The Acute Kidney Injury market report covers emerging drugs, current treatment practices, market share of the individual therapies, current and forecasted market size from 2019 to 2032. It also evaluates the current treatment practice/algorithm, market drivers & barriers, and unmet medical needs to curate the best of the opportunities and assess the underlying potential of the market.
Acute Kidney Injury: An Overview
Acute Renal Failure, which is now known as Acute Kidney Injury is characterized by azotemia that progresses over several hours or days, with or without oliguria. ARF is commonly defined as an abrupt decline in renal function, clinically manifesting as a reversible acute increase in nitrogen waste products measured by blood urea nitrogen (BUN) and serum creatinine levels over the course of hours to weeks. The disease leads to the abrupt loss of kidney function, leading to the retention of waste products, electrolyte disturbances, and volume status changes.
The risk factors associated with AKI include age, exposure to nephrotoxins, family history, race, ethnicity, gender, and other factors.
Acute Kidney Injury Market Key Facts
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The highest incident cases of Acute Kidney Injury (AKI) were recorded in the United States which was 895,000+ in 2017. While the lowest incident population of Acute Kidney Injury (AKI) was recorded in Japan.
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Among the EU5 countries, Germany had the highest AKI diagnosed discharge cases with 82,900+ cases followed by France while the least number of cases were observed in Spain in 2017.
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AKI is common, especially among the elderly (≥ 65). It has been estimated that it occurs during 2–7% of all hospital admissions and at even higher rates in elderly patients.
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According to Fuhrman et al., under the study titled,”Acute kidney injury epidemiology, risk factors, and outcomes in critically ill patients 16-25 years of age treated in an adult intensive care unit”, stage I AKI occurred with the greatest frequency and stage 3 AKI occurred with the lowest frequency in the 16–25-year old age group.
The market outlook section of the report helps to build a detailed comprehension of the historic, current, and forecasted Acute Kidney Injury market size by analyzing the impact of current and emerging therapies in the market. It also provides a detailed assessment of the market drivers & barriers, unmet needs, and emerging technologies.
The report gives a thorough detail of the Acute Kidney Injury market trend for each marketed drug and late-stage pipeline therapies by evaluating their impact based on the annual cost of therapy, inclusion and exclusion criteria, mechanism of action (MoA), competition with other therapies, brand value, their impact on the market and view of the key opinion leaders.
Acute kidney injury (AKI) Market Drivers –
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Robust Pipeline Activity
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Reimbursement policies
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Increased incidence of hospitalization
Acute Kidney Injury Epidemiology
The epidemiology section covers insights about the historical and current Acute Kidney Injury patient pool and forecasted trends for every seven major countries (7MM) from 2019 to 2032. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. The epidemiology section also provides the diagnosed patient pool and their trends along with assumptions undertaken.
Acute kidney injury (AKI) Epidemiology Segmentation –
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Discharge Diagnosed Cases
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Total Incident Patient Population
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Risk Factor Associated AKI Cases
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Stage-wise Discharged Diagnosed cases
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Renal Transplantation Associated Delayed Graft Function Cases
Acute Kidney Injury Drugs Uptake and Pipeline Development Activities
The drugs uptake section focuses on the rate of uptake of the potential drugs recently launched in the Acute Kidney Injury market or expected to get launched in the market during the study period. The analysis covers Acute Kidney Injury market uptake by drugs; patient uptake by therapies; and sales of each drug.
Report’s Drugs Uptake section helps in understanding the drugs with the most rapid uptake, reasons behind the maximal use of new drugs and allow the comparison of the drugs on the basis of market share and size which again will be useful in investigating factors important in market uptake and in making financial and regulatory decisions.
The report also covers the Acute Kidney Injury Pipeline Development Activities and provides valuable insights about different therapeutic candidates in Phase II, and Phase III stages and the key companies in the market involved in developing targeted therapeutics. It also analyses the recent Development such as collaborations, acquisitions, and mergers, licensing patent details, and other information for emerging therapies.
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Acute Kidney Injury Therapeutics Analysis
Acute kidney injury (AKI) is frequent and is associated with poor outcomes, including increased mortality, a higher risk of chronic kidney disease, and prolonged hospital lengths of stay.
Despite harmonization in clinical definition and staging, identification of novel renal biomarkers for clinical use, and progress in understanding the underlying pathophysiology, there remains a major unmet medical need. The current market persists with various unmet needs related to diagnosis and effective treatment which includes lack of approved therapies for Sepsis AKI, high affordability.
Acute Kidney Injury (AKI) Therapies and Key Companies:
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EA-230: Exponential Biotherapies
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bRESCAP: Alloksys
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ANG-3777 (BB3) : Angion Biomedica
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QPI-1002: Quark Pharmaceuticals
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recAP: AM Pharma
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Reltecimod: AtoxBio
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ASP1128: Astellas Pharma
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Ruconest (Conestat alfa): Pharming Technologies
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MB-102: MediBeacon
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Levosimendan (Simdax): Orion Pharma
And many others
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Table of Content
1. Key Insights
2. Executive Summary
3. Acute Kidney Injury Competitive Intelligence Analysis
4. Acute Kidney Injury Market Overview at a Glance
5. Acute Kidney Injury Disease Background and Overview
6. Acute Kidney Injury Patient Journey
7. Acute Kidney Injury Epidemiology and Patient Population
8. Acute Kidney Injury Treatment Algorithm, Current Treatment, and Medical Practices
9. Acute Kidney Injury Unmet Needs
10. Key Endpoints of Acute Kidney Injury Treatment
11. Acute Kidney Injury Marketed Products
12. Acute Kidney Injury Emerging Therapies
13. Acute Kidney Injury Seven Major Market Analysis
14. Attribute Analysis
15. Acute Kidney Injury Market Outlook (7 major markets)
16. Acute Kidney Injury Access and Reimbursement Overview
17. KOL Views on the Acute Kidney Injury Market.
18. Acute Kidney Injury Market Drivers
19. Acute Kidney Injury Market Barriers
20. Appendix
21. DelveInsight Capabilities
22. Disclaimer
*The table of contents is not exhaustive; the final content may vary.
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