On May 25, 2019, Alfa Chemistry announced to offer a wide range of heterocyclic organic compounds to support academic research and industrial manufacturing. The heterocyclic organic compounds provided by Alfa Chemistry include furans, imidazoles, indoles, pyrazines, pyridines, pyrimidines, quinolines, thiophenes and so on.
What is heterocyclic organic compound?
A heterocyclic organic compound is a cyclic organic compound having atoms of at least two different elements as members of its ring. Heterocyclic compounds are extensively distributed in nature and play a vital role in the metabolism of all living cells. And heterocyclic chemistry is a branch of organic chemistry, and it involves the synthesis, properties and applications of these heterocycles. Heterocyclic compounds dominate the heterocyclic chemistry due to their constructive properties as therapeutic agents, drugs, dyes and the like.
Applications of heterocyclic organic compounds
Nitrogen-containing heterocycles have been used as pharmaceutical compounds for centuries. Nitrogen-containing heterocycles are present in a variety of natural products and are of great importance in a variety of pharmaceutical applications. Heterocyclic compounds are useful as anticancer agents, antituberculosis drugs, analgesics, hypnotics, antimalarials, antibacterial agents and insecticides. Drugs containing an aromatic five-membered nitrogen heterocyclic compound include cholesterol-lowering Atorvastatin, anti-inflammatory Celecoxib, anti-ulcer Cimetidine, antifungal Fluconazole, and antihypertensive Losartan. Imidazole is part of the theophylline molecule in tea and coffee beans that stimulates the central nervous system. Imidazole can be incorporated into many important biomolecules and it has become an important part of many drugs.
Heterocyclic compounds are very important in organic chemistry, and they account for more than half of known organic compounds. Heterocyclic compounds have great diversity in chemical and physical properties, and that’s why the heterocycles can be widely used in the fields of pharmacy, agrochemistry, electronics, and the like. Caffeine is a prime example of everyday chemicals composed of heterocycles. The main class of heterocycles are heterocycles containing oxygen, nitrogen or sulfur. Part of the reason they are so common may be because they are capable of performing a wide range of reactions under different conditions. For example, in the Knoevenagel condensation, pyridine can be used as a polar low-reactivity solvent, and in the esterification and acylation reactions, pyridine can be used as an activator of a carboxylic acid halide or anhydride.
Several heterocyclic compounds involved in biology include nucleic acids (nitrogen-containing purine and pyrimidine bases in DNA), vitamins (thiamine B1, riboflavin B2, nicotinamide B3), essential amino acids (proline, histidine and tryptophan) and heme (haemoglobin). Heterocyclic compounds can be classified into aliphatic and aromatic compounds. Aliphatic heterocycles are cyclic analogs of amines, ethers, thioethers, amides and the like. Aromatic heterocyclic compounds are those which have a heteroatom in the ring and acting in a manner similar to benzene in some properties. They are also the main components of some biomolecules, such as DNA, RNA, chlorophyll, hemoglobin, vitamins etc.. Many biomolecules in the human body contain heterocycles, from the neurotransmitter serotonin to enzymes that help break down and metabolize food.
“Heterocyclic organic compounds play a very important role in most drugs, most biomass, and many natural and synthetic dyes. To support academic research and industrial manufacturing, we have decided to provide Heterocyclic organic compounds to meet the needs of our global customers,” said Dr. Brenda Randy, the marketing manager of Alfa Chemistry.
About Alfa Chemistry
Alfa Chemistry offers an extensive catalog of building blocks, reagents, catalysts, reference materials, and research chemicals in a wide range of applications. It also provides analytical services and laboratory services to the customers. Products listed on the website are either in stock or can be resynthesized within a reasonable time frame. In stock products can be shipped out within 3-5 business days upon receipt of customers’ purchase order.
More than 300 different organizations from at least 40 countries worldwide have used Alfa Chemistry’s products and services since its inception. A large part of Alfa Chemistry’s customers are pharmaceutical and biotechnology companies, including Pfizer, Novartis, Merck & Co., Johnson & Johnson, AstraZeneca, and Bayer. Alfa Chemistry is also a preferred partner for many universities and non-profit institutes.
Company Name: Alfa Chemistry
Contact Person: Tylor Keller
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Address:2200 Smithtown Avenue, Room 1 Ronkonkoma
State: New York 11779-7329
Country: United States