Bronchiectasis Clinical Pipeline Demonstrates Strong Growth Backed by 15+ Active Industry Players | DelveInsight

DelveInsight’s, “Bronchiectasis Pipeline Insight 2026” report provides comprehensive insights about 15+ companies and 15+ pipeline drugs in Bronchiectasis pipeline landscape. It covers the Bronchiectasis pipeline drug profiles, including Bronchiectasis clinical trials and nonclinical stage products. It also covers the Bronchiectasis pipeline therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

Discover the latest drugs and treatment options in the Bronchiectasis Pipeline @ https://www.delveinsight.com/sample-request/bronchiectasis-pipeline-insight

Key Takeaways from Bronchiectasis Pipeline Report

  • On May 13, 2026- Boehringer Ingelheim initiated a phase III study is to find out whether a medicine called BI 1291583 helps people with bronchiectasis. Participants are put into 2 groups randomly, which means by chance. One group takes BI 1291583 tablets and the other group takes placebo tablets. A placebo tablet looks like the BI 1291583 tablet but does not contain any medicine. Participants take 1 tablet once a day for up to 1 year and 6 months.
  • On May 13, 2026- Sanofi conducted a phase2a study to measure the reduction in mucus plug score at 24 weeks of treatment with SAR445399 compared with placebo in adult participants aged 18 to 80 years with non-cystic fibrosis bronchiectasis (NCFB).
  • On May 13, 2026- Verona Pharma Inc. announced a phase II study is a randomized, double-blind, placebo-controlled study designed to assess the efficacy and safety of ensifentrine inhalation suspension (3 mg) delivered twice daily via standard jet nebulizer over at least 24 weeks, compared to placebo, in subjects with non-cystic fibrosis bronchiectasis (NCFBE).
  • DelveInsight’s Bronchiectasis Pipeline report depicts a robust space with 15+ active players working to develop 15+ pipeline therapies for Bronchiectasis treatment.
  • The leading Bronchiectasis Companies such as AstraZeneca, Insmed Incorporated, SolAeroMed, Boehringer Ingelheim, CSL Behring, Thirty Respiratory Limited, RedHill Biopharma Limited, Chiesi Farmaceutici S.p.A., Armata Pharmaceuticals, Alaxia, Parion Sciences, Santhera Pharmaceuticals, Zambon S.p.A. and others.
  • Promising Bronchiectasis Pipeline Therapies such as Clofazimine Inhalation Suspensio, Ambroxol hydrochloride 30 mg, N-acetylcysteine (NAC) 600 mg, AG1321001 (drug), EZ-2053, GDC-6988, RSS0343 Tabella and others.

Get insights into clinical trials, emerging therapies, and leading companies with DelveInsight @ Bronchiectasis Treatment Drugs

The Bronchiectasis Pipeline Report provides disease overview, pipeline scenario and therapeutic assessment of the key pipeline therapies in this domain. The Bronchiectasis Pipeline Report also highlights the unmet needs with respect to the Bronchiectasis.

Bronchiectasis Overview

Bronchiectasis is an irreversible widening (dilation) of portions of the breathing tubes or airways (bronchi) resulting from damage to the airway wall. The most common cause is severe or repeated respiratory infections, often in people who have an underlying problem with their lungs or immune system.Most people develop a chronic cough, and some also cough up blood and have chest pain and recurrent episodes of pneumonia. Chest x-rays, computed tomography, and breathing tests are usually done to determine the extent and severity of the disorder.

Bronchiectasis Emerging Drugs Profile

  • Benralizumab: AstraZeneca

Benralizumab is a monoclonal antibody used to treat eosinophilic asthma. Benralizumab is a humanized recombinant monoclonal antibody of the isotype IgG1k immunoglobulin that specifically binds to the alpha chain of the interleukin 5 receptor (IL-5R) expressed on eosinophils and basophils. Currently, being evaluated in Phase III stage of clinical trial evaluation to treat Non-cystic Fibrosis Bronchiectasis.

  • S1226: SolAeroMed

S1226 formulation consists of aerosolized carbon dioxide (CO2) and nebulized perflubron; which is delivered into the lung. The delivery of this formulation results in an immediate relaxant effect on the patient’s constricted airways, supported by a lowering of surface tension in inflamed areas (resulting in enhanced bronchial dilation) and possible clearing of mucus plugs of blocked airways.The rescue treatment works on both physiological and biophysical principles offering a unique approach to relieving airway obstruction. CO2 is a potent, but short acting bronchial smooth muscle relaxant. Perflubron is a non-toxic (biocompatible) medical perfluorocarbon with mucolytic and surfactant properties that acts synergistically with CO2 to provide a much greater and more prolonged broncho-dilatory effect. The drug product is hypothesized to open constricted airways through at least three distinct mechanisms. Firstly, through the relaxant effect of CO2 (alone and dissolved into perflubron) on constricted airway smooth muscle; secondly, by lowering surface tension in the inflamed airways; and finally by possibly facilitating penetration and lubrication of mucus plugs, thus enhancing mucociliary clearance. Furthermore it works by an entirely different mechanism to the ß-adrenergic agonists and thus complements, rather than replaces, existing treatments.

  • Brensocatib: Insmed

Brensocatib is a small molecule, oral, reversible inhibitor of dipeptidyl peptidase I (DPP1) being developed by Insmed for the treatment of patients with bronchiectasis. DPP1 is an enzyme responsible for activating neutrophil serine proteases (NSPs), such as neutrophil elastase, in neutrophils when they are formed in the bone marrow. Neutrophils are the most common type of white blood cell and play an essential role in pathogen destruction and inflammatory mediation. In chronic inflammatory lung diseases, neutrophils accumulate in the airways and result in excessive active NSPs that cause lung destruction and inflammation. Brensocatib may decrease the damaging effects of inflammatory diseases such as bronchiectasis by inhibiting DPP1 and its activation of NSPs.

Explore groundbreaking therapies and clinical trials in the Bronchiectasis Pipeline @ New Bronchiectasis Drugs

The Bronchiectasis Pipeline Report Provides Insights into

  • The report provides detailed insights about companies that are developing therapies for the treatment of Bronchiectasis with aggregate therapies developed by each company for the same.
  • It accesses the Different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for Bronchiectasis Treatment.
  • Bronchiectasis Companies are involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.
  • Bronchiectasis Drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type.
  • Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement and financing details for future advancement of the Bronchiectasis market

Pulmonary Fibrosis Companies

AstraZeneca, Insmed Incorporated, SolAeroMed, Boehringer Ingelheim, CSL Behring, Thirty Respiratory Limited, RedHill Biopharma Limited, Chiesi Farmaceutici S.p.A., Armata Pharmaceuticals, Alaxia, Parion Sciences, Santhera Pharmaceuticals, Zambon S.p.A. and others.

Bronchiectasis pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as

  • Inhalation
  • Inhalation/Intravenous/Oral
  • Intranasal
  • Intravenous
  • Intravenous/ Subcutaneous
  • NA
  • Oral
  • Oral/intranasal/subcutaneous
  • Parenteral
  • Subcutaneous

Bronchiectasis Products have been categorized under various Molecule types such as

  • Antibody
  • Antisense oligonucleotides
  • Immunotherapy
  • Monoclonal antibody
  • Peptides
  • Protein
  • Recombinant protein
  • Small molecule
  • Stem Cell
  • Vaccine

Learn about new drugs, pipeline developments, and key companies with DelveInsight’s expert analysis @ Bronchiectasis Market Drivers and Barriers

Scope of the Bronchiectasis Pipeline Report

  • Coverage- Global
  • Bronchiectasis Companies- AstraZeneca, Insmed Incorporated, SolAeroMed, Boehringer Ingelheim, CSL Behring, Thirty Respiratory Limited, RedHill Biopharma Limited, Chiesi Farmaceutici S.p.A., Armata Pharmaceuticals, Alaxia, Parion Sciences, Santhera Pharmaceuticals, Zambon S.p.A. and others.
  • Bronchiectasis Pipeline Therapies- Clofazimine Inhalation Suspensio, Ambroxol hydrochloride 30 mg, N-acetylcysteine (NAC) 600 mg, AG1321001 (drug), EZ-2053, GDC-6988, RSS0343 Tabella and others.
  • Bronchiectasis Therapeutic Assessment by Product Type: Mono, Combination, Mono/Combination
  • Bronchiectasis Therapeutic Assessment by Clinical Stages: Discovery, Pre-clinical, Phase I, Phase II, Phase III

Get the latest on Bronchiectasis Therapies and clinical trials. Download DelveInsight’s in-depth pipeline report today! @ Bronchiectasis Companies, Key Products and Unmet Needs

Table of Content

  1. Introduction
  2. Executive Summary
  3. Bronchiectasis: Overview
  4. Pipeline Therapeutics
  5. Therapeutic Assessment
  6. Bronchiectasis – DelveInsight’s Analytical Perspective
  7. Late Stage Products (Phase III)
  8. Benralizumab: AstraZeneca
  9. Drug profiles in the detailed report…..
  10. Mid Stage Products (Phase II)
  11. S1226: SolAeroMed
  12. Drug profiles in the detailed report…..
  13. Early Stage Products (Phase I)
  14. CSL787: CSL Behring
  15. Drug profiles in the detailed report…..
  16. Preclinical and Discovery Stage Products
  17. AP-PA02: Armata Pharmaceuticals
  18. Drug profiles in the detailed report…..
  19. Inactive Products
  20. Bronchiectasis Key Companies
  21. Bronchiectasis Key Products
  22. Bronchiectasis- Unmet Needs
  23. Bronchiectasis- Market Drivers and Barriers
  24. Bronchiectasis- Future Perspectives and Conclusion
  25. Bronchiectasis Analyst Views
  26. Bronchiectasis Key Companies
  27. Appendix

About Us

DelveInsight is a leading healthcare-focused market research and consulting firm that provides clients with high-quality market intelligence and analysis to support informed business decisions. With a team of experienced industry experts and a deep understanding of the life sciences and healthcare sectors, we offer customized research solutions and insights to clients across the globe. Connect with us to get high-quality, accurate, and real-time intelligence to stay ahead of the growth curve.

Media Contact
Company Name: DelveInsight Business Research LLP
Contact Person: Yash Bhardwaj
Email: Send Email
Phone: 09650213330
Address:304 S. Jones Blvd #2432
City: Las Vegas
State: NV
Country: United States
Website: https://www.delveinsight.com/report-store/bronchiectasis-pipeline-insight

 

Press Release Distributed by ABNewswire.com

To view the original version on ABNewswire visit: Bronchiectasis Clinical Pipeline Demonstrates Strong Growth Backed by 15+ Active Industry Players | DelveInsight

Multiple Sclerosis Treatment Pipeline Witnesses Strong Innovation with 75+ Companies Advancing Novel Therapeutics | DelveInsight

DelveInsight’s “Multiple Sclerosis Pipeline Insight 2026” report provides comprehensive insights about 75+ companies and 80+ pipeline drugs in the Multiple Sclerosis pipeline landscape. It covers the Multiple Sclerosis pipeline drug profiles, including clinical and nonclinical stage products. It also covers the Multiple Sclerosis therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

Discover the latest drugs and treatment options in the Multiple Sclerosis Pipeline @ https://www.delveinsight.com/sample-request/multiple-sclerosis-pipeline-insight

Key Takeaways from the Multiple Sclerosis Pipeline Report

  • On May 19, 2026- Novartis Pharmaceuticals initiated a phase IV study in which breastfeeding mothers treated with ofatumumab and their babies are taking part for up to 1 year. The study consists of a Core Part and a Safety Follow-up Part. The Core Part includes a Screening period and a Sampling period. During the Screening period (up to 4 weeks), the study doctor will assess if mothers can join the study. The Sampling period, during which milk samples and a blood sample will be collected, will last for up to 12 weeks. The Safety Follow-up Part will last for about 9 months, to follow up on health and safety of mothers and their babies.
  • On May 15, 2026- Sanofi conducted a phase 3 study is to evaluate SC administration of frexalimab every 4 weeks (q4w) compared to IV administration of frexalimab q4w in male and female participants with RMS and nrSPMS (aged 18 to 60 years at the time of enrollment). People diagnosed with MS are eligible for enrollment as long as they meet all the inclusion criteria and none of the exclusion criteria.
  • DelveInsight’s Multiple Sclerosis pipeline report depicts a robust space with 75+ active players working to develop 80+ pipeline therapies for Multiple Sclerosis treatment.
  • The leading Multiple Sclerosis Companies such as Novartis, Sanofi, Immunic, Biocad, Apimeds, Genentech (Roche), Merck, AB Science, Apurano Pharmaceuticals, Biogen, Tiziana Life Sciences, Worg Pharmaceuticals, Antisense Therapeutics, RemeGen, Atara Biotherapeutics, Contineum Therapeutics, Stem Cell Medicine Ltd., Ever Supreme Bio Technology Co., Ltd., ImCyse and others.
  • Promising Multiple Sclerosis Therapies such as 11C-BMS-986196, ofatumumab, Fingolimod, Siponimod, elezanumab, Alemtuzumab, Tecfidera, and others.

