New York, October 25th, 2018- Creative Biolabs, an industry leader in discovery and optimization of antibodies, recently announced the launching of the new Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) antibody featuring advanced antibody research tools, professional and technical support and fast global delivery.
Creative Biolabs is committed to offering the high-quality and optimal GAPDH antibodies and antibody products for your research needs at the lowest cost level in the industry.
Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) is characterized with a well-known housekeeping gene with the glycolysis feature. Identifying the diverse functions of GAPDH depends on the use of GAPDH Antibodies, which can identify interacting proteins or examine the protein’s subcellular localization because GAPDH is highly expressed in most cells and is essential in the glycolytic pathway. Therefore, GAPDH antibodies play a vital role in investigating basic cellular mechanisms and understanding the diverse functions of GAPDH. Moreover, GAPDH antibodies also can be widely used to monitor the content of the constitutive reference protein.
GAPDH antibodies are important for glycolysis and nuclear functions, because they get involved in both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, and nuclear activities including transcription, RNA transport, DNA replication, and apoptosis. Their nuclear functions are probably distributed to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2, and PRKDC (by similarity). Besides, Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate.
GAPDH antibodies have a wide application in different areas. Since GADPH is highly expressed in most cell types, GAPDH mRNA levels are often used as standards in mRNA expression studies. GAPDH is also a popular loading control for Western blot assays. Other applications for the GAPDH antibody include RT-PCR (reverse transcription polymerase chain reaction) studies, immunoprecipitation, immunofluorescence and immunohistochemistry. GAPDH antibody studies have shown the protein involved in a number of other processes, including DNA replication and repair, and initiation of transcription. It has been reported that the protein binds to a number of other proteins, including actin and tubulin, and may play a role in the regulation of apoptosis, as GADPH migration to the nucleus has been reported in apoptotic cells. The protein is also implicated in several pathological diseases, including Alzheimer’s, neurodegenerative and metabolism diseases and cancers.
Creative Biolabs’ scientists are focusing on discovering and developing high-quality antibody products for global academic and biotechnology companies, through its excellent science and technology, advanced antibody research tools and professional technical support. Creative Biolabs aims at providing customized antibody final products from any species, so as to satisfy the customers’ needs for multiple applications and research areas.
About Creative Biolabs
As a pioneer and the undisputed global leader in antibody discovery and manufacturing, Creative Biolabs is programming native monoclonal and polyclonal antibodies for both academic and industrial use. Our advanced antibody production platforms and highly professional scientists allow us to provide superior GAPDH antibody services.
Company Name: Creative Biolabs
Contact Person: Bella Smith
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Address:45-1 Ramsey Road
State: New York
Country: United States