DelveInsight’s “Rett Syndrome Market Insights, Epidemiology, and Market Forecast 2032” report delivers an in-depth understanding of the disease, historical and forecasted epidemiology, as well as the Rett Syndrome market size, share, and trends in the seven major markets (7MM) (i.e., the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan).
The Rett Syndrome market report covers emerging drugs, current treatment practices, market share of individual therapies, and current & forecasted market size from 2019 to 2032. It also evaluates the current treatment practice/algorithm, key drivers & barriers impacting the market growth, and unmet medical needs to curate the best of the opportunities and assess the underlying potential of the market.
Rett Syndrome: An Overview
Rett syndrome is a unique neurodevelopmental disorder that is first noticed in infancy and primarily affects girls but can be rarely seen in boys. It is caused by mutations in the X-chromosome on a gene called MECP2. There are more than 200 different mutations found on the MECP2 gene. Most of these mutations are found in eight different “hot spots.” Rett syndrome is mostly misdiagnosed as autism, cerebral palsy, or global developmental delay. It is found in all ethnic and racial groups.
Rett syndrome is part of a spectrum of disorders with the same genetic cause. Other disorders on the spectrum include PPM-X syndrome, MECP2 duplication syndrome, and MECP2-related severe neonatal encephalopathy. These other conditions can affect males.
Rett Syndrome Market Key Facts
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According to the NCARDRS, Rett Syndrome is estimated to affect about one in 12,000 girls born each year and is only rarely seen in males.
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According to a study by Townend et al., Rett syndrome is a neurological disorder that occurs in approximately 1 in 10,000 females.
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As per a study conducted by the Health Programme of the European Union, the estimated prevalence of Rett Syndrome in Europe is 10.0 per 100,000, and the estimated birth prevalence of Rett Syndrome is 5.0 per 100,000.
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Approximately 85-90% of affected people may experience growth failure and muscle wasting that worsens with age.
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Globally, some of the key players involved in developing therapies for Rett Syndrome include Acadia Pharmaceuticals Trofinetide, Anavex Life Sciences (Anavex 2-73), Ultragenyx Pharmaceutical (Dojolvi), and others.
The market outlook section of the report helps to build a detailed comprehension of the historical, current, and forecasted Rett Syndrome market size by analyzing the impact of current and emerging pipeline therapies. It also provides a thorough assessment of the market drivers & barriers, unmet needs, and emerging technologies set to impact the market dynamics.
The report gives complete detail of the Rett Syndrome market trend for each marketed drug and mid & late-stage pipeline therapies by evaluating their impact based on the annual cost of therapy, their Mechanism of Action (MoA), Route of Administration (RoA), molecule types, competition with other therapies, brand value, and their impact on the market.
Rett Syndrome Epidemiology Assessment
The epidemiology section provides insights into the historical, current, and forecasted epidemiology trends in the seven major countries (7MM) from 2019 to 2032. It helps to recognize the causes of current and forecasted epidemiology trends by exploring numerous studies and research. The epidemiology section also provides a detailed analysis of diagnosed and prevalent patient pool, future trends, and and views of key opinion leaders.
The Report Covers the Rett Syndrome Epidemiology Segmented by –
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Total Prevalent Cases of Rett Syndrome
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Gender-specific Prevalent Cases of Rett Syndrome
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Age-specific Prevalent Cases of Rett Syndrome
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Diagnosed and Treatable Cases of Rett Syndrome
Rett Syndrome Drugs Uptake and Pipeline Development Activities
The drugs uptake section focuses on the rate of uptake of the potential drugs recently launched in the Rett Syndrome market or expected to get launched during the study period. The analysis covers the Rett Syndrome market uptake by drugs, patient uptake by therapies, and sales of each drug.
Moreover, the therapeutics assessment section helps understand the drugs with the most rapid uptake and the reasons behind the maximal use of the drugs. Additionally, it compares the drugs based on market share.
The report also covers the Rett Syndrome Pipeline Development Activities. It provides valuable insights about different therapeutic candidates in various stages and the key companies involved in developing targeted therapeutics. It also analyses recent developments such as collaborations, acquisitions, mergers, licensing patent details, and other information for emerging therapies.
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Rett Syndrome Therapeutics Analysis
The dynamics of the Rett Syndrome market are anticipated to change in the coming years owing to the improvement in the research and development activities in the therapeutics market.
Some of the key companies in the Rett Syndrome market include:
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Neuren Pharmaceuticals
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GW Research
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Anavex Life Sciences
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Acadia Pharmaceuticals
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Ultragenyx Pharmaceutical
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AMO Pharma
And many others.
Rett Syndrome Therapies covered in the report includes:
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NNZ-2566
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GWP42003-P
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Anavex2-73
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Trofinetide
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Dojolvi
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AMO-4
And many others.
Further Emerging Drugs & Key Companies are Covered in the Report. Download the Sample PDF to Learn More @
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Table of Content (TOC)
1. Key Insights
2. Executive Summary
3. Rett Syndrome Competitive Intelligence Analysis
4. Rett Syndrome Market Overview at a Glance
5. Rett Syndrome Disease Background and Overview
6. Rett Syndrome Patient Journey
7. Rett Syndrome Epidemiology and Patient Population (In the US, EU5, and Japan)
8. Rett Syndrome Treatment Algorithm, Current Treatment, and Medical Practices
9. Rett Syndrome Unmet Needs
10. Key Endpoints of Rett Syndrome Treatment
11. Rett Syndrome Marketed Products
12. Rett Syndrome Emerging Drugs and Latest Therapeutic Advances
13. Rett Syndrome Seven Major Market Analysis
14. Attribute Analysis
15. Rett Syndrome Market Outlook (In US, EU5, and Japan)
16. Rett Syndrome Access and Reimbursement Overview
17. KOL Views on the Rett Syndrome Market
18. Rett Syndrome Market Drivers
19. Rett Syndrome Market Barriers
20. Appendix
21. DelveInsight Capabilities
22. Disclaimer
*The Table of Contents (TOC) is not exhaustive; the final content may vary. Refer to the sample report for the complete table of contents.
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Rett Syndrome Pipeline Insights
DelveInsight’s “Rett Syndrome – Pipeline Insight, 2022” report provides comprehensive insights about 20+ companies and 20+ pipeline drugs in the Rett Syndrome therapeutics landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
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