New York, USA – December 24, 2020 – The achievement by far of PROTAC based drugs can never be separated from the discovery of how cells clean up abnormal proteins, i.e., the protein degradation process regulated by Ubiquitin, which was awarded the Nobel Prize in Chemistry in 2004. PROTAC drug, as a novel therapeutic method with great potentials, has brought molecular drugs back to the stage. Creative Biolabs, keeping pace with the technology breakthroughs and foreseeing the great potentiality of PROTAC technology, spent years of energy optimizing the procedures of PROTAC discovery and development, and built a team of scientists specialized in this field to offer professional support.
At the PROTAC solution center, professional services are offered, which can not only turn the concept about the desired PROTAC molecule into reality but also comprehensively evaluate a PROTAC molecule that is either provided by the customers or comes from the delivered result. There are three main streams, among which PRTAC molecule discovery is the most popular among lab researchers, which covers ligand design & screening, linker design & optimization, and structural modification.
Creative Biolabs initiates a PROTAC discovery project when an agreement is received after a professional consultation and an exhausting proposal. It all starts with ligand design to determine the target protein of interest. There are available ligand products and customized design solutions to meet the project target. Another crucial component of a PROTAC molecule is the linker, of which the length and position can be modified by Creative Biolabs to achieve efficient ubiquitination of the target protein and its ultimate degradation. The peptide and compound synthesis is quite a flexible offering that the technicians can conduct synthesis operations on part of or all of the materials provided by the clients, or on the in-list products, or on the delivered outcomes from other customized solutions.
The PROTAC based molecular drug is showing great potentials because it has several advantages over traditional drugs, which are lower dosage, reduced toxicity, prolonged pharmacodynamics effect, etc. Recent breakthroughs in this field also push forward the financial investment on the market. With climbing numbers of researchers joining the field of PROTAC, Creative Biolabs is receiving mounting numbers of inquiries.
More details about the technical capabilities are available at https://www.creative-biolabs.com/protac.
Creative Biolabs is a biotechnology solution provider, which is specialized in small molecule development and engineering, offering one-stop solutions to worldwide customers from pharmaceutical companies, research institutes, and universities. Creative Biolabs is open to global cooperations to pass on its specialties. All of the services and products are offered in the manner determined by the customers. After years of exploration, it has established stable cooperation relationships with many regular clients on a global scale.