New York, USA – April 1, 2021 – Creative Bioarray, the world’s leading biotechnology company focuses on offering high quality products and services including cell services, biosample services and histology services to accelerate life science research, help scientist solve complex analytical issues. Recently, Creative Bioarray announced the release of its comprehensive CABR chromosome probes in order to improve chromosome studies.
Creative Bioarray provides the most comprehensive list of CABR probes, which can be used for a wide range of applications in related areas, such as detecting gene amplification, deletion, translocation and chromosomal aneuploidy related to tumor and genetic disease spectrum; this enables molecular diagnosis Technology is very important for clinical diagnostics and the pharmaceutical industry.
Currently, Creative Bioarray has a full set of DNA probe libraries for specific chromosomes (whole chromosomes, specific chromosomal arms or chromosome fragments) that are fluorescently labeled. DNA is prepared by chromosome staining, and then the probe is hybridized to mitosis by fluorescence in situ hybridization (chromosome separation). After the hybridization is completed, a multi-color coating effect will be produced at the hybridization site. Then, researchers can observe the fluorescence intensity on the chromosomes under a fluorescence microscope to analyze and study chromosome recombination, aberrations, and homologous genes.
Centromeric probes can be combined with the centromeric regions of specific chromosomes to measure the number and type of specific chromosomes. The centromere probe binds to the repetitive alpha satellite DNA sequence. The repetitive sequence of DNA is different from other DNA, which is tightly wound throughout the cell cycle.
Subtelomere-specific probes have been used to focus on specific subtelomere regions and have been developed in the research of new disease syndromes. Subtelomere-specific probes can also be used for research on autism, recurrent miscarriage and other aspects. CABR satellite enumeration probes specifically identify highly repetitive DNA sequences in 24 human chromosomes. These highly repetitive DNA sequences exist in the centromeres, centromeres and heterochromatin regions of chromosomes.
“Our chromosome probe products are highly specific and sensitive in identifying human pathology, and centromere probes can be used to detect single or aneuploid chromosomes, and can also be used as reference probes for other genes.” said Hannah Cole, the marketing director of Creative Bioarray, she also added, “Our subtelomere-specific probes are selected from the unique sequences at the end to obtain the most possible chromosome specificity, which can be used for routine subtelomere enumeration and integrity testing. We are pleased to provide our customers with high-quality chromosome probes to meet different needs.”
About Creative Bioarray
Founded in 2005, Creative Bioarray is dedicated to offering customers with innovative biotechnology products and services for research use to greatly enhance and drive innovation and standards in science. As a well-recognized industry leader with more than 10 years of experience and in-house experts supported, Creative Bioarray has already countenanced research all around the world.