Get insights into clinical trials, emerging therapies, and leading companies with DelveInsight @ Multiple Sclerosis Treatment Drugs

The Multiple Sclerosis Pipeline Report provides a disease overview, pipeline scenario, and therapeutic assessment of the key pipeline therapies in this domain. The Multiple Sclerosis Pipeline Report also highlights the unmet needs with respect to the Multiple Sclerosis.

Multiple Sclerosis Overview

Multiple Sclerosis is the most common neurological disorder in young adults, with symptoms usually occurring between the ages of 20 and 40 years. MS attacks the axons of the central nervous system, which are protected by myelin, commonly known as white matter. Relapsing–remitting MS: the most common form, affecting about 85% of MS patients. It is marked by flare-ups (relapses or exacerbations) of symptoms followed by periods of remission, when symptoms improve or disappear.

Multiple Sclerosis Emerging Drugs Profile

  • IMU-838: Immunic Therapeutics

Vidofludimus calcium (IMU-838) is a small molecule investigational drug under development as an oral tablet formulation for the treatment of relapsing-remitting multiple sclerosis, or RRMS, inflammatory bowel disease, or IBD, and other chronic inflammatory and autoimmune diseases. Bolstered by excellent clinical data from the phase II EMPhASIS trial, Immunic believed that vidofludimus calcium has the potential to demonstrate medically important advantages compared with other treatments, particularly for the early treatment of RMS patients, due to its placebo like safety profile and its robust anti-inflammatory and neuroprotective properties.

  • BIIB091: Biogen

BIIB091 selectively inhibits Burton’s tyrosine kinase (BTK), a non-receptor tyrosine kinase that regulates the development and signaling of B cells and myeloid cells hypothesized to contribute to MS pathogenesis. In addition, BTK has been demonstrated to play a key role in the activation of another cell of the immune system, the myeloid cells via another receptor of this cell (Fcγ receptor signaling (FcγRs)). Preclinical studies demonstrated BIB091 to be a high potency molecule with good drug-like properties and a safety/tolerability profile suitable for clinical development as a highly selective, reversible BTKi for treating autoimmune diseases such as MS. Currently, the drug is in the Phase II stage of its development for the treatment of Multiple sclerosis.

  • IMCY-0141: ImCyse

IMCY-0141 is the Company’s second clinical-stage compound. This Imotope is designed based on MOG (Myelin Oligodendrocyte Glycoprotein) with the aim to halt the progression of Multiple Sclerosis by stopping the body’s immune system from attacking the central nervous system and disrupting undesirable autoimmune responses that drive the destruction of the myelin sheath protecting the nerves. IMCY-0141 has shown promising results in several MS preclinical models, demonstrating an immune response that supports the proposed mode of action and inducing a memory response so that the treatment effect is long-lasting and requires less frequent dosing regimens. Also, if treatment is begun early enough, it has the potential to allow patients to live with minimal impact from the disease. Currently, the drug is in Phase I/II stage of its clinical trial for the treatment of multiple sclerosis.

  • CC-97540: Bristol-Myers Squibb

CC-97540 is an investigational drug developed by Bristol-Myers Squibb, designed as a selective, orally bioavailable tyrosine kinase 2 (TYK2) inhibitor. TYK2 is a member of the Janus kinase (JAK) family involved in the signaling pathways of several pro-inflammatory cytokines, including interleukin (IL)-12, IL-23, and type I interferons, which are implicated in autoimmune and inflammatory diseases. By selectively inhibiting TYK2 without significantly affecting other JAK isoforms, CC-97540 aims to reduce inflammation with potentially fewer side effects compared to broader JAK inhibitors. It is being evaluated for use in conditions such as psoriasis and systemic lupus erythematosus. Currently, the drug is in Phase I stage of its clinical trial for the treatment of multiple sclerosis.

Explore groundbreaking therapies and clinical trials in the Multiple Sclerosis Pipeline @ New Multiple Sclerosis Treatment Drugs

The Multiple Sclerosis Pipeline Report Provides Insights into

  • The report provides detailed insights about companies that are developing therapies for the treatment of Multiple Sclerosis with aggregate therapies developed by each company for the same.
  • It accesses the Different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for Multiple Sclerosis Treatment.
  • Multiple Sclerosis Companies are involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.
  • Multiple Sclerosis Drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type.
  • Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement and financing details for future advancement of the Multiple Sclerosis market

Multiple Sclerosis Companies

Novartis, Sanofi, Immunic, Biocad, Apimeds, Genentech (Roche), Merck, AB Science, Apurano Pharmaceuticals, Biogen, Tiziana Life Sciences, Worg Pharmaceuticals, Antisense Therapeutics, RemeGen, Atara Biotherapeutics, Contineum Therapeutics, Stem Cell Medicine Ltd., Ever Supreme Bio Technology Co., Ltd., ImCyse and others.

The Multiple Sclerosis pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as

  • Oral
  • Intravenous
  • Subcutaneous
  • Parenteral
  • Topical

Multiple Sclerosis Products have been categorized under various Molecule types such as,

  • Recombinant fusion proteins
  • Small molecule
  • Monoclonal antibody
  • Peptide
  • Polymer
  • Gene therapy

Learn about new drugs, pipeline developments, and key companies with DelveInsight’s expert analysis @ Multiple Sclerosis Market Drivers and Barriers

Scope of the Multiple Sclerosis Pipeline Report

  • Coverage- Global
  • Multiple Sclerosis Companies- Novartis, Sanofi, Immunic, Biocad, Apimeds, Genentech (Roche), Merck, AB Science, Apurano Pharmaceuticals, Biogen, Tiziana Life Sciences, Worg Pharmaceuticals, Antisense Therapeutics, RemeGen, Atara Biotherapeutics, Contineum Therapeutics, Stem Cell Medicine Ltd., Ever Supreme Bio Technology Co., Ltd., ImCyse and others.
  • Multiple Sclerosis Therapies- 11C-BMS-986196, ofatumumab, Fingolimod, Siponimod, elezanumab, Alemtuzumab, Tecfidera, and others.
  • Multiple Sclerosis Therapeutic Assessment by Product Type: Mono, Combination, Mono/Combination
  • Multiple Sclerosis Therapeutic Assessment by Clinical Stages: Discovery, Pre-clinical, Phase I, Phase II, Phase III

Download DelveInsight’s in-depth pipeline report today! @ Multiple Sclerosis Companies, Key Products and Unmet Needs

Table of Contents

  1. Introduction
  2. Executive Summary
  3. Multiple sclerosis: Overview
  4. Pipeline Therapeutics
  5. Therapeutic Assessment
  6. Multiple sclerosis – DelveInsight’s Analytical Perspective
  7. Late Stage Products (Phase III)
  8. IMU-838: Immunic Therapeutics
  9. Drug profiles in the detailed report…..
  10. Mid Stage Products (Phase II)
  11. BIIB091: Biogen
  12. Drug profiles in the detailed report…..
  13. Early Stage Products (Phase I)
  14. NeuroVax: Immune Response BioPharma
  15. Drug profiles in the detailed report…..
  16. Preclinical and Discovery Stage Products
  17. Drug name: Company name
  18. Drug profiles in the detailed report…..
  19. Inactive Products
  20. Multiple sclerosis Key Companies
  21. Multiple sclerosis Key Products
  22. Multiple sclerosis- Unmet Needs
  23. Multiple sclerosis- Market Drivers and Barriers
  24. Multiple sclerosis- Future Perspectives and Conclusion
  25. Multiple sclerosis Analyst Views
  26. Multiple sclerosis Key Companies
  27. Appendix

About Us

DelveInsight is a leading healthcare-focused market research and consulting firm that provides clients with high-quality market intelligence and analysis to support informed business decisions. With a team of experienced industry experts and a deep understanding of the life sciences and healthcare sectors, we offer customized research solutions and insights to clients across the globe. Connect with us to get high-quality, accurate, and real-time intelligence to stay ahead of the growth curve.

Media Contact
Company Name: DelveInsight Business Research LLP
Contact Person: Yash Bhardwaj
Email: Send Email
Phone: 09650213330
Address:304 S. Jones Blvd #2432
City: Las Vegas
State: NV
Country: United States
Website: https://www.delveinsight.com/report-store/multiple-sclerosis-pipeline-insight

 

Press Release Distributed by ABNewswire.com

To view the original version on ABNewswire visit: Multiple Sclerosis Treatment Pipeline Witnesses Strong Innovation with 75+ Companies Advancing Novel Therapeutics | DelveInsight

Graves’ Disease Therapeutics Market Size (7MM) was ~USD 4,400 million in 2023 and is projected to grow at a significant CAGR by 2034, estimates DelveInsight

DelveInsight’s “Graves’ Disease Market Insights, Epidemiology, and Market Forecast-2034′′ report offers an in-depth understanding of the Graves’ Disease, historical and forecasted epidemiology as well as the Graves’ Disease market trends in the United States, EU4 (Germany, Spain, Italy, France) the United Kingdom and Japan.

Explore Graves’ Disease Market Trends, treatment landscapes, and emerging therapies shaping the future @ https://www.delveinsight.com/sample-request/graves-disease-market

Key Takeaways from the Graves’ Disease Market Report

  • On May 26, 2026, Amgen initiated a clinical trial is to assess the efficacy of AMG 732 in participants with thyroid eye disease (TED) who are defined as primary nonresponders or relapsed during the safety follow-up in the parent trial (NCT06401044).
  • On May 22, 2026- Viridian Therapeutics Inc. announced a study arms by chance), double-masked (meaning study doctor and participant will not know which study arm participant is assigned to), controlled study that will include participants with TED of any duration. The key objectives of this study are to determine if VRDN-003 is safe and tolerable when administered as a series of subcutaneous (SC) injections every 4 weeks or every 8 weeks in participants with TED.
  • On May 22, 2026- Sanofi conducted a Phase 2, 2-arm study to measure the treatment effect and safety of rilzabrutinib dose 1 or rilzabrutinib dose 2 in participants with Graves’ disease, with and without Graves’ orbitopathy, aged 18 years or older.
  • On May 22, 2026- Immunovant Sciences GmbH initiated a Phase 2b study to assess the efficacy, safety, and tolerability of IMVT-1402 in adult participants with Graves’ disease (GD) who are hyperthyroid despite antithyroid drug (ATD) treatment.
  • Among the 7MM, the US accounted for approximately 48%, EU4 and the UK for 46%, and Japan for 6% of the total prevalent cases of Graves’ disease in 2023.
  • As per the DelveInsight estimates, it has been found that there were approximately 3,720,200 diagnosed prevalent cases of Graves’ disease in the 7MM in 2023.
  • In 2023, the manifestation of Graves’ disease in the US showed that Graves’ Ophthalmopathy captured the highest number of cases, i.e., approximately 584,400 cases.
  • In 2023, the gender-specific diagnosed prevalent cases of Graves’ disease in Japan were approximately 80,450 cases for males and approximately 321,800 cases for females.
  • The leading Graves’ Disease Companies such as Amgen (Horizon Therapeutics), Immunovant, Samsung Biologics, HanAll Biopharma, Roivant Sciences, Viridian Therapeutics, Argenx, Hoffmann-La Roche, Sling Therapeutics, Tourmaline Bio, Lassen Therapeutics, ACELYRIN and others.
  • Promising Graves’ Disease Therapies such as linsitinib, Batoclimab, Teprotumumab, VRDN-001 10 mg/kg, Satralizumab, IBI311, and others.

Discover which therapies are expected to grab the Graves’ Disease Market Share @ Graves’ Disease Treatment Market

Graves’ Disease Overview

Graves’ disease is an autoimmune disorder and the most common cause of hyperthyroidism, characterized by the overproduction of thyroid hormones due to the presence of thyroid-stimulating immunoglobulins that activate the thyroid-stimulating hormone (TSH) receptor. This excessive hormone secretion leads to a hypermetabolic state, resulting in symptoms such as weight loss, heat intolerance, palpitations, anxiety, tremors, and fatigue, along with a diffusely enlarged thyroid gland (goiter).

Graves’ Disease Epidemiology Segmentation in the 7MM

  • Total Prevalent Cases of Graves’ Disease
  • Total Diagnosed Prevalent Cases of Graves’ Disease
  • Gender-specific Cases of Graves’ Disease
  • Graves’ Disease Cases by Manifestations

Download the report to understand which factors are driving Graves’ Disease epidemiology trends @ Graves’ Disease Prevalence

Graves’ Disease Drugs Uptake and Pipeline Development Activities

The drugs uptake section focuses on the rate of uptake of the potential drugs recently launched in the Graves’ Disease market or expected to get launched during the study period. The analysis covers Graves’ Disease market uptake by drugs, patient uptake by therapies, and sales of each drug. Moreover, the therapeutics assessment section helps understand the drugs with the most rapid uptake and the reasons behind the maximal use of the drugs. Additionally, it compares the drugs based on market share. The report also covers the Graves’ Disease Pipeline Development Activities. It provides valuable insights about different therapeutic candidates in various stages and the key companies involved in developing targeted therapeutics. It also analyzes recent developments such as collaborations, acquisitions, mergers, licensing patent details, and other information for emerging therapies.

