Antithrombin Market size is estimated to reach $811.3 million by 2027, growing at a CAGR of 4.43% during the forecast period 2022-2027. Antithrombins fall under the category of glycoproteins or protease inhibitor which prevent blood clotting compilations (=thrombi) by incapacitating several enzymes responsible for the thickening of the blood. Glycosaminoglycan polysaccharides produced inside the endoplasmic reticulum are examples of anticoagulating substances. Most of the substances that control blood coagulation, platelet, and vascular relaxation are released from a thin membrane called endothelium cells. Antithrombin (AT) binds in vitro and in vivo to endothelial cells through various receptors, including heparan sulfate glycosaminoglycan (HSPG) that could modulate the AT activity. Blood clots are mainly of two types thrombosis and embolism. These blood clumps ascribe to extensive smoking, prolonged sitting, obesity, cancer surgeries. The antithrombin market outlook is quite enchanting as cancer surgeries are expanding. Moreover, sitting for a longer period of time at the office, rising smoking trends among teenagers are factors set to drive the growth of the Antithrombin Market for the period 2022-2027.
Antithrombin Market Segment Analysis-By Form
The Antithrombin Market based on the form type can be further segmented into freeze-dry form and Liquid form. The freeze-dry segment held the largest share in 2021. The growth is owing to several benefits of dry from over liquid. The dry doses are considered to possess higher shelf life as compared to liquid form which makes them the first choice of pharma companies as they are a more cost-effective alternative. There are many drugs that are not as easily soluble as others when it comes to forming a solution that consumes lots of time. Freeze dry forms are less susceptible to bacteria and easier to store. Moreover, the dry form segment is estimated to be the fastest-growing segment with a CAGR of 5.1% over the forecast period 2022-2027. This growth is owing to far-reaching applications ascribing to their effectiveness. According to a study, an antiplatelet drug like aspirin is as cheap as chips. Nevertheless, they diminish the risk of deadly infarction in patients suffering from acute and chronic coronary syndromes by 50-55%.
Antithrombin Market Segment Analysis-By Application
The Antithrombin Market based on application type can be further segmented into Research and development, Therapeutics, and Diagnostics. The therapeutic segment held the largest share in 2021. The growth is owing to proliferating pervasiveness of enzyme deficiencies leading to blood disorders. Therefore, the overall demand for antithrombic drugs has heightened. Moreover, the rising number of surgeries related to accident injuries, cardiovascular diseases like cancer, heart attack are other big factors promoting the growth in the respective segment. Within the US, around 805,000 people suffer heart attacks each year. Moreover, therapeutics is estimated to be the fastest-growing segment with a CAGR of 5.3% over the forecast period 2022-2027. This growth is owing to breakthroughs in the research and development of novel drugs with more effectiveness. Antithrombic drugs and therapies have become an indispensable part of the treatment of acute coronary syndromes such as unstable angina, non-ST segment elevation myocardial infarction.
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Antithrombin Market Segment Analysis-By Geography
The Antithrombin Market based on Geography can be further segmented into North America, Europe, Asia-Pacific, South America, and the Rest of the World. North America held the largest share with 36% of the overall market in 2021. The growth in this segment is owing to the factors such as the ultra-modern and comfortable lifestyles of people residing in North American nations. Consequently, lack of enough physical activity obesity cases is prevailing in the US. On another hand, the widespread of breast cancer in the US are broadening surgical procedures. In 2021, more than 280,000 cases of invasive breast cancer were found in the US. Besides, the prevalence of health complications the presence of world-class health facilities like hospitals and diagnostic laboratories have their fair share in the growth of the respective market. However, the Asia-Pacific segment is expected to be the fastest-growing over the forecast period 2022-2027. This growth is owing to the wide-scale augmentation of cardiovascular diseases as the percentage of old-age people is plunging upward. With growing modernization now people have started adopting contemporary ways or machines to complete their day-to-day work than used to be the case. Therefore, as a result of prolonged sitting many health illnesses such as obesity, dwindling immunity are resulting in serious problems and eventually swelling the usage of antithrombic as a medication.
Antithrombin Market Drivers
Escalating cardiovascular diseases is Anticipated to Boost Product Demand
Many life-threatening complications have come to the foreground in the last two decades but cardiovascular diseases remain the biggest cause behind the demise of millions of people worldwide. Every year cardiovascular disease kills around 17-18 million people throughout the globe. Out of these 17-18 million behind 80-85% of deaths have a common cause that is “heart attack” and the remaining 15-20% are caused by cancer. Therefore, as long as the prevalence of cardiovascular disease is plunging upward the outlook for the antithrombic market is remarkably fascinating.
Prolonged sitting is Expected to Boost Product Demand
Widescale modernization and technological breakthroughs have completely transformed the way human beings used to work in ancient times. Earlier because of little to no presence of machines most of the work used to get completed through hands. But in the 21st we are enjoying the comforts and conveniences that no other generation ever had. People spend more than 10-12 hours sitting throughout the day and out of rest 12-14 hours minimum, 7 hours are devoted to sleeping. Considering this much amount of no-activity obesity cases are increasing which are a major cause of blood clotting. Post COVID-19 lockdowns the percentage of the obese population has escalated. According to a study, 36% of adults in the US were overweight. All these aforementioned factors are stimulating the growth of the antithrombic market.
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Antithrombin Market Challenges
Hampered research and production activities attributed to the COVID-19 are Anticipated to Hamper Market Growth
The world economy has taken a huge hit due to the COVID-19. Most of the production activities were stalled after governments around the globe announced lockdowns in their respective countries. All research projects were put off as all the efforts were diverted toward finding a cure for the virus and mass-producing it. The demand and supply chain encountered major setbacks. As a result of widespread vaccination, the world is getting back on track but amid the omicron scare, the governments are reimposing the restriction which is anticipated to derail the growth of the antithrombic market.
Antithrombin Market Competitive Landscape:
Product launches, mergers and acquisitions, joint ventures, and geographical expansions are key strategies adopted by players in the Antithrombin Market. Key companies of this market are-
Kyowa Hakko Kirin
Thermo Fisher Scientific
March 1, 2021, Barcelona, Spain-based healthcare company “Grifols S.A” successfully acquired 25 plasma centers from bioproducts laboratory “BPL Plasma” in the US. The acquisition was brought to a close with a $370 million payment to the UK-based plasma collector industry. With this move, Grifols now has 344 plasma centers which will provide it an edge over its competitors in plasma supply.
In December 2021, Anti-thrombin III infusion showed improvements in anticoagulation for congenital diaphragmatic hernia patients with extracorporeal membrane oxygenation. The purpose was for achieving effective anticoagulation during neonatal extracorporeal membrane oxygenation (ECMO) without increasing the risk of hemorrhage. AT-III as a continuous infusion in CDH neonates on ECMO provides a decreased need to modify heparin infusion and more consistent therapeutic anticoagulation without increasing the risk of life-threatening bleeding.
Geographically, the North America Antithrombin Market accounted for the highest revenue share in 2021. Asia-pacific is poised to dominate the market over the period 2022-2027.
Broadening medical procedures associated with serious injuries, augmenting obesity complications are said to be preeminent drivers driving the growth of the Antithrombin Market. Crippled supply chains and research activities of antithrombin due to the COVID-19 are said to reduce the market growth.
Detailed analysis on the Strength, Weaknesses, and Opportunities of the prominent players operating in the market will be provided in the Antithrombin Market report.
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