New York, March 26 Creative Biolabs, a leading pre-clinical vaccine development and production company, now offers safe and efficacious nucleic acid vaccines, that is, DNA and RNA vaccine.
As a professional, Creative Biolabs has effectively supported the vaccine industry for decades with a full range of vaccine design and production services and related products. We combine the traditional and the most updated genetic engineering technologies to efficiently produce highly immunogenic vaccines addressing urgent unmet medical needs.
A vaccine is a biological agent that provides active acquired immunity to a particular disease and usually contains an agent that resembles a disease-causing microorganism. In contrast to recombinant bacteria or virus vaccines, nucleic acid vaccines consist only of DNA or RNA, which is uptake by cells and transformed into protein, protecting against disease by injection with genetically engineered DNA (as a plasmid) or RNA (as mRNA). Their immunogenicity and efficacy have been analyzed in a large number of systems, and the results of preclinical studies have supported human clinical trials. Most importantly, genetic vaccines are relatively inexpensive and easy to manufacture and use.
However, naked nucleic acid is relatively inefficient, particularly in larger animals and the DNA of the vaccine may be integrated into the host chromosome, resulting in oncogenes or turn off tumor suppressor genes, which indicates that more efforts are required to enhance the efficacy of RNA and DNA vaccine. Through years of accumulation, scientists in Creative Biolabs have concluded the following rules to develop efficacious nucleic acid vaccines:
• Antigens can be modified to make them better immunogens
• Exogenous cytokines can enhance or direct the immune response
• DNA-encoded co-stimulatory molecules can enhance APC-functions
• Bacterial DNA-sequences called immune stimulatory sequences can be potent adjuvants
Well development of a vaccine project requires an experienced partner who understands the unique complexity presented by this important research area. a full range of custom vaccine development services from design to validation to downstream GMP manufacturing. Specialized in vaccine field for decades, Creative Biolabs are confident to assist clients exploiting a wide array of novel technologies to produce high-quality vaccines. More details can be reached at https://www.creative-biolabs.com/vaccine.
About Creative Biolabs
Creative Biolabs, headquartered in New York, is a leading custom service provider in the field of vaccine development, preclinical assessment and GMP manufacturing. The technical and regulatory experts can provide vaccine developers with a full range of products and vaccine related services. Traditional and the most updated genetic engineering technologies are combined to efficiently produce highly immunogenic and safe vaccines to address emergency unmet medical needs. The service portfolio includes a full range of vaccine design for client’s specific requirements that covers vaccine target validation, vaccines targeting bacterial, viral, fungal, parasites, cancer markers and more. Formulation optimization services are also available for maximum potency, including improving delivery systems, a great variety of adjuvant products and services like PRR Ligands scanning and adjuvants synthesis.
Company Name: Creative Biolabs
Contact Person: Candy Swift
Email: Send Email
Address:45-1 Ramsey Road
State: New York
Country: United States