Graves’ Disease Therapies and Companies

• Sling Therapeutics, Inc.: linsitinib

• Immunovant Sciences GmbH: Batoclimab

• Amgen: Teprotumumab

• Viridian Therapeutics Inc.:- VRDN-001 10 mg/kg

• Hoffmann-La Roche: Satralizumab

Graves’ Disease Market Outlook

There are three main treatments for Graves’ disease: ATD medications, thyroidectomy, and radioactive iodine therapy. ATD medications prevent the biosynthesis of the thyroid hormone by blocking iodide, the salted or reduced form of iodine, from interacting with thyroglobulin, thus diminishing the amount of hormone produced. Methimazole is the most widely used ATD medication, with a long half-life and low side effects. Another is carbimazole has been approved in European countries but is not approved in the United States. It is an inactive drug that is metabolized in the blood into the active methimazole thus it is less potent. And the last is propylthiouracil, which is the least potent of the available antithyroid medications. Approved in the United States and Europe, propylthiouracil is the initial treatment choice during the first trimester of pregnancy because of the low placental transfer. Propylthiouracil was, for many years, the first-choice ATD in both the USA and South America. But now the American Thyroid Association (ATA) recommends Methimazole over Propylthiouracil. Methimazole is used in most European countries and Japan, whereas carbimazole is mainly used in the UK.

Marketed Graves’ disease Drugs

• TEPEZZA (Teprotumumab-Trbw): Amgen (Horizon Therapeutics)

Teprotumumab, an insulin-like Growth Factor-1 receptor (IGF-1R) inhibitor, is a fully human IgG1 monoclonal antibody produced in Chinese hamster (CHO-DG44) cells with a molecular weight of approximately 148 KD. In January 2020, the US FDA approved TEPEZZA for the treatment of TED after an accelerated Priority Review. And recently, in September 2024, the drug was approved by Japan’s Ministry of Health, Labour, and Welfare (MHLW) for the treatment of active Graves’ orbitopathy. Additionally, in April 2024, Amgen announced its plans to submit a Marketing Authorization Application (MAA) for teprotumumab to the European Medicines Agency (EMA) in the near future. TEPEZZA is currently under investigation in Phase III clinical trials for patients with moderate-to-severe active Graves’ orbitopathy as well as those with chronic TED characterized by a low Clinical Activity Score (CAS). Additionally, Amgen is exploring its potential for subcutaneous administration.

Get In-Depth Knowledge on Acute on Graves’ disease Market Trends and Forecasts with DelveInsight @ Graves’ disease Market Drivers and Barriers

Emerging Graves’ disease Drugs

• IMVT-1401 (batoclimab, RVT-1401): Immunovant, Samsung Biologics, HanAll Biopharma, and Roivant Sciences

Immunovant’s first investigational product, batoclimab (IMVT-1401), is a novel, fully human monoclonal antibody targeting the neonatal FcRn. In nonclinical studies and clinical trials, batoclimab has been observed to reduce IgG antibody levels. High levels of pathogenic IgG antibodies drive a variety of autoimmune diseases, and, as a result, this product candidate has the potential to address a variety of IgG-mediated autoimmune diseases as a self-administered SC injection. Currently, batoclimab is being developed as a low-volume SC injection for the treatment of a variety of IgG-mediated autoimmune disorders, including myasthenia gravis, TED, chronic inflammatory demyelinating polyneuropathy, and Graves’ disease. The drug is currently in Phase III developmental stage. Recently, in September 2024, Immunovant received Investigational New Drug (IND) clearance from the US FDA for IMVT-1402 in Graves’ disease patients who remain hyperthyroid despite treatment with antithyroid drugs. Furthermore, Immunovant plans to initiate clinical trials of IMVT-1402 in a total of ten indications by March 2026.

• VRDN-001 (veligrotug): Viridian Therapeutics

Viridian’s lead product candidate, VRDN-001, is a differentiated monoclonal antibody targeting Insulin-like Growth Factor-1 Receptor (IGF-1R), a clinically and commercially validated target for the treatment of Graves’ ophthalmopathy. In preclinical studies, VRDN-001 had shown to be a full antagonist of IGF-1R, with complete receptor blockade than other anti-IGF-1R antibodies, including the only approved Graves’ Ophthalmopathy therapy. Currently, the drug is currently being evaluated in various Phase III trials for the treatment of Graves’ ophthalmopathy. According to a corporate presentation published in November 2024, the potential PDUFA date and launch of veligrotug are expected in 2H 2026.

Scope of the Graves’ Disease Market Report

• Coverage: 7MM

• Study Period: 2020-2034

• Graves’ Disease Companies- Amgen (Horizon Therapeutics), Immunovant, Samsung Biologics, HanAll Biopharma, Roivant Sciences, Viridian Therapeutics, Argenx, Hoffmann-La Roche, Sling Therapeutics, Tourmaline Bio, Lassen Therapeutics, ACELYRIN and others.

• Graves’ Disease Therapies- linsitinib, Batoclimab, Teprotumumab, VRDN-001 10 mg/kg, Satralizumab, IBI311, and others.

• Graves’ Disease Therapeutic Assessment: Graves’ Disease current marketed and Graves’ Disease emerging therapies

• Graves’ Disease Market Dynamics: Graves’ Disease market drivers and Graves’ Disease market barriers

• Competitive Intelligence Analysis: SWOT analysis, PESTLE analysis, Porter’s five forces, BCG Matrix, Market entry strategies

• Graves’ Disease Unmet Needs, KOL’s views, Analyst’s views, Graves’ Disease Market Access and Reimbursement

Discover more about Graves’ Disease Drugs in development @ Graves’ Disease Ongoing Clinical Trials

Table of Contents

1. Graves’ Disease Market Report Introduction

2. Executive Summary for Graves’ Disease

3. SWOT analysis of Graves’ Disease

4. Graves’ Disease Patient Share (%) Overview at a Glance

5. Graves’ Disease Market Overview at a Glance

6. Graves’ Disease Disease Background and Overview

7. Graves’ Disease Epidemiology and Patient Population

8. Country-Specific Patient Population of Graves’ Disease

9. Graves’ Disease Current Treatment and Medical Practices

10. Graves’ Disease Unmet Needs

11. Graves’ Disease Emerging Therapies

12. Graves’ Disease Market Outlook

13. Country-Wise Graves’ Disease Market Analysis (2020-2034)

14. Graves’ Disease Market Access and Reimbursement of Therapies

15. Graves’ Disease Market Drivers

16. Graves’ Disease Market Barriers

17. Graves’ Disease Appendix

18. Graves’ Disease Report Methodology

19. DelveInsight Capabilities

20. Disclaimer

21. About DelveInsight

About Us

DelveInsight is a leading healthcare-focused market research and consulting firm that provides clients with high-quality market intelligence and analysis to support informed business decisions. With a team of experienced industry experts and a deep understanding of the life sciences and healthcare sectors, we offer customized research solutions and insights to clients across the globe. Connect with us to get high-quality, accurate, and real-time intelligence to stay ahead of the growth curve.

Media Contact
Company Name: DelveInsight Business Research LLP
Contact Person: Yash Bhardwaj
Email: Send Email
Phone: 09650213330
Address:304 S. Jones Blvd #2432
City: Las Vegas
State: NV
Country: United States
Website: https://www.delveinsight.com/report-store/graves-disease-market

 

Press Release Distributed by ABNewswire.com

To view the original version on ABNewswire visit: Graves’ Disease Therapeutics Market Size (7MM) was ~USD 4,400 million in 2023 and is projected to grow at a significant CAGR by 2034, estimates DelveInsight

MASH Therapeutics Market Size (7MM) was ~USD 3 Billion in 2025 and it is projected to grow at a significant CAGR by 2036, estimates Delveinsight

DelveInsight’s “MASH Treatment Market Insights, Epidemiology, and Market Forecast – 2036” report delivers an in-depth understanding of MASH, historical and forecasted epidemiology, as well as the MASH market trends in the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan.

Discover which therapies are expected to grab the MASH Market Share @ https://www.delveinsight.com/sample-request/metabolic-dysfunction-associated-steatohepatitis-mash-market

Key Takeaways from the MASH Market Report

  • According to DelveInsight’s estimates, there were more than ~200 million prevalent cases of MASLD (formerly known as NAFLD) in the 7MM in 2025, including ~30 million prevalent cases of MASH. Of the total MASH cases, ~8 million were diagnosed in the 7MM.
  • Among the 7MM, the US had the highest number of diagnosed prevalent MASH cases, with ~5 million cases in 2025, a figure projected to increase by 2036.
  • In 2025, EU4 and the UK accounted for ~3 million diagnosed prevalent cases of MASH, with Germany having the highest at ~795 thousand cases, followed by Italy with ~630 thousand cases. In contrast, Spain had the least, with ~350 thousand cases.
  • In 2025, the UK had ~580 thousand diagnosed prevalent cases of MASH.
  • In 2025, Japan recorded ~800 thousand diagnosed prevalent cases of MASH, a number expected to rise by 2036.
  • The leading MASH Companies such as Inventiva Pharma, Novo Nordisk A/S, Cirius Therapeutics, Inc., Akero Therapeutics, Inc., 89bio, Inc., Boehringer Ingelheim/Zealand Pharma, Galectin Therapeutics Inc., Lipocine Inc, Viking Therapeutics, Inc., Eli Lilly and Company, Boston Pharmaceuticals, Pfizer, HighTide Biopharma, CytoDyn, Inc., Merck & Co./Hanmi Pharmaceutical, Hepagene (Shanghai) Co., Ltd., Hepion Pharmaceuticals, Inc., Enyo Pharmaceuticals, Gilead Sciences, Poxel SA, Zydus Therapeutics, Sagimet Biosciences Inc., Ionis Pharmaceuticals, and Corcept Therapeutics and others.
  • Promising MASH Pipeline Therapies such as TVB-2640, Survodutide, Miricorilant (Cohort B), Efimosfermin, Pegozafermin, DD01, ALG-055009, and others.

Stay ahead in the MASH Therapeutics Market with DelveInsight’s Strategic Report @ MASH Treatment Market

MASH Epidemiology Segmentation in the 7MM

  • Total MASH Prevalent Cases
  • Total Diagnosed Prevalent Cases
  • MASH Severity-specific Diagnosed Prevalent Cases

Download the report to understand which factors are driving MASH Epidemiology trends @ MASH Prevalence

MASH Marketed Drugs

  • REZDIFFRA (resmetirom): Madrigal Pharmaceuticals

REZDIFFRA (resmetirom), a Thyroid Hormone Receptor-beta (THR-ß) agonist, is approved for treating adults with noncirrhotic MASH and moderate to advanced liver fibrosis (F2-F3), in conjunction with diet and exercise. It received accelerated approval due to improvements in MASH and fibrosis. In March 2024, the US FDA approved REZDIFFRA for adults with noncirrhotic MASH with moderate to advanced liver fibrosis (F2 to F3).

MASH Emerging Drugs

  • Efruxifermin (EFX): Akero Therapeutics

Efruxifermin (EFX), Akero Therapeutics’ leading candidate for MASH, is an engineered Fc-FGF21 fusion protein mimicking the biological activity of native FGF21. EFX has shown promise in reducing liver fat, inflammation, and fibrosis, while enhancing insulin sensitivity and lipid metabolism. It offers once-weekly dosing and a favorable tolerability profile in clinical trials. Currently, EFX is being evaluated in three Phase III studies, with encouraging results from Phase II trials showing its potential to reverse fibrosis and improve liver function. The Phase III SYNCHRONY study is expected to provide results in 2026.

  • VK2809 (TRß Agonist): Viking Therapeutics

VK2809 is an orally available, liver-targeted agonist of the Thyroid Hormone Beta Receptor (TRß), designed to specifically modulate lipid metabolism. By selectively activating TRß in liver tissue, VK2809 aims to improve cholesterol and lipoprotein levels through the upregulation of genes involved in lipid clearance. The compound has shown significant therapeutic potential in lipid disorders, meeting both primary and secondary endpoints in the Phase IIb VOYAGE study for patients with NASH/MASH and fibrosis, as well as in a Phase IIa study for patients with elevated LDL-C and MASLD.

  • Efimosfermin alfa (formerly BOS-580): Boston Pharmaceuticals

Efimosfermin alfa (BOS-580), developed by Boston Pharmaceuticals, is a long-acting variant of FGF21 designed to regulate metabolic pathways, reducing liver fat, inflammation, and fibrosis in MASH patients. Manufactured in mammalian cells for human-like glycosylation, it is administered as a once-monthly subcutaneous injection. BOS-580 is currently undergoing Phase II trials for MASH treatment. In September 2020, Boston Pharmaceuticals licensed the genetically engineered FGF21 variant from Novartis, positioning it as a potential best-in-class treatment for MASH.

