The TRK Fusion Cancer market report covers emerging drugs, current treatment practices, market share of the individual therapies, and current & forecasted market size from 2019 to 2032. It also evaluates the current treatment practice/algorithm, market drivers & barriers, and unmet medical needs to curate the best of the opportunities and assess the underlying potential of the market.
TRK Fusion Cancer: An Overview
The tropomyosin receptor kinase (TRK) family of receptor tyrosine kinases are encoded by NTRK genes and have a role in the development and normal functioning of the nervous system. Since the discovery, as many as 80 different oncogenic NTRK gene fusion have been identified in a wide array of adult and paediatric tumors, providing actionable targets for targeted therapy.
The identification of patients with tumors harboring NTRK fusions followed by the development of highly specific TRK inhibitors has drastically changed the outcomes for this population of patients. While these gene fusions are thought to be rare, they are found in a wide range of histologies and patients of all Organs.
TRK Fusion Cancer Market Key Facts
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Initially identified in colorectal and papillary thyroid carcinomas, NTRK fusions have since been found in multiple tumor types from both adult and pediatric patients. These cancers can be grouped into two general categories according to the frequency at which these fusions are detected. Rare cancer types are highly enriched for NTRK fusions.
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In a study by Gatalica et al. (2019), tissue samples from 11,502 patients were analyzed for 53 gene fusions and sequencing of 592 genes, along with an immunohistochemical evaluation of TrkA/B/C and PD-L1.
As per DelveInsight, the TRK Fusion Cancer Market size is expected to grow in the coming years owing to the increasing incident population of TRK Fusion Cancer patients in the 7MM.
The market outlook section of the report helps to build a detailed comprehension of the historical, current, and forecasted TRK Fusion Cancer market size by analyzing the impact of current and emerging therapies in the market. It also provides a thorough assessment of the market drivers & barriers, unmet needs, and emerging technologies.
The report gives complete detail of the TRK Fusion Cancer market trend for each marketed drug and late-stage pipeline therapies by evaluating their impact based on the annual cost of therapy, mechanism of action (MoA), competition with other therapies, brand value, and their impact on the market.
TRK Fusion Cancer Epidemiology
The epidemiology section provides insights into the historical, current, and forecasted epidemiology trends in the seven major countries (7MM) from 2019 to 2032. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. The epidemiology section also provides a detailed analysis of diagnosed patient pool and future trends.
TRK Fusion Cancer Epidemiology Segmentation
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Total Incident cases of TRK Fusion Cancer
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Treated cases of TRK Fusion Cancer
TRK Fusion Cancer Drugs Uptake and Pipeline Development Activities
The drugs uptake section focuses on the rate of uptake of the potential drugs recently launched in the TRK Fusion Cancer market or expected to get launched during the study period. The analysis covers TRK Fusion Cancer market uptake by drugs, patient uptake by therapies, and sales of each drug.
Moreover, the therapeutics assessment section helps understand the drugs with the most rapid uptake and the reasons behind the maximal use of the drugs. Additionally, it compares the drugs based on market share.
The report also covers the TRK Fusion Cancer Pipeline Development Activities. It provides valuable insights about different therapeutic candidates in various stages and the key companies involved in developing targeted therapeutics. It also analyses recent developments such as collaborations, acquisitions, mergers, licensing patent details, and other information for emerging therapies.
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TRK Fusion Cancer Therapeutics Analysis
Research is underway to identify treatment approaches that may address some of the challenges to existing treatment challenges in the TRK Fusion Cancer segment. Several pharma and biotech companies are actively working in TRK Fusion Cancer Market to improve the treatment scenario.
Some of the key companies in the TRK Fusion Cancer Market include:
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Bayer
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Plexxikon
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Turning Point Therapeutics
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VM Oncology
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CMG Pharmaceuticals
And many others
TRK Fusion Cancer Therapies covered in the report include:
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Selitrectinib
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Repotrectinib
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VMD 928
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PLX 7486
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NOV1601
And many more
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Table of Content (TOC)
1. Key Insights
2. Executive Summary
3. TRK Fusion Cancer Competitive Intelligence Analysis
4. TRK Fusion Cancer Market Overview at a Glance
5. TRK Fusion Cancer Disease Background and Overview
6. TRK Fusion Cancer Patient Journey
7. TRK Fusion Cancer Epidemiology and Patient Population
8. TRK Fusion Cancer Treatment Algorithm, Current Treatment, and Medical Practices
9. TRK Fusion Cancer Unmet Needs
10. Key Endpoints of TRK Fusion Cancer Treatment
11. TRK Fusion Cancer Marketed Products
12. TRK Fusion Cancer Emerging Therapies
13. TRK Fusion Cancer Seven Major Market Analysis
14. Attribute Analysis
15. TRK Fusion Cancer Market Outlook (7 major markets)
16. TRK Fusion Cancer Access and Reimbursement Overview
17. KOL Views on the TRK Fusion Cancer Market.
18. TRK Fusion Cancer Market Drivers
19. TRK Fusion Cancer Market Barriers
20. Appendix
21. DelveInsight Capabilities
22. Disclaimer
*The Table of Contents (TOC) is not exhaustive; the final content may vary. Refer to the sample report for the complete table of contents.
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About DelveInsight
DelveInsight is a leading Business Consultant and Market Research Firm focused exclusively on life sciences. It supports pharma companies by providing end-to-end comprehensive solutions to improve their performance.
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