(Companies: Emulate, TissUse, Mimetas, Hµrel And Nortis)
Organs-on-chips (OOCs) of the organ-on-chip market are small plastic devices with biocompatible microfluidic chambers, which contain multiple live human cells in a 3D culture that simulate key physiological functions of body organs. These cells are placed in an environment which artificially replicates aspects of human body such as morphology, movement, flow, electrical stimuli and liquid gradients. The resulting device mimics human organ functions and is used to study biomedical phenomena.
Scientific advances in cell biology, microfabrication and microfluidics have led to the development of OOCs. They are tiny chip-like structures with specific embedded cells. The combination of chip and cells in the presence of suitable conditions mimic the key functions of an organ in miniature formats outside the body.
The global organ-on-chips market reached a value of nearly $34 million in 2017, having grown at a compound annual growth rate (CAGR) of more than 55% since 2013.
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Organ-On-Chip Market Size
The global organ-on-chip market size is expected to grow at an annual growth rate of around 70% by 2021. The market is expected to rise at this high annual growth rate due to an increase in the number of collaborative sales agreements between the pharmaceutical companies and university spin-offs and the entry of new advanced models of OOCs into the market. The market will be held back by lack of regulatory approval for using OOC test results for drug approvals, together with the complications in manufacturing the devices which will deter new entrants and inhibit mass production.
The key players include Emulate, CN-Bio Innovations, InSphero, Mimetas, TissUse, Hµrel and Nortis.
HemoShear was the largest competitor in the organ-on-chip market in 2017, with nearly $5 billion share of the market. HemoShear is a biotechnology company focused on discovering novel biological targets and developing drugs to treat children’s rare metabolic disorders. Their goal is to discover drugs that save the lives of children who are born with metabolic defects and are unable to sustain basic biochemical processes necessary for life. The company is headquartered in Virginia, USA.
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Few Points from Table of Content:
- 1. Executive Summary
- 2. Preface
- 3. Global Organ-On-Chip Market – Introduction
- 4. Organ-On-Chip Market Characteristics
- 4.1.1 Organs-On-Chips Origin And Significance
- 4.1.2 Organ-On-Chip Features
- 4.2 Organ-On-Chip Market – Product Analysis
- 4.2.1 Technical Description
- 4.2.2 Typical Organ-On-Chip Structure
- 4.2.3 Product Design Materials
- 4.2.4 Product Design Methodologies
- 5. Overview Of Organ-Specific Models
- 5.1 Lung-On-Chip
- 5.2 Heart-On-Chip
- 5.3 Liver-On-Chip
- 5.4 Intestine-On-Chip
- 5.5 Kidney-On-Chip
- 5.6 Skin-On-Chip
- 5.7 Blood-Brain-Barrier-On-Chip
- 5.8 Human-On-Chip
- 6. Organ-On-Chip Applications
- 7. Organ-On-Chip Commercialization
- 8. Organ-On-Chip Market Penetration
- 9. Price Information
- 10. Organ-On-Chip Market Trends and Models
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