To learn more about MASH Treatment guidelines, visit @ MASH Clinical Trials Assessment

MASH Companies

Inventiva Pharma, Novo Nordisk A/S, Cirius Therapeutics, Inc., Akero Therapeutics, Inc., 89bio, Inc., Boehringer Ingelheim/Zealand Pharma, Galectin Therapeutics Inc., Lipocine Inc, Viking Therapeutics, Inc., Eli Lilly and Company, Boston Pharmaceuticals, Pfizer, HighTide Biopharma, CytoDyn, Inc., Merck & Co./Hanmi Pharmaceutical, Hepagene (Shanghai) Co., Ltd., Hepion Pharmaceuticals, Inc., Enyo Pharmaceuticals, Gilead Sciences, Poxel SA, Zydus Therapeutics, Sagimet Biosciences Inc., Ionis Pharmaceuticals, and Corcept Therapeutics and others.

MASH Drugs Market Insights

Efruxifermin (EFX) is an investigational Fc-FGF21 fusion protein developed by Akero Therapeutics for the treatment of MASH. Designed to mimic the biological activity of FGF21, EFX aims to address key drivers of MASH by reducing liver fat and inflammation, reversing fibrosis, and improving insulin sensitivity and lipid metabolism. In a 96-week Phase IIb study, 39% of patients with compensated cirrhosis due to MASH experienced a reversal of cirrhosis without worsening of the disease, compared to 15% in the placebo group. These promising results have led to the initiation of the Phase III SYNCHRONY clinical program, which includes trials evaluating EFX in patients with pre-cirrhotic MASH (F2-F3 fibrosis) and those with compensated cirrhosis (F4) due to MASH.

MASH Treatment Market

The MASH treatment landscape is rapidly evolving, particularly with the USFDA’s accelerated approval of Madrigal’s REZDIFFRA, now considered a key therapy for patients with moderate to advanced liver fibrosis. This selective thyroid hormone receptor-beta agonist has shifted the approach from invasive liver biopsies to non-invasive diagnostic methods, improving patient access to treatment. The landscape is further shaped by a diverse pipeline of therapies targeting various mechanisms, such as FXR agonists, PPAR modulators, and GLP-1 receptor agonists, with clinical trials exploring combination therapies to address the complex nature of the disease. As researchers focus on personalized medicine and better patient stratification, the priority remains refining treatment strategies while navigating challenges in trial recruitment and regulatory requirements. The combination of emerging therapies and existing lifestyle interventions continues to influence clinical practice in managing MASH/NASH.

Learn more about the FDA-approved drugs for MASH @ Drugs for MASH Treatment

Scope of the MASH Market Report

  • Coverage- 7MM
  • Study Period- 2022-2036
  • Forecast Period- 2026-2036
  • MASH Companies- Inventiva Pharma, Novo Nordisk A/S, Cirius Therapeutics, Inc., Akero Therapeutics, Inc., 89bio, Inc., Boehringer Ingelheim/Zealand Pharma, Galectin Therapeutics Inc., Lipocine Inc, Viking Therapeutics, Inc., Eli Lilly and Company, Boston Pharmaceuticals, Pfizer, HighTide Biopharma, CytoDyn, Inc., Merck & Co./Hanmi Pharmaceutical, Hepagene (Shanghai) Co., Ltd., Hepion Pharmaceuticals, Inc., Enyo Pharmaceuticals, Gilead Sciences, Poxel SA, Zydus Therapeutics, Sagimet Biosciences Inc., Ionis Pharmaceuticals, and Corcept Therapeutics and others.
  • MASH Pipeline Therapies- TVB-2640, Survodutide, Miricorilant (Cohort B), Efimosfermin, Pegozafermin, DD01, ALG-055009, and others.
  • MASH Market Dynamics: MASH Market Drivers and Barriers
  • MASH Market Access and Reimbursement, Unmet Needs and Future Perspectives

Table of Contents

  1. Key Insights
  2. MASH Market Report Introduction
  3. MASH Market Overview at a Glance
  4. Methodology of Epidemiology and Market
  5. Executive Summary
  6. Key Events
  7. Disease Background and Overview
  8. MASH Epidemiology and Patient Population
  9. Patient Journey
  10. MASH Marketed Drugs
  11. MASH Emerging Drugs
  12. MASH – 7MM Market Analysis
  13. Key Opinion Leaders’ Views
  14. MASH Unmet Needs
  15. MASH SWOT Analysis
  16. MASH Market Access and Reimbursement
  17. Appendix
  18. DelveInsight Capabilities
  19. Disclaimer
  20. About DelveInsight

About Us

DelveInsight is a leading healthcare-focused market research and consulting firm that provides clients with high-quality market intelligence and analysis to support informed business decisions. With a team of experienced industry experts and a deep understanding of the life sciences and healthcare sectors, we offer customized research solutions and insights to clients across the globe. Connect with us to get high-quality, accurate, and real-time intelligence to stay ahead of the growth curve.

Media Contact
Company Name: DelveInsight Business Research LLP
Contact Person: Yash Bhardwaj
Email: Send Email
Phone: 09650213330
Address:304 S. Jones Blvd #2432
City: Las Vegas
State: NV
Country: United States
Website: https://www.delveinsight.com/report-store/metabolic-dysfunction-associated-steatohepatitis-mash-market

 

Press Release Distributed by ABNewswire.com

To view the original version on ABNewswire visit: MASH Therapeutics Market Size (7MM) was ~USD 3 Billion in 2025 and it is projected to grow at a significant CAGR by 2036, estimates Delveinsight

Osteoarthritis Pipeline Continues Rapid Expansion with 100+ Companies Advancing Musculoskeletal Programs | DelveInsight

DelveInsight’s, “Osteoarthritis Pipeline Insights 2026” report provides comprehensive insights about 100+ companies and 110+ pipeline drugs in Osteoarthritis pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

Download DelveInsight’s comprehensive Osteoarthritis Pipeline Report to explore emerging therapies @ https://www.delveinsight.com/sample-request/osteoarthritis-pipeline-insight

Key Takeaways from the Osteoarthritis Pipeline Report

  • On May 22, 2026, Eli Lilly and Company initiated a phase 3 study will see how well and safely orforglipron works in people with obesity or overweight who have osteoarthritis (OA) of the knee with pain. Participation in the study will last about 74 weeks.
  • On May 06, 2026, Kolon TissueGene Inc. announced a phase 3 study to determine the efficacy and safety of TG-C in subjects with Kellgren and Lawrence Grade 2 or 3 Osteoarthritis of the Knee, Osteoarthritis Research Society International (OARSI) medial joint space narrowing (JSN) Grade 1 or 2 of the knee joint. TG-C is to be administered by a single intra-articular injection to the damaged joint area via ultrasound guidance. Patients will be followed for 24 months for safety and efficacy.
  • DelveInsight’s Osteoarthritis pipeline report depicts a robust space with 100+ active players working to develop 110+ pipeline therapies for Osteoarthritis treatment.
  • The leading Osteoarthritis Companies such as Biosplice Therapeutics, Cynata Therapeutics, Bone Therapeutics S.A, Regeneron Pharmaceuticals, Techfields Pharma, Ampio Pharmaceuticals, Asahi Kasei Pharma, Taiwan Bio Therapeutics, OliPass Corporation, Bioventus, Medipost, LG Chem, ICM Biotech, Cells for Cells SA, GWOXI Stem Cell Applied Technology, UnicoCell Biomed, Magellan Biologicals, Levicept, Arthrogen, Personalized Stem Cells, Peptinov, Orient Europharma, ZYUS Life Sciences, Lubris Biopharma, Saol Therapeutics, Ageless Biotech, Synartro AB, Plakous Therapeutics, Ribomic, Meluha Therapeutics and others.
  • Promising Osteoarthritis Pipeline Therapies such as MK0663, Etoricoxib, Diacerein, Celecoxib, RTX-GRT7039, Naproxcinod, Naproxen, LY3857210, LY3556050, LY3016859, Ibuprofen, Voltaren® Gel, Gevokizumab and others.

Access DelveInsight’s in-depth Osteoarthritis Pipeline Analysis for a closer look at promising breakthroughs @ Osteoarthritis Clinical Trials and Studies

Osteoarthritis Overview

Osteoarthritis is the most common form of arthritis. Some people call it degenerative joint disease or “wear and tear” arthritis. It occurs most frequently in the hands, hips, and knees. With OA, the cartilage within a joint begins to break down and the underlying bone begins to change. These changes usually develop slowly and get worse over time. OA can cause pain, stiffness, and swelling. In some cases it also causes reduced function and disability; some people are no longer able to do daily tasks or work. Osteoarthritis is the most common type of arthritis, characterized by the gradual breakdown of cartilage in joints, leading to pain, stiffness, and swelling. Symptoms often include joint pain that worsens with activity and improves with rest, stiffness lasting less than 30 minutes after inactivity, and a sensation of joint instability or looseness. Affected joints may also produce a grinding or creaking sound during movement, and swelling can occur, particularly after prolonged use.

Osteoarthritis Emerging Drugs Profile

  • Lorecivivint: Biosplice Therapeutics

Lorecivivint (SM04690) is a small-molecule CLK/DYRK1A inhibitor that modulates Wnt and inflammatory pathways and is in development as a potential disease-modifying osteoarthritis drug. Vehicle-controlled preclinical data suggest that lorecivivint has a dual mechanism of action with three potential effects on joint health: reduction of inflammation, slowing of cartilage breakdown, and generation of cartilage. The drug is currently in Phase III stage of clinical trial evaluation to treat the patients suffering from osteoarthritis.

  • EP-104IAR: Eupraxia Pharmaceuticals

Eupraxia’s lead product candidate, EP-104IAR, is designed to meet the significant unmet medical need and market demand for long-lasting disease relief in multiple indications benefitting from highly localized and longer delivery of corticosteroids. The lead indication is for pain relief in knee OA. EP-104IAR is designed to prolong the duration of pain relief with fewer unwanted side effects. It encapsulates a highly potent corticosteroid (fluticasone propionate) within a microns-thin polymer membrane, part of Eupraxia’s patented technology platform. Injected into the knee, EP-104IAR is designed to diffuse the corticosteroid slowly into the knee joint providing local therapeutic concentrations for up to six months. This has the potential dual advantage of providing longer duration of pain relief with fewer systemic side effects. Currently, the drug is in Phase II stage of its clinical trial for the treatment of OA.

  • DFV890: Novartis

DFV890 is a small molecule, NOD-like receptor protein 3 (NLRP3) antagonist being developed by Novartis for the treatment of various inflammatory conditions. It is currently being evaluated in several phase I and II clinical trials, including studies in myeloid diseases, knee osteoarthritis, COVID-19, and cardiovascular disease. DFV890 works by inhibiting the NLRP3 protein, which plays a key role in the activation of the inflammatory response. Currently, the drug is in Phase II stage of its clinical trial for the treatment of OA.

  • 4P004: 4P-Pharma

4P004 is a GLP-1 analog, a potential first-in-class disease modifier drug for osteoarthritis (DMOAD), showing anti-inflammatory, anti-catabolic and anabolic properties. 4P004 was developed in collaboration with the team of Prof. Francis Berenbaum and SATT Lutech. 4P004 is owned by 4P-Pharma’s SPV – 4Moving Biotech. Currently, the drug is in Phase II stage of its clinical trial for the treatment of OA.

  • GNSC 001: Genascence

GNSC-001 is a genetic medicine – a recombinant adeno-associated viral vector expressing an optimized form of IL-1Ra, a naturally occurring protein that blocks interleukin-1 (IL-1) signaling. IL-1 is considered one of the key mediators involved in the pathogenesis of OA, causing inflammation, joint pain, as well as cartilage destruction. GNSC-001 is designed to offer long-term, sustained inhibition of IL-1 following a single injection into the affected joint. Currently, the drug is in Phase I stage of its clinical trial for the treatment of OA.

The Osteoarthritis Pipeline report provides insights into

  • The report provides detailed insights about companies that are developing therapies for the treatment of Osteoarthritis with aggregate therapies developed by each company for the same.
  • It accesses the Different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for Osteoarthritis Treatment.
  • Osteoarthritis Companies are involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.
  • Osteoarthritis Drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type.
  • Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement and financing details for future advancement of the Osteoarthritis market.

Get a detailed analysis of the latest innovations in the Osteoarthritis pipeline @ Osteoarthritis Unmet Needs

Osteoarthritis Companies

Biosplice Therapeutics, Cynata Therapeutics, Bone Therapeutics S.A, Regeneron Pharmaceuticals, Techfields Pharma, Ampio Pharmaceuticals, Asahi Kasei Pharma, Taiwan Bio Therapeutics, OliPass Corporation, Bioventus, Medipost, LG Chem, ICM Biotech, Cells for Cells SA, GWOXI Stem Cell Applied Technology, UnicoCell Biomed, Magellan Biologicals, Levicept, Arthrogen, Personalized Stem Cells, Peptinov, Orient Europharma, ZYUS Life Sciences, Lubris Biopharma, Saol Therapeutics, Ageless Biotech, Synartro AB, Plakous Therapeutics, Ribomic, Meluha Therapeutics and others.

