New York, USA – March 23, 2021 – At present, bispecific antibody (bsAb) drugs have been proven to have broad therapeutic potential and market prospects. The malleability and versatility of this kind of antibody attract an increasing number of researchers to develop such molecules as therapeutic agents. Although the potential to introduce new functions by engineering two different antigen binding sites was realized decades ago, bsAb development is still complicated and challenging.
Recognized as the leading custom service provider with extensive experience in various antibody production and engineering fields, Creative Biolabs has updated the portfolio of bsAb analysis services to perform comprehensive analysis for clients’ bsAb projects to ensure quality and function.
• BsAb Biochemistry Characterization
Biochemical characterization is an indispensable process in the development of bsAbs, and with an established comprehensive platform, the expert team at Creative Biolabs is confident in providing bsAb purity measurement, molecular weight/mass measurement, and molecular structure analysis.
• BsAb Stability Analysis
Creative Biolabs has extended its bsAb stability analysis services to cover thermal stability measurement, aggregation measurement, and in vitro serum stability measurement. The techniques used for different analytical approaches can be fully customized according to different projects. For example, Dynamic Light Scattering (DLS), Sedimentation Velocity Analytical Ultracentrifugation (SV-AUC), Electrospray Differential Mobility Analysis (ES-DMA), and Field Flow Fractionation (FFF), etc., are all available for aggregation measurement.
• BsAb Functional Analysis
Taking advantage of the state-of-the-art instruments, Creative Biolabs can assist every client to solve BsAb functional analysis problems with a plethora of functional analysis services, including affinity measurement, antibody-dependent cell-mediated cytotoxicity (ADCC) assay, complement dependent cytotoxicity (CDC) assay, and antibody-dependent cellular phagocytosis (ADCP) assay, which can measure efficacy and safety of bsAb products or candidates.
• BsAb PK/PD Analysis
Creative Biolabs is also specialized in pharmacokinetic and pharmacodynamic (PK/PD) analysis, of which both model dependent and model independent analysis services are available to evaluate the PK/PD of specific bsAbs. The analysis information can meet the unique needs of worldwide clients with valuable insights into the design of preclinical and clinical studies of bsAbs.
More information about bsAb services can be found at https://www.creative-biolabs.com/bsab.
About Creative Biolabs
Over the past 15 years, Creative Biolabs has grown into a recognized world leader in antibody discovery, engineering, production, and analysis. The bispecific antibody (bsAb) team has a collective of experienced scientists committed to providing high-quality services to customers all over the world, covering bsAb design, purification, bsAb engineering, manufacturing and analysis service. With the cutting-edge platforms and methods, a comprehensive list of bsAb products is also available to customers in academia and industry fields.