DelveInsight’s ‘Complex Regional Pain Syndrome (CRPS) Market Insights, Epidemiology and Market Forecast 2030’ report delivers an in-depth understanding of the CRPS, historical and forecasted epidemiology as well as the CRPS market trends in the United States, EU5 (Germany, France, Italy, Spain, and United Kingdom), and Japan.
Complex Regional Pain Syndrome Disease Overview
Complex Regional Pain Syndrome (CRPS) is one of the most challenging chronic pain condition that is characterized by progressively worsening spontaneous regional pain without dermatomal distribution.
The pain experienced is out of proportion in time and severity to the inciting event and accompanied by symptoms that vary in severity including skin changes, autonomic dysfunction, abnormal sensory and motor changes, and trophic changes. CRPS may develop after major trauma, surgery, or minor injury, and progresses with a variable course that ranges from self-limiting, mild symptomatology to chronic disease.
In many cases, disease progression is debilitating and severely limits patients’ quality of life, creating a tremendous burden on patients and their families. Over time, CRPS has been defined and redefined. CRPS develops after an inciting noxious stimulus to an affected limb. There is little agreement with regards to the etiology, symptoms, clinical presentation, diagnosis, or treatment of CRPS.
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Complex Regional Pain Syndrome Disease Diagnosis
There are no objective diagnostic tests for CRPS. Since, its pathophysiologic basis of CRPS is not fully understood, mechanism-based diagnosis is not yet feasible. Therefore, the diagnosis of CRPS is based solely on clinical signs and symptoms. The actual diagnosis of CRPS is made solely based on history and physical examination to determine whether a patient meets CRPS diagnostic criteria (often called the Budapest criteria). Other than this, objective testing (thermography, triple-phase bone scan, quantitative sudomotor axon reflex test, or a trial sympathetic ganglion block) may be used to support a clinical diagnosis.
Complex Regional Pain Syndrome Disease Treatment
Current treatment for Complex Regional Pain Syndrome includes:
Non-surgical methods like medications (Pain reliever, Antidepressants and anticonvulsants, Corticosteroids, and Sympathetic nerve-blocking medication)
In the year 2017, the total prevalent case of CRPS was 310,489 in the 7MM which are expected to grow during the study period, i.e., 2017–2030.
Country Wise- CRPS Epidemiology
• In the United States, the total number of prevalent cases of CRPS was 219,317 cases in the year 2017 which are expected to grow during the study period, i.e., 2017–2030.
Complex Regional Pain Syndrome Disease Emerging Drugs
1. TAK-935/OV935 by Ovid Therapeutics/Takeda
2. BHV-5000 by AstraZeneca/Biohaven Pharmaceutical
Complex Regional Pain Syndrome Disease Market Outlook
The Complex Regional Pain Syndrome market size in the 7MM is expected to change during the study period 2017–2030. The therapeutic market of CRPS in the seven major markets was USD 65 million in 2017 which is expected to increase during study period (2017–2030). According to the estimates, the highest market size of CRPS is found in the United States followed by Germany, France, and the UK.
Table of contents
1 Key Insight
2 Executive Summary of Complex Regional Pain Syndrome
3 Complex Regional Pain Syndrome Market Overview at a Glance
4 Disease Background and Overview: Complex Regional Pain Syndrome
5 Case Reports
6 Complex Regional Pain Syndrome Epidemiology and Patient Population
7 United States Epidemiology
8 EU5 Epidemiology
9 Japan Epidemiology
10 Current Complex Regional Pain Syndrome Treatment and Medical Practices
11 Unmet needs
12 Complex Regional Pain Syndrome Marketed Drugs
13 Complex Regional Pain Syndrome Emerging Drugs
14 Complex Regional Pain Syndrome 7MM Market Analysis
15 United States
16 EU-5 countries: Market Outlook
17 Japan Market Outlook
18 Complex Regional Pain Syndrome Market Drivers
19 Complex Regional Pain Syndrome Market Barriers
20 SWOT Analysis
21 Reimbursement and market access
23 DelveInsight Capabilities
25 About DelveInsight
DelveInsight is a leading Business Consultant, and Market Research Firm focused exclusively on life sciences. It supports pharma companies by providing end to end comprehensive solutions to improve their performance.
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