Osteoarthritis Pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as

  • Oral
  • Intravenous
  • Subcutaneous
  • Parenteral
  • Topical

Osteoarthritis Products have been categorized under various Molecule types such as

  • Recombinant fusion proteins
  • Small molecule
  • Monoclonal antibody
  • Peptide
  • Polymer
  • Gene therapy

Download DelveInsight’s latest report to gain strategic insights into upcoming Osteoarthritis Therapies @ Osteoarthritis Market Drivers and Barriers, and Future Perspectives

Scope of the Osteoarthritis Pipeline Report

  • Coverage- Global
  • Osteoarthritis Companies- Biosplice Therapeutics, Cynata Therapeutics, Bone Therapeutics S.A, Regeneron Pharmaceuticals, Techfields Pharma, Ampio Pharmaceuticals, Asahi Kasei Pharma, Taiwan Bio Therapeutics, OliPass Corporation, Bioventus, Medipost, LG Chem, ICM Biotech, Cells for Cells SA, GWOXI Stem Cell Applied Technology, UnicoCell Biomed, Magellan Biologicals, Levicept, Arthrogen, Personalized Stem Cells, Peptinov, Orient Europharma, ZYUS Life Sciences, Lubris Biopharma, Saol Therapeutics, Ageless Biotech, Synartro AB, Plakous Therapeutics, Ribomic, Meluha Therapeutics and others.
  • Osteoarthritis Pipeline Therapies- MK0663, Etoricoxib, Diacerein, Celecoxib, RTX-GRT7039, Naproxcinod, Naproxen, LY3857210, LY3556050, LY3016859, Ibuprofen, Voltaren® Gel, Gevokizumab and others.
  • Osteoarthritis Therapeutic Assessment by Product Type: Mono, Combination, Mono/Combination
  • Osteoarthritis Therapeutic Assessment by Clinical Stages: Discovery, Pre-clinical, Phase I, Phase II, Phase III

Which companies are leading the race in Osteoarthritis drug development? @ Osteoarthritis Emerging Drugs and Major Companies

Table of Contents

  1. Introduction
  2. Executive Summary
  3. Osteoarthritis: Overview
  4. Pipeline Therapeutics
  5. Therapeutic Assessment
  6. Osteoarthritis– DelveInsight’s Analytical Perspective
  7. Late Stage Products (Phase III)
  8. Lorecivivint: Biosplice Therapeutics
  9. Mid Stage Products (Phase II)
  10. EP-104IAR: Eupraxia Pharmaceuticals
  11. Early Stage Products (Phase I)
  12. GNSC 001: Genascence
  13. Preclinical and Discovery Stage Products
  14. Drug name: Company name
  15. Inactive Products
  16. Osteoarthritis Key Companies
  17. Osteoarthritis Key Products
  18. Osteoarthritis- Unmet Needs
  19. Osteoarthritis- Market Drivers and Barriers
  20. Osteoarthritis- Future Perspectives and Conclusion
  21. Osteoarthritis Analyst Views
  22. Osteoarthritis Key Companies
  23. Appendix

About Us

DelveInsight is a leading healthcare-focused market research and consulting firm that provides clients with high-quality market intelligence and analysis to support informed business decisions. With a team of experienced industry experts and a deep understanding of the life sciences and healthcare sectors, we offer customized research solutions and insights to clients across the globe. Connect with us to get high-quality, accurate, and real-time intelligence to stay ahead of the growth curve.

Media Contact
Company Name: DelveInsight Business Research LLP
Contact Person: Yash Bhardwaj
Email: Send Email
Phone: 09650213330
Address:304 S. Jones Blvd #2432
City: Las Vegas
State: NV
Country: United States
Website: https://www.delveinsight.com/report-store/osteoarthritis-pipeline-insight

 

Press Release Distributed by ABNewswire.com

To view the original version on ABNewswire visit: Osteoarthritis Pipeline Continues Rapid Expansion with 100+ Companies Advancing Musculoskeletal Programs | DelveInsight

Paroxysmal Nocturnal Hemoglobinuria Clinical Trial Pipeline Gains Momentum: 20+ Companies Lead the Charge in Pioneering New Treatments | DelveInsight

DelveInsight’s, “Paroxysmal Nocturnal Haemoglobinuria Pipeline Insight 2026” report provides comprehensive insights about 20+ companies and 25+ pipeline drugs in Paroxysmal Nocturnal Hemoglobinuria pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

Stay ahead in understanding the Paroxysmal Nocturnal Hemoglobinuria Treatment Landscape @ https://www.delveinsight.com/sample-request/paroxysmal-nocturnal-hemoglobinuria-pipeline-insight

Key Takeaways from the Paroxysmal Nocturnal Hemoglobinuria Pipeline Report

  • On May 26, 2026, Regeneron Pharmaceuticals announced a study is researching a treatment combination with two experimental drugs called pozelimab and cemdisiran referred to as “study drugs”. Researchers are looking for a better way to treat Paroxysmal Nocturnal Hemoglobinuria (PNH).
  • On May 14, 2026, Hoffmann-La Roche initiated a Phase I/II, first-in-human study consisting of four sequential parts and an open-label extension (OLE). The safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of single doses of crovalimab will be evaluated in healthy volunteers (HV) during part 1. The safety, tolerability, PK and PD of multiple doses of crovalimab will be evaluated in participants with paroxysmal nocturnal hemoglobinuria (PNH) in parts 2, 3, 4, and OLE of the study. Efficacy of crovalimab will be evaluated in Parts 2, 3, and 4.
  • On May 08, 2026, Novartis Pharmaceuticals conducted a phase 3 study to characterize long-term safety, tolerability and efficacy of iptacopan and to provide access to iptacopan to patients with PNH who have completed Novartis-sponsored Phase 2 or 3 studies with iptacopan.
  • DelveInsight’s Paroxysmal Nocturnal Hemoglobinuria pipeline report depicts a robust space with 20+ active players working to develop 25+ pipeline therapies for Paroxysmal Nocturnal Hemoglobinuria treatment.
  • The leading Paroxysmal Nocturnal Hemoglobinuria Companies such as Hoffmann-La Roche, Apellis Pharmaceuticals, Regeneron Pharmaceuticals, Biocad, AKARI Therapeutics, Alexion Pharmaceuticals, Novartis Pharmaceuticals, Amgen, BioCryst Pharmaceuticals, MorphoSys, Ra Pharmaceuticals, Alnylam Pharmaceuticals, Arrowhead Pharmaceuticals, Wuhan Createrna Science and Technology, CANbridge, Attune Pharmaceuticals, RallyBio and others.
  • Promising Paroxysmal Nocturnal Hemoglobinuria Pipeline Therapies such as HSK39297 tablets, Coversin, MY008211A tablets, Eculizumab Injection, Pegcetacoplan, Crovalimab, Ravulizumab, Iptacopan, LNP023, and others.

Gain in-depth knowledge of key clinical trials, emerging drugs @ Paroxysmal Nocturnal Hemoglobinuria Ongoing Clinical Trials Assessment

Paroxysmal Nocturnal Haemoglobinuria Overview

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare acquired, life-threatening disease of the blood. The disease is characterized by complement-mediated hemolysis with or without hemoglobinuria, an increased susceptibility to thrombotic episodes and/or some degree of bone marrow dysfunction. PNH leads to excessive breakdown of red blood cells, leading to the release of a large amount of haemoglobin into the urine. Symptoms and signs of PNH include: fatigue; dark red/brown urine; difficulty swallowing, abdominal pain, infections, and bruising. The principal studies used to establish the diagnosis of PNH are flow cytometry of peripheral blood and bone marrow analysis. PNH typically starts from the early thirties to the mid‐forties, and often persisting for decades, with a continued dependence on blood transfusions in a proportion of patients. The appropriate treatment for PNH depends on the severity of symptoms. The mainstay of PNH treatment is the drug eculizumab (Soliris).

Paroxysmal Nocturnal Hemoglobinuria Emerging Drugs Profile

  • Crovalimab: Hoffman-La-Roche

Crovalimab (RG6107) is a humanised complement inhibitor C5 monoclonal antibody discovered by Chugai using recycling antibody technology. By blocking the cleavage of C5 to C5a and C5b, it is expected to inhibit complement activation, which is the cause of a number of diseases. As the complement system is a key innate immune defense mechanism, we plan to study the potential of this antibody in a broader range of complement-mediated diseases. A phase III clinical trial is evaluating crovalimab for the treatment of paroxysmal nocturnal hemoglobinuria.

  • Pozelimab: Regeneron Pharmaceuticals

Pozelimab is an investigational, fully-human monoclonal antibody designed to block complement factor C5 and prevent the destruction of red blood cells (hemolysis) that cause the symptoms of PNH and other diseases mediated by complement pathway activity. It is an IgG4 antibody that binds with high affinity to wild-type and variant human C5 and blocks its activity. Pozelimab was invented using Regeneron’s proprietary VelocImmune technology, which uses a unique genetically-humanized mouse to produce optimized fully-human antibodies. Pozelimab is currently under clinical development, and its safety and efficacy have not been evaluated by any regulatory authority.

The Paroxysmal Nocturnal Hemoglobinuria Pipeline Report Provides Insights into

  • The report provides detailed insights about companies that are developing therapies for the treatment of Paroxysmal Nocturnal Hemoglobinuria with aggregate therapies developed by each company for the same.
  • It accesses the Different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for Paroxysmal Nocturnal Hemoglobinuria Treatment.
  • Paroxysmal Nocturnal Hemoglobinuria Companies are involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.
  • Paroxysmal Nocturnal Hemoglobinuria Drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type.
  • Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement and financing details for future advancement of the Paroxysmal Nocturnal Hemoglobinuria market

Uncover critical updates on therapeutic innovations and their potential impact on patients @ Paroxysmal Nocturnal Hemoglobinuria Unmet Needs

Paroxysmal Nocturnal Hemoglobinuria Companies

Hoffmann-La Roche, Apellis Pharmaceuticals, Regeneron Pharmaceuticals, Biocad, AKARI Therapeutics, Alexion Pharmaceuticals, Novartis Pharmaceuticals, Amgen, BioCryst Pharmaceuticals, MorphoSys, Ra Pharmaceuticals, Alnylam Pharmaceuticals, Arrowhead Pharmaceuticals, Wuhan Createrna Science and Technology, CANbridge, Attune Pharmaceuticals, RallyBio and others.

Paroxysmal Nocturnal Haemoglobinuria pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as

  • Oral
  • Parenteral
  • Intravitreal
  • Subretinal
  • Topical
  • Molecule Type

Paroxysmal Nocturnal Hemoglobinuria Products have been categorized under various Molecule types such as

  • Monoclonal Antibody
  • Peptides
  • Polymer
  • Small molecule
  • Gene therapy
  • Product Type

See the latest progress in drug development and clinical research @ Paroxysmal Nocturnal Hemoglobinuria Market Drivers and Barriers, and Future Perspectives

Scope of the Paroxysmal Nocturnal Hemoglobinuria Pipeline Report

  • Coverage- Global
  • Paroxysmal Nocturnal Hemoglobinuria Companies- Hoffmann-La Roche, Apellis Pharmaceuticals, Regeneron Pharmaceuticals, Biocad, AKARI Therapeutics, Alexion Pharmaceuticals, Novartis Pharmaceuticals, Amgen, BioCryst Pharmaceuticals, MorphoSys, Ra Pharmaceuticals, Alnylam Pharmaceuticals, Arrowhead Pharmaceuticals, Wuhan Createrna Science and Technology, CANbridge, Attune Pharmaceuticals, RallyBio and others.
  • Paroxysmal Nocturnal Hemoglobinuria Pipeline Therapies- HSK39297 tablets, Coversin, MY008211A tablets, Eculizumab Injection, Pegcetacoplan, Crovalimab, Ravulizumab, Iptacopan, LNP023, and others.
  • Paroxysmal Nocturnal Hemoglobinuria Therapeutic Assessment by Product Type: Mono, Combination, Mono/Combination
  • Paroxysmal Nocturnal Hemoglobinuria Therapeutic Assessment by Clinical Stages: Discovery, Pre-clinical, Phase I, Phase II, Phase III

Access the Full Paroxysmal Nocturnal Hemoglobinuria Pipeline Analysis Today! @ Paroxysmal Nocturnal Hemoglobinuria Drugs and Companies

Table of Content

  1. Introduction
  2. Executive Summary
  3. Paroxysmal Nocturnal Hemoglobinuria: Overview
  4. Pipeline Therapeutics
  5. Therapeutic Assessment
  6. Paroxysmal Nocturnal Hemoglobinuria – DelveInsight’s Analytical Perspective
  7. In-depth Commercial Assessment
  8. Paroxysmal Nocturnal Hemoglobinuria Collaboration Deals
  9. Late Stage Products (Phase III)
  10. Crovalimab: Hoffman-La-Roche
  11. Mid Stage Products (Phase II)
  12. BCX9930: BioCryst Pharmaceuticals
  13. Early Stage Products (Phase I)
  14. CAN106: CanBridge
  15. Inactive Products
  16. Paroxysmal Nocturnal Hemoglobinuria Key Companies
  17. Paroxysmal Nocturnal Hemoglobinuria Key Products
  18. Paroxysmal Nocturnal Hemoglobinuria- Unmet Needs
  19. Paroxysmal Nocturnal Hemoglobinuria- Market Drivers and Barriers
  20. Paroxysmal Nocturnal Hemoglobinuria- Future Perspectives and Conclusion
  21. Paroxysmal Nocturnal Hemoglobinuria Analyst Views
  22. Paroxysmal Nocturnal Hemoglobinuria Key Companies
  23. Appendix

About Us

DelveInsight is a leading healthcare-focused market research and consulting firm that provides clients with high-quality market intelligence and analysis to support informed business decisions. With a team of experienced industry experts and a deep understanding of the life sciences and healthcare sectors, we offer customized research solutions and insights to clients across the globe. Connect with us to get high-quality, accurate, and real-time intelligence to stay ahead of the growth curve.

