New York, USA – Based on the well-established bispecific antibody (BsAb) develop platforms, Creative biolabs offers two categories of customized BsAb design services, that is, Target Based BsAb Design Service and MOA Based BsAb Design Service.
Owing to its unique dual specificity, bispecific antibodies turn out to be increasingly important and widely applied in the field of oncology, immunology, hematology, ophthalmology, osteology, pulmonary and respiratory diseases, pretargeting systems, diagnostics, and gene therapy. Scientists at Creative Biolabs are skillful at bispecific antibody design according to target or mechanism of action (MOA).
1. Target Based BsAb Design Service
Bispecific antibodies have the ability of dual targeting of different disease mediators. Therefore, Creative Biolabs can help customers design the expected BsAbs, including BsAbs targeting different epitopes, ligands, receptors and immune cells.
A full list of different targets are available at Creative Biolabs: ligand targets including but not limited to growth factors, angiogenesis or vasculogenesis factors, and proinflammatory mediators; receptors including cell surface receptors, cytoplasmic receptors, and nuclear receptors; immune cells including T cells, NK cells, other FcR-mediated effector cells.
2. MOA Based BsAb Design Service
Benefiting from the upgraded antibody engineering technologies such as genetic engineering, chemical conjugation, and hybrid-hybridoma, the development of therapeutics BsAbs has taken a giant step forward based on four MOAs, including immune cell recruitment, signaling interference, forced protein associations, and payload delivery, which are all provided at Creative Biolabs.
In the immune cell recruitment, scientists can utilize T cells and Natural killer (NK) cells for tumor prevention/ treatment. BsAbs based on receptor signaling interference that reduce the possibility of escaping mechanisms and increase drug efficacy are provided to block ligand-receptor interactions to control cancer progression. Forced Protein Associations is another MOA of BsAbs available at Creative Biolabs. And BsAb-mediated payload delivery is designed to be widely used in radio-immunodetection and radio-immunotherapy, characterized by higher specificity and sensitivity of imaging and therapeutic effects in cancer treatment.
“In these years, the bispecific antibody field has been revolutionized by the continuous technology advancement. Our top research team has insisted on analyzing the market needs and upgraded our service system. Now we are confident to provide time- and budget-saving BsAb services for global clients,” said by a scientist at Creative Biolabs.
More information on bispecific antibody services and products can be found at https://www.creative-biolabs.com/bsab.
About the Company
Creative Biolabs was established in 2004 by scientists who are dedicated to conquering of cancer. Over the past 10 years, Creative Biolabs has grown into a recognized world leader in antibody (rAb) discovery, engineering, production, and analysis. Standing on the shoulder of a giant, the bispecific antibody (BsAb) team has a collective of experienced scientists committed to providing high-quality services to customers all over the world. Now, with the cutting-edge platforms and methods (quadroma development, chemical conjugation, and genetic engineering), a comprehensive list of bispecific antibody products is available to customers in academia and industry fields.