patients with ADHF tend to present with signs and symptoms of congestion and fluid retention (weight gain, exertional dyspnea, orthopnea, dependent edema) rather than with pulmonary edema or cardiogenic shock that characterize acute LV systolic dysfunction.
Acute Heart failure Key facts
- The study conducted by Farmakis et al. (2015) found that the patients admitted for AHF were aged >70 years, and about half of them are male. Most have a previous history a heart failure, while de novo AHFrepresents only one-fourth to one-third of cases. About 40–55% have preserved LVEF (left ventricular ejection fraction).
- In terms of noncardiovascular comorbidities, about 40% of patients admitted for AHF have a history of diabetes mellitus, about one-fourth to one-third have renal dysfunction and chronic obstructive pulmonary disease, while anemia was also present in 15–30% of patients. Bouee et al. (2014) described the incidence and profile of patients hospitalized for acute heart failure (AHF) and found that incidence rates were 2.28‰ in 2006 and 2.45‰ in 2010. The proportion of patients aged ≥75 increased from 71.0% in 2006 to 74.3% in 2010. Half of the patients were male. The mean number of comorbidities was 9.6 in 2010. Gender-specific Epidemiology of Acute Heart Failure (AHF)
- In a study by Tavazzi et al. (2006), it was found that out of total selected patients, 44% patients were diagnosed as having de novo acute HF, and 56% had worsening chronic HF. An ejection fraction (EF)>40% was found in 34% of cases.
- The study by Kurmani et al. (2017) found that 20–30% of patients with ADHF had an element of renal dysfunction, and 40% have diabetes mellitus.
Acute Heart failure Report Scope
- The Acute Heart failure (AHF) report covers a detailed overview explaining its causes, symptoms, classification, pathophysiology, diagnosis and treatment patterns
- The Acute Heart failure (AHF) Epidemiology Report and Model provide an overview of the risk factors and global trends of Acute Heart failure (AHF) in the seven major markets (7MM:US, France, Germany, Italy, Spain, UK, and Japan)
- The report provides insight about the historical and forecasted patient pool of Acute Heart failure (AHF) in seven major markets covering the United States, EU5 (Germany, Spain, France, Italy, UK), and Japan
- The report helps to recognize the growth opportunities in the 7MM with respect to the patient population
- The report assesses the disease risk and burden and highlights the unmet needs of Acute Heart failure (AHF)
- The report provides the segmentation of the Acute Heart failure (AHF) epidemiology
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Table of content
1. Key Insights
2. Executive Summary of Acute Heart failure (AHF)
3. Acute Heart failure (AHF): Disease Background and Overview
4. Patient Journey
5. Epidemiology and Patient Population
6. Treatment Algorithm, Current Treatment, and Medical Practices
7. KOL Views
8. Unmet Needs
10. DelveInsight Capabilities
12. About DelveInsight
Why should you buy this report?
- The Acute Heart failure (AHF) Epidemiology report will allow the user to –
- Develop business strategies by understanding the trends shaping and driving the global Acute Heart failure (AHF) market
- Quantify patient populations in the global Acute Heart failure (AHF) market to improve product design, pricing, and launch plans
- Organize sales and marketing efforts by identifying the age groups and sex that present the best opportunities for Acute Heart failure (AHF) therapeutics in each of the markets covered
- Understand the magnitude of Acute Heart failure (AHF) population by its epidemiology
- The Acute Heart failure (AHF) Epidemiology Model developed by DelveInsight is easy to navigate, interactive with dashboards, and epidemiology based with transparent and consistent methodologies. Moreover, the model supports data presented in the report and showcases disease trends over 11-year forecast period using reputable sources
- Acute Heart failure Market Insights, Epidemiology and Market Forecast-2030
- Acute Heart failure (AHF) Pipeline Insight, 2020
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