Media Contact
Company Name: DelveInsight Business Research LLP
Contact Person: Yash Bhardwaj
Email: Send Email
Phone: 09650213330
Address:304 S. Jones Blvd #2432
City: Las Vegas
State: NV
Country: United States
Website: https://www.delveinsight.com/report-store/paroxysmal-nocturnal-hemoglobinuria-pipeline-insight

 

Press Release Distributed by ABNewswire.com

To view the original version on ABNewswire visit: Paroxysmal Nocturnal Hemoglobinuria Clinical Trial Pipeline Gains Momentum: 20+ Companies Lead the Charge in Pioneering New Treatments | DelveInsight

Postoperative Acute Pain Market is Expected to Witness Significant Growth by 2036 Driven by Emerging Non-opioid Therapies and Multimodal Pain Management Approaches | DelveInsight

The market dynamics for Postoperative Acute Pain are witnessing steady growth driven by the Increasing Number of Surgical Procedures, Rising Demand for Non-opioid Analgesics, Growing Adoption of Multimodal Pain Management Strategies, and Advancements in Long-acting Local Anesthetic Therapies. Additionally, the launch of emerging therapies such as Cebranopadol (TRN-228), CPL-01, MR-107A-02, LTG-001, ATX101, and others will further fuel the market expansion.

DelveInsight, a leading market research firm, announces the release of its latest report, “DelveInsight’s Postoperative Acute Pain Market Insights, Epidemiology, and Market Forecast–2036.” This comprehensive report provides an in-depth understanding of Postoperative Acute Pain, including historical and forecasted epidemiology, market trends, and treatment scenarios across the United States, EU4 (Germany, Spain, Italy, France), the United Kingdom, and Japan.

Key Takeaways from the Postoperative Acute Pain Market

  • The market size for Postoperative Acute Pain in the leading markets is expected to grow significantly by 2036.

  • As per DelveInsight’s estimates, the total market size of Postoperative Acute Pain was nearly USD 1,200 million in the 7MM in 2025.

  • The United States accounted for the highest Postoperative Acute Pain treatment market size among the 7MM in 2025 compared with the EU4 countries, the United Kingdom, and Japan.

  • Among EU4 and the UK, Germany had the largest market size for Postoperative Acute Pain in 2025.

  • The total number of incident cases of Postoperative Acute Pain in the 7MM were around 89.9 million in 2025.

  • The United States reported approximately 45 million incident cases of Postoperative Acute Pain in 2025, with cases anticipated to increase during the forecast period.

  • In 2025, approximately 14% of the incident cases of Postoperative Acute Pain were reported in Germany.

  • According to a nationwide observational cohort study by Dobbs et al. (2021), a total of 3,102,674 surgical procedures were performed in England and Wales in 2020 compared to a predicted 4,671,338 procedures.

  • In 2025, Japan reported approximately 20%, 15%, and 10% cases of mild, moderate, and severe postoperative acute pain, respectively, out of the 7MM.

  • Leading Postoperative Acute Pain companies such as Vertex Pharmaceuticals, Tris Pharma, Cali Biosciences, Viatris, Allay Therapeutics, Latigo Biotherapeutics, Concentric Analgesics, Xgene Pharmaceutical, and others are developing novel therapies to improve pain management.

  • The promising Postoperative Acute Pain therapies in development include Cebranopadol (TRN-228), CPL-01, MR-107A-02, LTG-001, ATX101, XG005, TLC590, Vocacapsaicin (CA-008), and others.

Keen to know more about the market? Request our sample page athttps://www.delveinsight.com/sample-request/post-operative-acute-pain-market?utm_source=abnewswire&utm_medium=pressrelease&utm_campaign=kspr

Key Factors Driving the Postoperative Acute Pain Market

  • Increasing Number of Surgical Procedures: Rising surgical volumes globally, including inpatient and outpatient procedures, are significantly contributing to the growing burden of postoperative acute pain and demand for effective analgesic therapies.

  • Growing Adoption of Multimodal Analgesia: Current treatment strategies increasingly emphasize multimodal analgesia approaches combining opioids, NSAIDs, local anesthetics, and adjunctive therapies to improve pain relief while minimizing opioid-related risks and adverse events.

  • Rising Demand for Non-opioid Therapies: Concerns regarding opioid dependence, misuse, and associated side effects are accelerating the demand for safer, long-acting, and opioid-sparing treatment alternatives.

  • Advancements in Long-acting and Novel Pain Therapies: The emergence of therapies such as ZYNRELEF, EXPAREL, JOURNAVX, and innovative pipeline agents targeting novel pain pathways is expected to reshape postoperative pain management practices.

Postoperative Acute Pain Competitive Landscape

  • Several Postoperative Acute Pain therapies in development include Cebranopadol (TRN-228) (Tris Pharma), CPL-01 (Cali Biosciences), MR-107A-02 (Viatris), LTG-001 (Latigo Biotherapeutics), ATX101 (Allay Therapeutics), CA-008 (Concentric Analgesics), XG005 (Xgene Pharmaceutical), and others.

  • These therapies target multiple pain pathways and mechanisms, including dual NOP/MOP receptor agonism, selective Nav1.8 inhibition, long-acting local anesthetic delivery, and TRPV1 receptor modulation, aiming to provide improved efficacy with reduced opioid exposure and enhanced postoperative recovery outcomes.

Discover more about therapies set to grab major Postoperative Acute Pain market share @ Postoperative Acute Pain Treatment Landscape

Recent Developments in the Postoperative Acute Pain Market

  • In March 2026, Vertex Pharmaceuticals presented new clinical data on JOURNAVX (suzetrigine) demonstrating effective pain management in postoperative acute pain patients.

  • In April 2026, Tris Pharma announced multiple presentations related to cebranopadol during the 51st Annual Regional Anesthesiology and Acute Pain Medicine Meeting (ASRA).

  • In March 2026, Tris Pharma presented Phase III ALLEVIATE-1 and ALLEVIATE-2 study data evaluating cebranopadol in patients following abdominoplasty and bunionectomy surgery at the American Academy of Pain Medicine (AAPM) 2026 Pain Connect annual meeting.

  • In March 2026, Viatris announced that it anticipates a regulatory decision in the second half of 2026 for MR-107A-02, its fast-acting meloxicam therapy for acute pain.

  • In June 2025, funds were secured to advance the Phase IIb registrational trial of ATX101 in post-surgical pain following total knee replacement.

  • In March 2025, the US FDA granted Fast Track Designation to LTG-001, Latigo Biotherapeutics’ investigational selective Nav1.8 inhibitor for the treatment of acute pain.

What is Postoperative Acute Pain?

Postoperative acute pain is an acute condition experienced by patients following surgical procedures and represents one of the most common complications associated with surgery. Effective pain management is essential to improve recovery, reduce complications, enhance patient outcomes, and shorten hospital stays.

Postoperative pain management involves both pharmacological and non-pharmacological approaches. Current pharmacological options include opioids, NSAIDs, acetaminophen, local anesthetics, corticosteroids, gabapentinoids, alpha-2 agonists, and combination therapies. Non-pharmacological interventions include acupuncture, physical therapy, meditation, cognitive-behavioral approaches, and Transcutaneous Electrical Nerve Stimulation (TENS).

The current treatment paradigm increasingly emphasizes multimodal analgesia strategies that combine therapies with different mechanisms of action to optimize efficacy and reduce opioid-related adverse effects and dependency risks.

Postoperative Acute Pain Epidemiology Segmentation

The Postoperative Acute Pain epidemiology section provides insights into the historical and current patient pool and forecasted trends for the leading markets. The Postoperative Acute Pain market report proffers epidemiological analysis for the study period 2022–2036 in the leading markets, segmented into:

  • Total Incident Cases of Postoperative Acute Pain

  • Severity-specific Incident Cases of Postoperative Acute Pain

  • Total Treated Cases of Postoperative Acute Pain

  • Country-specific Incident Cases of Postoperative Acute Pain

Scope of the Postoperative Acute Pain Market Report

  • Therapeutic Assessment: Postoperative Acute Pain current marketed and emerging therapies

  • Postoperative Acute Pain Market Dynamics: Key Market Forecast Assumptions of Emerging Postoperative Acute Pain Drugs and Market Outlook

  • Key Companies: Vertex Pharmaceuticals, Tris Pharma, Cali Biosciences, Viatris, Allay Therapeutics, Latigo Biotherapeutics, Concentric Analgesics, Xgene Pharmaceutical, and others

  • Key Therapies: JOURNAVX (suzetrigine), ZYNRELEF (HTX-011), EXPAREL, Cebranopadol (TRN-228), CPL-01, MR-107A-02, LTG-001, ATX101, TLC590, and others

  • Competitive Intelligence Analysis: SWOT analysis and Market entry strategies

  • Unmet Needs, KOL’s views, Analyst’s views, Postoperative Acute Pain Market Access and Reimbursement

To know more about Postoperative Acute Pain companies working in the treatment market, visit @ Postoperative Acute Pain Clinical Trials and Therapeutic Assessment

Table of Contents

  1. Postoperative Acute Pain Market Report Introduction

  2. Executive Summary for Postoperative Acute Pain

  3. SWOT Analysis of Postoperative Acute Pain

  4. Postoperative Acute Pain Patient Share (%) Overview at a Glance

  5. Postoperative Acute Pain Market Overview at a Glance

  6. Postoperative Acute Pain Background and Overview

  7. Postoperative Acute Pain Epidemiology and Patient Population

  8. Country-Specific Patient Population of Postoperative Acute Pain

  9. Postoperative Acute Pain Current Treatment and Medical Practices

  10. Postoperative Acute Pain Unmet Needs

  11. Postoperative Acute Pain Emerging Therapies

  12. Postoperative Acute Pain Market Outlook

  13. Country-Wise Postoperative Acute Pain Market Analysis (2022–2036)

  14. Postoperative Acute Pain Market Access and Reimbursement of Therapies

  15. Postoperative Acute Pain Market Drivers

  16. Postoperative Acute Pain Market Barriers

  17. Postoperative Acute Pain Appendix

  18. Postoperative Acute Pain Report Methodology

  19. DelveInsight Capabilities

  20. Disclaimer

  21. About DelveInsight

About DelveInsight

DelveInsight is a leading Business Consultant and Market Research firm focused exclusively on life sciences. It supports pharma companies by providing comprehensive end-to-end solutions to improve their performance. Get hassle-free access to all the healthcare and pharma market research reports through our subscription-based platform PharmDelve.

Media Contact
Company Name: DelveInsight Business Research LLP
Contact Person: Kirti Sharma
Email: Send Email
Phone: +14699457679
Address:304 S. Jones Blvd #2432
City: Las Vegas
State: Nevada
Country: United States
Website: https://www.delveinsight.com/consulting/due-diligence-services

 

Press Release Distributed by ABNewswire.com

To view the original version on ABNewswire visit: Postoperative Acute Pain Market is Expected to Witness Significant Growth by 2036 Driven by Emerging Non-opioid Therapies and Multimodal Pain Management Approaches | DelveInsight

Mild Cognitive Impairment Market to Witness Robust Growth Through 2036 Driven by Rising Aging Population and Emerging Disease-Modifying Therapies | DelveInsight

The Mild Cognitive Impairment (MCI) market is expected to grow significantly during the forecast period owing to the increasing aging population, rising awareness and early diagnosis, expanding use of biomarker-based diagnostics, and the emergence of disease-modifying therapies. Additionally, the launch of promising therapies such as AGB101 (AgeneBio), TRx0237/HMTM (TauRx Therapeutics), OLX-07010 (Oligomerix), and others is expected to further accelerate market growth.

DelveInsight, a leading market research firm, announces the release of its latest report, “DelveInsight’s Mild Cognitive Impairment (MCI) Market Insights, Epidemiology, and Market Forecast–2036.” This comprehensive report provides an in-depth understanding of Mild Cognitive Impairment, including historical and forecasted epidemiology, market trends, and treatment scenarios across the United States, EU4 (Germany, Spain, Italy, France), the United Kingdom, and Japan.

Key Takeaways from the Mild Cognitive Impairment Market

  • The Mild Cognitive Impairment market size in the 7MM is anticipated to increase during the study period 2022–2036.

