Alagille Syndrome (ALGS) is a multisystem autosomal dominant disorder with a wide variety of clinical manifestations. It is also known as arteriohepatic dysplasia, Alagille-Watson syndrome, Watson-Miller syndrome or syndromic bile duct paucity. The clinical manifestations are variable, even within the same family, and commonly include hepatic (cholestasis, characterized by bile duct paucity on liver biopsy), cardiac (primarily involving the pulmonary arteries), renal skeletal (butterfly vertebrae), ophthalmologic (posterior embryotoxon), and facial abnormalities.
As per NORD, ALGS is a rare genetic disorder that can affect multiple organ systems of the body including the liver, heart, skeleton, eyes and kidneys.
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The Alagille Syndrome market report also covers emerging drugs, current treatment practices, Alagille Syndrome market share of the individual therapies, current and forecasted Alagille Syndrome Market Size from 2017 to 2030 segmented by seven major markets.
The report provides a detailed current Alagille Syndrome treatment practice/algorithm, market drivers, market barriers, and unmet medical needs to curate the best of the opportunities and assesses the underlying potential of the market.
Alagille Syndrome Market Key Facts
It has been observed that Alagille Syndrome affects males and females in equal numbers.
As per the National Institute of Health (NIH), the estimated prevalence of Alagille syndrome is 1 in 70,000 newborns. This figure is based on diagnoses of liver disease in infants and may be an underestimation because some people with Alagille syndrome do not develop liver disease during infancy.
As per National Organization for Rare Disorders (NORD), Alagille syndrome affects males and females in equal numbers. The incidence of Alagille syndrome has been estimated to be approximately 1 in 30,000-45,000 individuals in the general population.
As per the Delveinsight, among the 7MM, the US accounts for approximately half of the Alagille Syndrome market share among the overall market size in 2017.
Key Benefits of Alagille Syndrome Market Report
Alagille Syndrome market report provides an in-depth analysis of Alagille Syndrome Market Size, Share, Trend, Epidemiology and Market Forecast till 2030, in 7 major markets i.e. EU5 (Germany, Italy, Spain, France, and the UK), Japan, and the United States.
The Alagille Syndrome market report will help in developing business strategies by understanding the Alagille Syndrome Market trends & developments, key players, and future market competition that will shape and drive the Alagille Syndrome market in the upcoming years.
The Alagille Syndrome market report covers Alagille Syndrome’s current treatment practices, emerging drugs, market share of the individual therapies in 7MM.
The report provides a detailed assessment of the Alagille Syndrome market in terms of market drivers & barriers, Unmet Needs, market opportunities, patient population, comparative analysis of pipeline products with detailed clinical profiles, and other factors.
Alagille Syndrome Market
Alagille Syndrome market size is expected to increase during the study period owing to the increasing incident/prevalent population of ALGS patients in the 7MM
The Alagille Syndrome market outlook section of the report helps to build a detailed comprehension of the historic, current, and forecasted Alagille Syndrome market trends by analyzing the impact of current therapies on the market, unmet needs, drivers, and barriers, and demand for better technology.
The report gives a thorough detail of the Alagille Syndrome market trend of each marketed drug and late-stage pipeline therapy by evaluating their impact based on the annual cost of therapy, inclusion and exclusion criteria, mechanism of action, increasing patient pool, covered patient segment, expected launch year, competition with other therapies, and view of the key opinion leaders.
Alagille Syndrome Epidemiology
The Alagille Syndrome epidemiology section covers insights about the historical and current Alagille Syndrome patient pool and forecasted trends for every seven major countries (i.e. the United States, EU5 countries (Germany, Spain, Italy, France, and the United Kingdom), and Japan from 2017 to 2030.
It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. The epidemiology section also provides the diagnosed patient pool and their trends along with assumptions undertaken.
Alagille Syndrome Drugs Uptake and Key Market Players
The Alagille Syndrome Drugs Uptake section focuses on the rate of uptake of the potential drugs recently launched in the Alagille Syndrome market or expected to get launched in the market during the study period. The analysis covers Alagille Syndrome market uptake by drugs; patient uptake by therapies; and sales of each drug.
Report’s Drugs Uptake section helps in understanding the drugs with the most rapid uptake, reasons behind the maximal use of new drugs and allow the comparison of the drugs on the basis of market share and size which again will be useful in investigating factors important in market uptake and in making financial and regulatory decisions.
The available therapeutics treatment options in the Alagille Syndrome landscape aim to reduce complications arising due to genetic mutation. The dynamics of the Alagille Syndrome (ALGS) market is anticipated to change in the coming years owing to the improvement in the rise in the number of healthcare spending across the world.
Alagille Syndrome companies:
And many others.
Alagille Syndrome therapies covered in the report include:
And many more.
The Alagille Syndrome (ALGS) pipeline portraits a high medical unmet need for a better treatment pattern in the market in upcoming years.
Table of Content
1. Key Insights
2. Executive Summary
3. Alagille Syndrome Competitive Intelligence Analysis
4. Alagille Syndrome Market Overview at a Glance
5. Alagille Syndrome Disease Background and Overview
6. Alagille Syndrome Patient Journey
7. Alagille Syndrome Epidemiology and Patient Population
8. Alagille Syndrome Treatment Algorithm, Current Treatment, and Medical Practices
9. Alagille Syndrome Unmet Needs
10. Key Endpoints of Alagille Syndrome Treatment
11. Alagille Syndrome Marketed Products
12. Alagille Syndrome Emerging Therapies
13. Alagille Syndrome Seven Major Market Analysis
14. Attribute Analysis
15. Alagille Syndrome Market Outlook (7 major markets)
16. Alagille Syndrome Access and Reimbursement Overview
17. KOL Views on the Alagille Syndrome Market.
18. Alagille Syndrome Market Drivers
19. Alagille Syndrome Market Barriers
21. DelveInsight Capabilities
Alagille syndrome Epidemiology Forecast
DelveInsight’s Alagille syndrome – Market Insights, Epidemiology and Market Forecast – 2030 report provides an in-depth understanding of historical and forecasted epidemiology in the 7MM.
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