New York, USA – March 23, 2021 – Immunotherapy has emerged to attract increased attention because of its low-risk and convenient advantages that allow the targeted therapy to be realized in clinical practice.
HLA typing and KIR typing are essential for immunotherapy research to understand a variety of drug discoveries and working mechanisms of cancer cells. Equipped with a high-quality system and cooperated with outstanding scientists, Creative Biolabs has established professional platforms of gene testing in immunotherapy research that helps explore more possible targeted drugs and develop solutions for cancer.
HLA Typing Works in Collaboration with CAR-T Cells and Its Role in Immunotherapy
Immunotherapy that is heavily dependent on CAR-T cells can enlist and strengthen the power of a patient’s immune system to attack tumors, thereby revolutionizing the treatment of cancer and bringing new hope to patients. Due to its tremendous potential and proven benefits, Creative Biolabs has completed painstaking research on CAR-T cell development, including pre-clinical investigation and clinical phase development.
Types of services of CAR-T therapy offered by Creative Biolabs involve biomarker identification & selection, high affinity ScFv generation, CAR design & construction, virus packaging & CAR gene delivery, CAR-T in vitro assay, and CAR-T preclinical in vivo assay, to guide promising experimental results.
Human leukocyte antigen (HLA) typing is related to CAR-T cells when employing in the adoptive immunotherapy as CAR endows T cells with specificity to T-cells independent of HLA.
To better accomplish these momentous tasks, researchers require the best system to obtain HLA typing data relevant to cancer study. Creative Biolabs has developed a dedicated NGS-based solution and high-quality system to provide accurate and high-resolution HLA typing results to satisfy the needs of customers.
KIR Typing Introduction
One glycoprotein expressed on natural killer (NK) cells, known as killer cell immunoglobulin-like receptors (KIRs), plays a vital role in detecting virus-infected or transformed cells, as well as inhibiting the cytotoxic activity of NK cells in their recognition of MHC molecules. High resolution DNA-based genotyping analysis of KIR polymorphism revealed that KIR is involved in the pathogenesis of some cancers.
To advance these novel therapeutics, specialized experiments are crucial in investigating all KIR genes and obtaining data with 100% accuracy. Creative Biolabs now offers a full range of KIR typing services covering all KIR genes and alleles, with test delivered results on an established High-Throughput Sequencing (HTS) platform.
Today’s rich experimental experience has led to the success of Creative Biolabs in carrying out HIR and KLA genetic tests to optimize a risk-based approach that advances cutting-edge innovations in which consumers can have confidence.
About Creative Biolabs
Creative Biolabs is a fully integrated, specialized biotechnology company focused on developing comprehensive solutions for immunotherapy clinical trials and researches based on proven platforms. It attaches great importance to interaction collaborative interactions, fast delivery of solutions, and providing the highest level of quality services in accordance with customer requirements.