  • The total market size of Mild Cognitive Impairment in the 7MM was approximately USD 2.4 billion in 2022 and is projected to reach nearly USD 3.7 billion by 2036.

  • The United States accounted for the highest Mild Cognitive Impairment treatment market size among the 7MM in 2025.

  • According to DelveInsight estimates, the US reported approximately 3.5 million cases of MCI due to Alzheimer’s disease in 2025, while Japan accounted for around 2.5 million cases in the same year.

  • A 2015 study using COSMIC protocols estimated the crude prevalence of MCI at 5.9% in both the US and UK, with rates increasing significantly with age.

  • Research from Japan reported crude prevalence rates of 10.9% for amnestic MCI, 12.6% for non-amnestic MCI, and 16.4% for dementia.

  • According to the 2020 US Census, the prevalence of all-cause MCI was 22.7%, reaching 32.0% among African Americans, 25.9% among Hispanics, and 21.1% among Whites.

  • Leading Mild Cognitive Impairment companies, such as AgeneBio, TauRx Therapeutics, Oligomerix, Biogen, Eisai, Eli Lilly, and others, are developing new MCI therapies expected to enter the market in the coming years.

  • The promising Mild Cognitive Impairment therapies in development include AGB101, TRx0237/HMTM, OLX-07010, and others.

Keen to know more about the market? Request our sample page athttps://www.delveinsight.com/sample-request/mild-cognitive-impairment-market?utm_source=abnewswire&utm_medium=pressrelease&utm_campaign=kspr

Key Factors Driving the Mild Cognitive Impairment Market

  • Rising Aging Population and Disease Burden: Advancing age remains the strongest predictor of MCI, with prevalence increasing substantially among individuals aged 60 years and older. The expanding elderly population globally is significantly contributing to the growing patient pool.

  • Increasing Awareness and Early Diagnosis: Greater awareness of cognitive disorders, wider cognitive screening adoption, and increased use of biomarker-based diagnostics are leading to earlier and more accurate identification of MCI cases.

  • Growing Adoption of Disease-modifying Therapies: The approval of LEQEMBI (lecanemab-irmb) and KISUNLA (donanemab-azbt) for early Alzheimer’s disease, including MCI due to Alzheimer’s pathology, marks a major shift from symptomatic management toward disease modification.

  • Expansion of Digital and Neuroprotective Interventions: Emerging therapeutic approaches, including digital therapeutics, tau-targeting therapies, hippocampal modulation strategies, and neuroprotective agents, are expected to broaden treatment opportunities in the coming years.

Mild Cognitive Impairment Competitive Landscape

  • Several Mild Cognitive Impairment therapies in development include AGB101 (AgeneBio), TRx0237/HMTM (TauRx Therapeutics), OLX-07010 (Oligomerix), and others.

  • These therapies target diverse mechanisms such as hippocampal overactivity modulation, tau protein aggregation inhibition, and neuroprotection to slow cognitive decline and disease progression while improving long-term cognitive outcomes in patients with MCI.

Discover more about therapies set to grab major Mild Cognitive Impairment market share @ Mild Cognitive Impairment Treatment Landscape

Recent Developments in the Mild Cognitive Impairment Market

  • In July 2023, Biogen and Eisai’s LEQEMBI (lecanemab) gained US FDA approval for treating MCI or mild dementia stages of Alzheimer’s disease.

  • In September 2023, LEQEMBI received approval in Japan, followed by marketing authorization from the UK MHRA in August 2024.

  • In July 2024, Eli Lilly’s KISUNLA (donanemab-azbt) received US FDA approval for patients in the MCI or mild dementia stage of Alzheimer’s disease.

  • In February 2026, AgeneBio reported new findings supporting AGB101 for patients with MCI due to Alzheimer’s disease, highlighting prevention of amyloid-beta plaque formation.

  • In January 2026, TauRx Therapeutics announced Phase III LUCIDITY trial results demonstrating statistically significant cognitive improvement with TRx0237/HMTM in patients with MCI due to Alzheimer’s disease.

  • In April 2026, TauRx Therapeutics published confirmatory study findings supporting the disease-modifying potential of HMTM in patients with MCI.

  • In July 2025, AgeneBio presented HOPE4MCI clinical trial data at the Alzheimer’s Association International Conference 2025.

  • Oligomerix advanced OLX-07010, a small-molecule inhibitor of tau self-association, into first-in-human Phase Ia clinical trials.

What is Mild Cognitive Impairment (MCI)?

Mild Cognitive Impairment (MCI) represents an intermediate stage between normal age-related forgetfulness and dementia. It is characterized by problems with memory, language, or decision-making that are noticeable to the individual and others around them but do not significantly interfere with daily functioning.

MCI is classified into two major subtypes: Amnestic MCI, primarily affecting memory, and Non-amnestic MCI, which impacts other cognitive abilities such as decision-making, sequencing, and visual perception.

The condition develops due to a combination of modifiable and non-modifiable risk factors. Advancing age remains the strongest predictor, while genetic factors such as the APOE-ε4 allele, vascular disorders, smoking, poor diet, diabetes, hypertension, and physical inactivity also contribute to disease risk.

Diagnosis relies on clinical judgment, cognitive screening, PET imaging, spinal fluid biomarkers, and amyloid-beta testing. Current management approaches include lifestyle modifications, cognitive training, supportive care, and disease-modifying therapies for Alzheimer’s-related MCI.

Mild Cognitive Impairment Epidemiology Segmentation

The Mild Cognitive Impairment epidemiology section provides insights into the historical and current patient pool and forecasted trends for the leading markets. The Mild Cognitive Impairment market report proffers epidemiological analysis for the study period 2022–2036 in the leading markets, segmented into:

  • Total Prevalent Cases of Mild Cognitive Impairment

  • Total Diagnosed Prevalent Cases of Mild Cognitive Impairment

  • Subtype-specific Cases of Mild Cognitive Impairment

  • Age-specific Cases of Mild Cognitive Impairment

  • Associated Disease-specific Cases of Mild Cognitive Impairment

  • Treated Cases of Mild Cognitive Impairment

Scope of the Mild Cognitive Impairment Market Report

  • Therapeutic Assessment: Mild Cognitive Impairment current marketed and emerging therapies

  • Mild Cognitive Impairment Market Dynamics: Key Market Forecast Assumptions of Emerging Mild Cognitive Impairment Drugs and Market Outlook

  • Key Companies: AgeneBio, TauRx Therapeutics, Oligomerix, Biogen, Eisai, Eli Lilly, and others

  • Key Therapies: AGB101, TRx0237/HMTM, OLX-07010, LEQEMBI, KISUNLA, and others

  • Competitive Intelligence Analysis: SWOT analysis and Market entry strategies

  • Unmet Needs, KOL’s views, Analyst’s views, Mild Cognitive Impairment Market Access and Reimbursement

To know more about Mild Cognitive Impairment companies working in the treatment market, visit @ Mild Cognitive Impairment Clinical Trials and Therapeutic Assessment

Table of Contents

  1. Mild Cognitive Impairment Market Report Introduction

  2. Executive Summary for Mild Cognitive Impairment

  3. SWOT Analysis of Mild Cognitive Impairment

  4. Mild Cognitive Impairment Patient Share (%) Overview at a Glance

  5. Mild Cognitive Impairment Market Overview at a Glance

  6. Mild Cognitive Impairment Background and Overview

  7. Mild Cognitive Impairment Epidemiology and Patient Population

  8. Country-Specific Patient Population of Mild Cognitive Impairment

  9. Mild Cognitive Impairment Current Treatment and Medical Practices

  10. Mild Cognitive Impairment Unmet Needs

  11. Mild Cognitive Impairment Emerging Therapies

  12. Mild Cognitive Impairment Market Outlook

  13. Country-Wise Mild Cognitive Impairment Market Analysis (2022–2036)

  14. Mild Cognitive Impairment Market Access and Reimbursement of Therapies

  15. Mild Cognitive Impairment Market Drivers

  16. Mild Cognitive Impairment Market Barriers

  17. Mild Cognitive Impairment Appendix

  18. Mild Cognitive Impairment Report Methodology

  19. DelveInsight Capabilities

  20. Disclaimer

  21. About DelveInsight

About DelveInsight

DelveInsight is a leading Business Consultant and Market Research firm focused exclusively on life sciences. It supports pharma companies by providing comprehensive end-to-end solutions to improve their performance. Get hassle-free access to all the healthcare and pharma market research reports through our subscription-based platform PharmDelve.

Media Contact
Company Name: DelveInsight Business Research LLP
Contact Person: Kirti Sharma
Email: Send Email
Phone: +14699457679
Address:304 S. Jones Blvd #2432
City: Las Vegas
State: Nevada
Country: United States
Website: https://www.delveinsight.com/consulting/due-diligence-services

 

Press Release Distributed by ABNewswire.com

To view the original version on ABNewswire visit: Mild Cognitive Impairment Market to Witness Robust Growth Through 2036 Driven by Rising Aging Population and Emerging Disease-Modifying Therapies | DelveInsight

Intracranial Hemorrhage Market is Expected to Witness Significant Growth by 2036 Due to Advancements in Acute Care Therapies and Emerging Neuroprotective Approaches | DelveInsight

The market dynamics for Intracranial Hemorrhage (ICH) are witnessing steady growth driven by the Increasing Incidence in Aging Populations, Rising Diagnosis and Hospitalization Rates, Growing Use of Anticoagulation Reversal Agents, and Advancements in Acute Neurocritical Care and Minimally Invasive Surgical Techniques. Additionally, the emergence of therapies such as GTx-104 and advances in hemostatic and neuroprotective approaches are expected to further fuel the market expansion.

DelveInsight, a leading market research firm, announces the release of its latest report, “DelveInsight’s Intracranial Hemorrhage (ICH) Market Insights, Epidemiology, and Market Forecast 2036.” This comprehensive report provides an in-depth understanding of Intracranial Hemorrhage, including historical and forecasted epidemiology, market trends, and treatment scenarios across the United States, EU4 (Germany, Spain, Italy, France), the United Kingdom, and Japan.

Key Takeaways from the Intracranial Hemorrhage Market

  • The market size for Intracranial Hemorrhage in the leading markets is expected to grow significantly by 2036.

  • The United States accounted for the highest Intracranial Hemorrhage treatment market size in 7MM in 2025 compared with the EU4 countries, the United Kingdom, and Japan.

  • DelveInsight’s analysis indicates that the total market size of Intracranial Hemorrhage in the 7MM is expected to increase substantially during the forecast period 2022–2036.

  • In the US, the overall incidence of ICH is about 21.1 per 100,000, with a female incidence of 18.4 per 100,000 and a male incidence of 22.8 per 100,000.

  • Data suggests that ICH accounts for approximately 10%–20% of all strokes, with incidence increasing significantly in individuals aged 55 years and older.

  • Epidural hematomas are present in approximately 2% of head injury patients and account for 5% to 15% of fatal head injuries.

  • The incidence of subdural hematoma is estimated to be between 5%–25% of patients with significant head injuries and is associated with an annual incidence of 1 to 5 cases per 100,000 population.

  • Leading Intracranial Hemorrhage companies, such as Grace Therapeutics and others, are developing new ICH therapies that are expected to enter the market in the coming years.

  • The promising Intracranial Hemorrhage therapies in development include GTx-104 (nimodipine) and others.

Keen to know more about the market? Request our sample page athttps://www.delveinsight.com/sample-request/intracranial-hemorrhage-epidemiology-forecast?utm_source=abnewswire&utm_medium=pressrelease&utm_campaign=kspr

Key Factors Driving the Intracranial Hemorrhage Market

  • Increasing Incidence in Aging Populations: The incidence of Intracranial Hemorrhage increases significantly with age, particularly among individuals aged 55 years and older. Aging populations, along with increasing prevalence of hypertension and anticoagulant use, are contributing to the growing patient burden globally.

  • Growing Demand for Acute Neurocritical Care and Minimally Invasive Interventions: Management strategies involving rapid stabilization, minimally invasive surgical approaches, catheter-based interventions, and image-guided hematoma evacuation are gaining traction to improve patient outcomes and reduce neurological complications.

  • Rising Use of Anticoagulation Reversal Agents and Supportive Therapies: Current pharmacologic approaches include anticoagulation reversal agents such as ANDEXXA/ONDEXXYA (andexanet alfa) and PRAXBIND (idarucizumab), alongside blood pressure control and neurocritical supportive care, contributing to expanding treatment utilization.

  • Emerging Neuroprotective and Hemostatic Therapies: The development of therapies targeting vascular integrity, neuroinflammation, hematoma expansion, and neuroprotection is expected to transform the future ICH treatment landscape.

Intracranial Hemorrhage Competitive Landscape

  • Several Intracranial Hemorrhage therapies in development include GTx-104 (Grace Therapeutics) and other investigational therapies focused on neuroprotection, hemostatic intervention, vascular stabilization, and minimally invasive treatment approaches.

  • These therapies aim to improve tolerability, optimize drug delivery, reduce secondary brain injury, limit hematoma expansion, and improve survival and neurological outcomes compared with currently available supportive care approaches.

Discover more about therapies set to grab major Intracranial Hemorrhage market share @ Intracranial Hemorrhage Treatment Landscape

Recent Developments in the Intracranial Hemorrhage Market

  • In February 2026, Balt reported that the US FDA granted premarket approval to its Squid liquid embolic agent for embolization of the middle meningeal artery as an adjunct to standard care in patients with large, symptomatic chronic subdural hematoma.

  • In April 2026, Grace Therapeutics reported that results from its STRIVE-ON Phase III safety trial evaluating GTx-104 were accepted for presentation at the American Academy of Neurology Annual Meeting 2026.

  • In March 2026, Grace Therapeutics announced that abstracts on unmet medical needs and potential benefits of GTx-104 were accepted for presentation at major medical conferences, including the Society of Critical Care Medicine Critical Care Congress 2026.

  • In August 2025, the US FDA accepted the NDA for GTx-104 for formal review, assigning a PDUFA target date in April 2026.

  • In June 2025, Grace Therapeutics submitted a New Drug Application (NDA) to the US FDA for GTx-104 based on positive Phase III STRIVE-ON trial data.

  • In February 2025, Grace Therapeutics announced that its Phase III STRIVE-ON safety trial met its primary endpoint and demonstrated clinical benefit compared with orally administered nimodipine.

What is Intracranial Hemorrhage (ICH)?

Intracranial hemorrhage (ICH) refers to bleeding within the skull and is an important cause of stroke, disability, and mortality. ICH may occur spontaneously or following traumatic injury. Spontaneous ICH is associated with conditions such as hypertension, cerebral amyloid angiopathy, arteriovenous malformations, anticoagulation therapy, ruptured aneurysms, tumors, and venous sinus thrombosis.

Traumatic ICH can occur following head injury, particularly in individuals receiving anticoagulation therapy. Symptoms commonly include severe headache, vomiting, altered consciousness, focal neurological deficits, and neurological deterioration. Neuroimaging techniques such as CT scans and MRI play a critical role in diagnosis and subtype identification.

Intracranial Hemorrhage Epidemiology Segmentation

The Intracranial Hemorrhage epidemiology section provides insights into the historical and current patient pool and forecasted trends for the leading markets. The Intracranial Hemorrhage market report proffers epidemiological analysis for the study period 2022–2036 in the leading markets, segmented into:

  • Total Incident Cases of Intracranial Hemorrhage

  • Gender-specific Cases of Intracranial Hemorrhage

  • Age-specific Cases of Intracranial Hemorrhage

  • Type-specific Cases of Intracranial Hemorrhage

Scope of the Intracranial Hemorrhage Market Report

  • Therapeutic Assessment: Intracranial Hemorrhage current marketed and emerging therapies

  • Intracranial Hemorrhage Market Dynamics: Key Market Forecast Assumptions of Emerging Intracranial Hemorrhage Drugs and Market Outlook

  • Key Companies: Grace Therapeutics and others

  • Key Therapies: GTx-104 (nimodipine), ANDEXXA/ONDEXXYA (andexanet alfa), PRAXBIND (idarucizumab), and others

  • Competitive Intelligence Analysis: SWOT analysis and Market entry strategies

  • Unmet Needs, KOL’s views, Analyst’s views, Intracranial Hemorrhage Market Access and Reimbursement

To know more about Intracranial Hemorrhage companies working in the treatment market, visit @ Intracranial Hemorrhage Clinical Trials and Therapeutic Assessment

Table of Contents

  1. Intracranial Hemorrhage Market Report Introduction

  2. Executive Summary for Intracranial Hemorrhage

  3. SWOT Analysis of Intracranial Hemorrhage

  4. Intracranial Hemorrhage Patient Share (%) Overview at a Glance

  5. Intracranial Hemorrhage Market Overview at a Glance

  6. Intracranial Hemorrhage Background and Overview

  7. Intracranial Hemorrhage Epidemiology and Patient Population

  8. Country-Specific Patient Population of Intracranial Hemorrhage

  9. Intracranial Hemorrhage Current Treatment and Medical Practices

  10. Intracranial Hemorrhage Unmet Needs

  11. Intracranial Hemorrhage Emerging Therapies

  12. Intracranial Hemorrhage Market Outlook

  13. Country-Wise Intracranial Hemorrhage Market Analysis (2022–2036)

  14. Intracranial Hemorrhage Market Access and Reimbursement of Therapies

  15. Intracranial Hemorrhage Market Drivers

  16. Intracranial Hemorrhage Market Barriers

  17. Intracranial Hemorrhage Appendix

  18. Intracranial Hemorrhage Report Methodology

  19. DelveInsight Capabilities

  20. Disclaimer

  21. About DelveInsight

About DelveInsight

DelveInsight is a leading Business Consultant and Market Research firm focused exclusively on life sciences. It supports pharma companies by providing comprehensive end-to-end solutions to improve their performance. Get hassle-free access to all the healthcare and pharma market research reports through our subscription-based platform PharmDelve.

Media Contact
Company Name: DelveInsight Business Research LLP
Contact Person: Kirti Sharma
Email: Send Email
Phone: +14699457679
Address:304 S. Jones Blvd #2432
City: Las Vegas
State: Nevada
Country: United States
Website: https://www.delveinsight.com/consulting/due-diligence-services

 

Press Release Distributed by ABNewswire.com

To view the original version on ABNewswire visit: Intracranial Hemorrhage Market is Expected to Witness Significant Growth by 2036 Due to Advancements in Acute Care Therapies and Emerging Neuroprotective Approaches | DelveInsight

Cushing Syndrome Clinical Trial Pipeline Expands with Robust Contributions from 4+ Global Biopharma Companies | DelveInsight

DelveInsight’s “Cushing Syndrome Pipeline Insight 2026” report provides comprehensive insights about 4+ companies and 4+ pipeline drugs in the Cushing Syndrome pipeline landscape. It covers the Cushing Syndrome Pipeline drug profiles, including clinical and nonclinical stage products. It also covers the Cushing Syndrome Pipeline Therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

Curious about the latest updates in the Cushing Syndrome Pipeline? @ https://www.delveinsight.com/sample-request/cushings-syndrome-pipeline-insight

Key Takeaways from the Cushing Syndrome Pipeline Report

  • On May 12, 2026, Sparrow Pharmaceuticals initiated a clinical trial are to characterize the relationship of clofutriben dose to improved glycemic control, and to identify one or more doses suitable for Phase 3 evaluation, in patients with T2D and elevated cortisol. CAPTAIN-T2D is a two-part, multicenter, randomized, double-blind, parallel group, placebo- controlled trial of the 11-hydroxysteroid dehydrogenase type 1 (HSD-1) inhibitor clofutriben.
  • DelveInsight’s Cushing Syndrome Pipeline report depicts a robust space with 4+ active players working to develop 4+ pipeline therapies for Cushing Syndrome treatment.
  • The leading Cushing Syndrome Companies such as Stero Therapeutics, Sparrow Pharmaceuticals and others.
  • Promising Cushing Syndrome Therapies such as SOM230 LAR 30 mg, Pasireotide LAR, Osilodrostat, SPI-62, Mifepristone, Levoketoconazole, mifepristone, CORT125134 and others.

Want to know which companies are leading innovation in Cushing Syndrome? @ Cushing Syndrome Clinical Trials Assessment

The Cushing Syndrome Pipeline Report provides disease overview, pipeline scenario and therapeutic assessment of the key pipeline therapies in this domain. The Cushing Syndrome Pipeline Report also highlights the unmet needs with respect to the Cushing Syndrome.

Cushing Syndrome Overview

Cushing’s syndrome arises from prolonged exposure to elevated levels of circulating glucocorticoids, with Cushing’s disease, pituitary-dependent hypercortisolism, being the most common cause of endogenous cases. It is characterized by a wide range of symptoms, with common manifestations including decreased libido, obesity or weight gain, plethora (reddish complexion), rounded face, menstrual changes, hirsutism, hypertension, easy bruising (ecchymoses), lethargy, depression, proximal muscle weakness, and skin changes such as striae. Less common symptoms may involve EKG abnormalities or atherosclerosis, dorsal fat pad, edema, abnormal glucose tolerance, osteopenia or fractures, headaches, backaches, recurrent infections, abdominal pain, acne, and female-pattern baldness.

Cushing Syndrome Emerging Drugs

  • ST-002: Stero Therapeutics

ST-002 is specifically designed to address the hyperglycemia and non-alcoholic steatohepatitis (NASH) associated with Cushing’s syndrome, offering a unique combination of glucocorticoid inhibition, anti-inflammatory, and anti-diabetic effects. Unlike other anti-glucocorticoid drugs, ST-002 suppresses glucocorticoid activity without reducing glucocorticoid levels, thereby avoiding adrenal insufficiency. Its safety profile has been established in over 120 patients using prior oral formulations, and as a new chemical entity (NCE), ST-002 demonstrates improved bioavailability and solubility compared to earlier versions. The U.S. FDA has granted it Orphan Disease Designation, and SteroTherapeutics is advancing its development in collaboration with the NIH under a Cooperative Research and Development Agreement (CRADA). Currently, the drug is in Phase II stage of its clinical trial for Cushing Syndrome.

If you’re tracking ongoing Cushing Syndrome Clinical trials, this press release is a must-read @ Cushing Syndrome Treatment Drugs

The Cushing Syndrome Pipeline report provides insights into:-

  • The report provides detailed insights about companies that are developing therapies for the treatment of Cushing Syndrome with aggregate therapies developed by each company for the same.
  • It accesses the Different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for Cushing Syndrome Treatment.
  • Cushing Syndrome Companies are involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.
  • Cushing Syndrome Drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type.
  • Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement and financing details for future advancement of the Cushing Syndrome market.

Cushing Syndrome Companies

Stero Therapeutics, Sparrow Pharmaceuticals and others.

Cushing Syndrome Pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as,

  • Oral
  • Intravenous
  • Subcutaneous
  • Parenteral
  • Topical

Cushing Syndrome Products have been categorized under various Molecule types such as,

  • Recombinant fusion proteins
  • Small molecule
  • Monoclonal antibody
  • Peptide
  • Polymer
  • Gene therapy

From emerging drug candidates to competitive intelligence, the Cushing Syndrome Pipeline Report covers it all @ Cushing Syndrome Market Drivers and Barriers, and Future Perspectives

Scope of the Cushing Syndrome Pipeline Report

  • Coverage- Global
  • Cushing Syndrome Companies- Stero Therapeutics, Sparrow Pharmaceuticals and others.
  • Cushing Syndrome Therapies- SOM230 LAR 30 mg, Pasireotide LAR, Osilodrostat, SPI-62, Mifepristone, Levoketoconazole, mifepristone, CORT125134 and others.
  • Cushing Syndrome Therapeutic Assessment by Product Type: Mono, Combination, Mono/Combination
  • Cushing Syndrome Therapeutic Assessment by Clinical Stages: Discovery, Pre-clinical, Phase I, Phase II, Phase III

Discover what’s next for the Cushing Syndrome Treatment landscape in this detailed analysis @ Cushing Syndrome Emerging Drugs and Major Players

Table of Contents

  1. Introduction
  2. Executive Summary
  3. Cushing Syndrome: Overview
  4. Pipeline Therapeutics
  5. Therapeutic Assessment
  6. Cushing Syndrome– DelveInsight’s Analytical Perspective
  7. Late Stage Products (Phase III)
  8. ST-002: Stero Therapeutics
  9. Drug profiles in the detailed report…..
  10. Mid Stage Products (Phase II)
  11. Drug name: Company name
  12. Drug profiles in the detailed report…..
  13. Early Stage Products (Phase I)
  14. Drug name: Company name
  15. Drug profiles in the detailed report…..
  16. Preclinical and Discovery Stage Products
  17. Drug name: Company name
  18. Drug profiles in the detailed report…..
  19. Inactive Products
  20. Cushing Syndrome Key Companies
  21. Cushing Syndrome Key Products
  22. Cushing Syndrome- Unmet Needs
  23. Cushing Syndrome- Market Drivers and Barriers
  24. Cushing Syndrome- Future Perspectives and Conclusion
  25. Cushing Syndrome Analyst Views
  26. Cushing Syndrome Key Companies
  27. Appendix

About Us

DelveInsight is a leading healthcare-focused market research and consulting firm that provides clients with high-quality market intelligence and analysis to support informed business decisions. With a team of experienced industry experts and a deep understanding of the life sciences and healthcare sectors, we offer customized research solutions and insights to clients across the globe. Connect with us to get high-quality, accurate, and real-time intelligence to stay ahead of the growth curve.

Media Contact
Company Name: DelveInsight Business Research LLP
Contact Person: Yash Bhardwaj
Email: Send Email
Phone: 09650213330
Address:304 S. Jones Blvd #2432
City: Las Vegas
State: NV
Country: United States
Website: https://www.delveinsight.com/report-store/cushings-syndrome-pipeline-insight

 

Press Release Distributed by ABNewswire.com

To view the original version on ABNewswire visit: Cushing Syndrome Clinical Trial Pipeline Expands with Robust Contributions from 4+ Global Biopharma Companies | DelveInsight